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fhs from Neisseria meningitidis 053442

Victor ID 2882
Gene Name fhs from Neisseria meningitidis 053442
Sequence Strain (Species/Organism) Neisseria meningitidis 053442
NCBI Gene ID 5795151
NCBI Protein GI 161869376
Locus Tag NMCC_0383
Protein Accession YP_001598543.1
Other Database IDs UniProtKB-ID: FTHS_NEIM0
UniRef100: UniRef100_A9M1J1
UniRef90: UniRef90_Q5FAG1
UniRef50: UniRef50_Q2RM91
UniParc: UPI0001610337
EMBL: CP000381
EMBL-CDS: ABX72589.1
RefSeq_NT: NC_010120.1
EnsemblGenome: EBNEIG00000012464
EnsemblGenome_TRS: EBNEIT00000012464
EnsemblGenome_PRO: EBNEIP00000012006
GenomeReviews: CP000381_GR
KEGG: nmn:NMCC_0383
HOGENOM: HBG677721
OMA: KMPGLPK
ProtClustDB: PRK13505
BioCyc: NMEN374833:NMCC_0383-MONOMER
Taxonomy ID 374833
Gene Starting Position 385584
Gene Ending Position 387260
Gene Strand (Orientation) +
Protein Name formate--tetrahydrofolate ligase
DNA Sequence 
>gi|161869018:385584-387260 Neisseria meningitidis 053442, complete genome
CATGAGCTTCAAAACCGATGCCGAAATCGCCCAGTCTTCCACCATGCGCCCGATTGGCGAAATTGCCGCC
AAGCTGGGCCTGAACGCCGACAACATTGAGCCTTACGGTCACTACAAAGCCAAAATCAATCCTGCCGAAG
CATTCAAGCTGCCGCAAAAACAAGGCCGTCTGATTTTGGTTACTGCCATTAATCCGACTCCTGCGGGTGA
GGGTAAAACCACAGTAACCATCGGTTTGGCGGATGCGTTGCGCCATATCGGCAAAGACTCGGTTATCGCC
CTACGCGAACCTTCTTTGGGGCCGGTGTTCGGTGTTAAAGGCGGTGCGGCAGGCGGCGGCTATGCCCAAG
TTTTGCCGATGGAAGACATCAACCTGCACTTCACCGGAGATTTTCACGCCATCGGTGCGGCAAATAATCT
GCTTGCCGCGATGCTCGACAACCATATCTATCAGGGCAACGAGTTGGACATCGACCCCAAACGCGTGCTG
TGGCGGCGCGTGGTCGATATGAACGACCGTCAGTTGCGCAACATCATCGACGGCATGGGCAAACCTGTTG
ACGGCGTGATGCGTCCCGACGGTTTCGATATTACCGTTGCCTCCGAAGTGATGGCGGTATTCTGTCTTGC
CAAAGACATCAGCGATTTGAAAGAGCGTTTGGGCAACATCCTTGTCGCCTACGCCAAAGACGGCAGCCCC
GTTTACGCCAAAGATTTGAAAGCGAATGGCGCGATGGCGGCATTGCTTAAAGATGCGATTAAGCCCAACT
TGGTGCAAACCATCGAAGGCACGCCCGCCTTCGTACACGGCGGCCCGTTCGCCAACATCGCCCACGGCTG
CAACTCCGTAACCGCAACCCGTCTGGCGAAACACCTTGCCGATTACGCCGTAACCGAAGCAGGCTTCGGC
GCGGACTTGGGCGCGGAAAAATTCTGCGACATCAAATGCCGCCTTGCCGGTTTGAAACCTGATGCGGCTG
TTGTCGTGGCGACTGTCCGCGCGTTGAAATATAACGGCGGCGTGGAACGCGCCAACCTCGGCGAAGAAAA
TTTAGACGCTTTGGAAAAAGGTTTGCCCAACCTGCTGAAACACATTTCCAACCTGAAAAACGTATTCGGA
CTGCCCGTCGTCGTTGCGCTCAACCGCTTCGTGTCCGACTCCGATGCCGAGTTGGCGATGATTGAAAAAG
CCTGTGCCGAACACGGCGTTGAAGTTTCCCTGACCGAAGTGTGGGGCAAAGGTGGTGCGGGCGGCGCGGA
TTTGGCGCGCAAAGTCGTCAACGCCATTGAAAGTCAAACCAATAACTTCGGTTTCGCCTACGATGTCGAG
TTGGGCATCAAAGACAAAATCCGTGCGATTGCCCAAAAAGTGTACGGCGCGGAAGATGTTGATTTCAGCG
CGGAAGCGTCTGCCGAAATCGCTTCACTGGAAAAACTGGGCTTGGACAAAATGCCGATCTGCATGGCGAA
AACCCAATACTCTTTGAGTGACAACGCCAAACTGTTGGGCTGCCCCGAAGGCTTCCGCATCGCCGTGCGC
GGCATCACCGTTTCCGCCGGCGCGGGCTTCATCGTCGCGCTGTGCGGCAATATGATGAAGATGCCGGGTC
TGCCGAAAGTTCCGGCCGCCGAGAAAATCGATGTGGACGAACACGGCGTGATTCACGGCTTGTTCTG
Protein Sequence 
>gi|161869376|ref|YP_001598543.1| formate--tetrahydrofolate ligase [Neisseria meningitidis 053442] MSFKTDAEIAQSSTMRPIGEIAAKLGLNADNIEPYGHYKAKINPAEAFKLPQKQGRLILVTAINPTPAGEGKTTVTIGLADALRHIGKDSVIALREPSLGPVFGVKGGAAGGGYAQVLPMEDINLHFTGDFHAIGAANNLLAAMLDNHIYQGNELDIDPKRVLWRRVVDMNDRQLRNIIDGMGKPVDGVMRPDGFDITVASEVMAVFCLAKDISDLKERLGNILVAYAKDGSPVYAKDLKANGAMAALLKDAIKPNLVQTIEGTPAFVHGGPFANIAHGCNSVTATRLAKHLADYAVTEAGFGADLGAEKFCDIKCRLAGLKPDAAVVVATVRALKYNGGVERANLGEENLDALEKGLPNLLKHISNLKNVFGLPVVVALNRFVSDSDAELAMIEKACAEHGVEVSLTEVWGKGGAGGADLARKVVNAIESQTNNFGFAYDVELGIKDKIRAIAQKVYGAEDVDFSAEASAEIASLEKLGLDKMPICMAKTQYSLSDNAKLLGCPEGFRIAVRGITVSAGAGFIVALCGNMMKMPGLPKVPAAEKIDVDEHGVIHGLF
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: fhs mutant is attenuated in rats (Sun et al., 2000).
COG COG2759F, under F: Nucleotide transport and metabolism
References
Sun et al., 2000: Sun YH, Bakshi S, Chalmers R, Tang CM. Functional genomics of Neisseria meningitidis pathogenesis. Nature medicine. 2000; 6(11); 1269-1273. [PubMed: 11062540].