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mkl

Victor ID 289
Gene Name mkl
Sequence Strain (Species/Organism) Mycobacterium tuberculosis H37Rv
NCBI Gene ID 888081
NCBI Protein GI 15607795
Locus Tag Rv0655
Protein Accession NP_215169.1
Other Database IDs UniProtKB-ID: MKL_MYCTU
UniRef100: UniRef100_P63358
UniRef90: UniRef90_P63358
UniRef50: UniRef50_P63358
UniParc: UPI000012F19C
EMBL: BX842574
EMBL: AE000516
EMBL-CDS: CAB09379.1
EMBL-CDS: AAK44909.1
RefSeq_NT: NC_000962.2
RefSeq_NT: NC_002755.2
TCDB: 3.A.1.27.5
EnsemblGenome: EBMYCG00000002079
EnsemblGenome_TRS: EBMYCT00000002081
EnsemblGenome_PRO: EBMYCP00000002081
EnsemblGenome: EBMYCG00000069948
EnsemblGenome_TRS: EBMYCT00000069953
EnsemblGenome_PRO: EBMYCP00000068012
GenomeReviews: AE000516_
Taxonomy ID 83332
Gene Starting Position 751516
Gene Ending Position 752595
Gene Strand (Orientation) +
Protein Name POSSIBLE RIBONUCLEOTIDE-TRANSPORT ATP-BINDING PROTEIN ABC TRANSPORTER MKL
DNA Sequence 
>gi|57116681:751516-752595 Mycobacterium tuberculosis H37Rv, complete genome
GGTGCGATACAGTGACTCATACCACACAACGGGCCGGTGGCAGCCACGAGCGTCGACAGAAGGGTTTCCC
ATGGGCGTCAGCATCGAGGTCAACGGACTAACGAAGTCCTTCGGGTCCTCGAGGATCTGGGAAGATGTCA
CGCTAACGATCCCCGCCGGGGAGGTCAGCGTGCTGCTGGGCCCATCGGGTACCGGCAAATCGGTGTTTCT
GAAATCTCTGATCGGCCTCCTGCGGCCGGAGCGCGGCTCGATCATCATCGACGGCACCGACATCATCGAA
TGCTCGGCCAAGGAGCTTTACGAGATCCGCACATTGTTCGGCGTGCTGTTTCAGGACGGTGCCCTGTTCG
GGTCGATGAACCTCTACGACAACACCGCGTTCCCCCTGCGTGAGCACACCAAGAAAAAGGAAAGCGAGAT
CCGTGACATCGTCATGGAGAAGCTGGCCCTAGTCGGCCTGGGTGGGGACGAGAAGAAGTTCCCCGGCGAG
ATCTCCGGCGGGATGCGTAAGCGTGCCGGCCTAGCGCGTGCCCTGGTCCTTGACCCGCAGATCATTCTCT
GCGACGAGCCCGACTCGGGTCTGGACCCGGTTCGTACCGCCTACCTGAGCCAGCTGATCATGGACATCAA
CGCCCAGATCGACGCCACCATCCTGATCGTGACGCACAACATCAACATCGCCCGCACCGTGCCGGACAAC
ATGGGCATGTTGTTCCGCAAGCATTTGGTGATGTTCGGGCCGCGGGAGGTGCTACTCACCAGCGACGAGC
CGGTGGTGCGGCAGTTCCTCAACGGCCGGCGCATCGGCCCGATCGGCATGTCCGAGGAGAAGGACGAGGC
CACCATGGCCGAAGAGCAGGCCCTGCTCGATGCCGGCCACCACGCGGGCGGTGTCGAGGAAATCGAGGGC
GTGCCGCCGCAGATCAGCGCGACACCGGGCATGCCGGAGCGCAAAGCGGTCGCCCGGCGTCAGGCTCGGG
TTCGCGAGATGTTGCACACGCTGCCCAAAAAGGCCCAGGCGGCGATCCTCGACGATCTCGAGGGCACGCA
CAAGTACGCGGTGCACGAAATCGGCCAGTA
Protein Sequence 
>gi|15607795|ref|NP_215169.1| ribonucleotide ABC transporter ATP-binding protein [Mycobacterium tuberculosis H37Rv] MRYSDSYHTTGRWQPRASTEGFPMGVSIEVNGLTKSFGSSRIWEDVTLTIPAGEVSVLLGPSGTGKSVFLKSLIGLLRPERGSIIIDGTDIIECSAKELYEIRTLFGVLFQDGALFGSMNLYDNTAFPLREHTKKKESEIRDIVMEKLALVGLGGDEKKFPGEISGGMRKRAGLARALVLDPQIILCDEPDSGLDPVRTAYLSQLIMDINAQIDATILIVTHNINIARTVPDNMGMLFRKHLVMFGPREVLLTSDEPVVRQFLNGRRIGPIGMSEEKDEATMAEEQALLDAGHHAGGVEEIEGVPPQISATPGMPERKAVARRQARVREMLHTLPKKAQAAILDDLEGTHKYAVHEIGQ
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: attenuated in mice (Sassetti and Rubin, 2003).
COG COG1127Q, under Q: Secondary metabolites biosynthesis, transport and catabolism
References
Sassetti and Rubin, 2003: Sassetti CM, Rubin EJ. Genetic requirements for mycobacterial survival during infection. Proceedings of the National Academy of Sciences of the United States of America. 2003; 100(22); 12989-12994. [PubMed: 14569030].