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ilvI from Neisseria meningitidis 053442

Victor ID 2891
Gene Name ilvI from Neisseria meningitidis 053442
Sequence Strain (Species/Organism) Neisseria meningitidis 053442
NCBI Gene ID 5795606
NCBI Protein GI 161870432
Locus Tag NMCC_1480
Protein Accession YP_001599604.1
Other Database IDs UniProtKB-ID: A9M180_NEIM0
UniRef100: UniRef100_A9M180
UniRef90: UniRef90_B4RJ12
UniRef50: UniRef50_Q89AP7
UniParc: UPI000161075E
EMBL: CP000381
EMBL-CDS: ABX73645.1
RefSeq_NT: NC_010120.1
EnsemblGenome: EBNEIG00000011697.
EnsemblGenome_TRS: EBNEIT00000011697
EnsemblGenome_PRO: EBNEIP00000011239
GenomeReviews: CP000381_GR
KEGG: nmn:NMCC_1480
HOGENOM: HBG323037
OMA: ANLAMQN
ProtClustDB: CLSK878135
BioCyc: NMEN374833:NMCC_1480-MONOMER
Taxonomy ID 374833
Gene Starting Position 1507885
Gene Ending Position 1509612
Gene Strand (Orientation) -
Protein Name acetolactate synthase isozyme III large subunit
DNA Sequence 
>gi|161869018:1507885-1509612 Neisseria meningitidis 053442, complete genome
CTTACGCCTTTTCGTCCGCACGCATATGCGGCGGAAGTACCATTTCGTCCAAACCTTTGCCGTTGCCGAC
CATGGGCATCACATTCTGTTTCTGGTCGGTCAGGAAGTCGATAAACACCAGCCTGTCTTTTTGGTTCAAT
GCTTCCAACAACGCACCTTCCACATCAGACTTCTTGTCCACGCGGATGCCGATATGACCGTATGCCTCGG
CAAGTTTGACGAAATCGGGCAAAGAATCGAAATAAGTTTCCGACTCTCGGCCGCCGTAATATATTTCCTG
CCACTGGCGTACCATACCGAGATAACCGTTGTTCAGCGTAATGACGTTAACCGGAATCCGATATTGGAAA
CAGGTGGACAACTCTTGGATGTTCATCTGAATCGAGCCGTCGCCGGTAATACAGAATACGTCTTGATCCG
GGGCGGCAAGTTTTGCACCAATCGCATAAGGCAGACCCACGCCCATCGTACCCAAACCGCCGGAATTGAG
CCATTGGCGCGGACGTTCGAAGGGATAATATTGAGCCGCAAACATTTGATGCTGCCCTACATCCGATGTG
ATGATTGCCGAATTGCCGGTAATCTCGGCAAGCTTCTGAATCACATATTGGGGCTTGATAATTTCGCTGC
CGTTGTCAAACCACAAGCAATCTCGGGAACGCCATTCCTCTATGGTTTTCCACCATTTGCCCAAAGTATC
TTCAGACGGCACGGACTCTTGTTTTTGCCACAGCGCAACCATCTCGGACAAAACGTTTTTCACGTCGCCG
ACAATCGGAATGTCCGCCTTCACGCGTTTGGCGATGCTGGAAGGATCGACATCGATATGGATAACCTTCT
TCGCCTTCTCGAAAAATTTGGACGGTACGGAAACCACACGGTCGTCAAAACGCGCACCTACGGCAAGAAC
GACATCCGCATTCTGCATGGCAAGGTTTGCCTCGTAAGTACCGTGCATACCGAGCATACCGAGGAATTGG
CGGTCGCCGGAAGGATAAGCGCCCAAGCCCATCAGCGTACCCGTGCACGGAGCACCCGTCATTCGGACAA
ATCGGGTCAGCTCTTCAGAAGCATTACCCAACACCACGCCGCCGCCAAAATAGACGACCGGACGTTTGGC
AGATGCCAACATCTGCACGGCCTTTTTAATCTGACCGATATGCCCTTGAACAACCGGTTGATACGAACGG
ATAAAAATGTCTTCCTGAGGATAGCTGAATTTCGCCATCGCCTGCGTAACATCTTTCGGGACATCAACCA
CCACGGGCCCCGGTCGGCCGCTTGCGGCAATTTGGAACGCCTTTTTAATGGTTTCCGCCAACTCATTGAT
GTCCGTAACCAGGAAATTGTGTTTGACGCACGGACGGGTAATACCCACCGTATCAACTTCTTGGAACGCA
TCCGTACCAATCAGGGAATTGCCTACCTGCCCGCTGATGACCACCATCGGAATCGAATCCGTATAGGCAG
TAGCAATACCGGTCAGTGCATTGGTAACGCCCGGGCCGGATGTAACCAATGCCACGCCCACCTTACCGCT
GACGCGCGCATACGCATCTGCCGCGTGTACTGCCGCCTGCTCGTGACGGGTCAGAATGTGCTTGAATTTA
TTGAGTTGGAAAAGGGCATCGTAGATTTCGATAACCGCACCGCCGGGATAACCGAAAACGTACTCGACAC
CTTCGGCTTTGAGACTCTGCACTATGATTTGCGCGCCTGATAACTGCA
Protein Sequence 
>gi|161870432|ref|YP_001599604.1| acetolactate synthase isozyme III large subunit [Neisseria meningitidis 053442] MQLSGAQIIVQSLKAEGVEYVFGYPGGAVIEIYDALFQLNKFKHILTRHEQAAVHAADAYARVSGKVGVALVTSGPGVTNALTGIATAYTDSIPMVVISGQVGNSLIGTDAFQEVDTVGITRPCVKHNFLVTDINELAETIKKAFQIAASGRPGPVVVDVPKDVTQAMAKFSYPQEDIFIRSYQPVVQGHIGQIKKAVQMLASAKRPVVYFGGGVVLGNASEELTRFVRMTGAPCTGTLMGLGAYPSGDRQFLGMLGMHGTYEANLAMQNADVVLAVGARFDDRVVSVPSKFFEKAKKVIHIDVDPSSIAKRVKADIPIVGDVKNVLSEMVALWQKQESVPSEDTLGKWWKTIEEWRSRDCLWFDNGSEIIKPQYVIQKLAEITGNSAIITSDVGQHQMFAAQYYPFERPRQWLNSGGLGTMGVGLPYAIGAKLAAPDQDVFCITGDGSIQMNIQELSTCFQYRIPVNVITLNNGYLGMVRQWQEIYYGGRESETYFDSLPDFVKLAEAYGHIGIRVDKKSDVEGALLEALNQKDRLVFIDFLTDQKQNVMPMVGNGKGLDEMVLPPHMRADEKA
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: ilvI mutant is attenuated in rats (Sun et al., 2000).
COG COG0028EH, under E: Amino acid transport and metabolism; H: Coenzyme transport and metabolism
References
Sun et al., 2000: Sun YH, Bakshi S, Chalmers R, Tang CM. Functional genomics of Neisseria meningitidis pathogenesis. Nature medicine. 2000; 6(11); 1269-1273. [PubMed: 11062540].