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Rv3378c

Victor ID 288
Gene Name Rv3378c
Sequence Strain (Species/Organism) Mycobacterium tuberculosis H37Rv
NCBI Gene ID 888075
NCBI Protein GI 15610514
Locus Tag Rv3378c
Protein Accession NP_217895.1
Other Database IDs UniProtKB-ID: O50407_MYCTU
UniRef100: UniRef100_A5U852
UniRef90: UniRef90_A5U852
UniRef50: UniRef50_A1KP70
UniParc: UPI00000D1176
EMBL: AE000516
EMBL: BX842582
EMBL-CDS: AAK47824.1
EMBL-CDS: CAA15763.1
RefSeq_NT: NC_000962.2
RefSeq_NT: NC_002755.2
EnsemblGenome: EBMYCG00000003593.
EnsemblGenome_TRS: EBMYCT00000003595
EnsemblGenome_PRO: EBMYCP00000003595
EnsemblGenome: EBMYCG00000070809.
EnsemblGenome_TRS: EBMYCT00000070814
EnsemblGenome_PRO: EBMYCP00000068873
GenomeReviews: AE000516_GR
GenomeRev
Taxonomy ID 83332
Gene Starting Position 3792357
Gene Ending Position 3793247
Gene Strand (Orientation) -
Protein Name hypothetical protein
DNA Sequence 
>gi|57116681:3792357-3793247 Mycobacterium tuberculosis H37Rv, complete genome
ATCAGCCCTCCGCGAACCAGATTCCATCATGAACACAACCCACACCGAAAACTCTGTCAGGCTGGGCTCG
ATATCTGTTGCGCAGTACATTGAGCTGATCGGCCGACATCGCTGAATAGTCAGGTTTGGGCCGGAAATGA
CGGAGATAGATATGATCGTACAAGATCCTCCGGAGCGTTGTTTCGGTCATATAGTATGAGGGAGCAACGG
TGAAGTATAGACTCGTTTTTCCTGAGCTGAGCAGCGGAAAATCGAAAGTGCTGAAACGCCCAAATCCGAT
GAACATGTCAGCCTTGTCAACATACTCGCCGTAATAACCTTCGATAATCTCTCTCCGCGTGGGAGGTTTA
CCATGCGTTTCGTTCCACGAGATAGAAAACTGCGCAACAGACTCAGCCGCATCGTTGCCAAAAACACCGA
AGCATAGTCTGTGTTCAGTGTTGGATGACGTAGAGATTGTTAGGTCATCGAATGACTTGACAACGGCTGC
CCCTTGCGCGGTCGAAGGCAATCTTTTCTTATAATCACCATAAAAAAGAACGTGGACCTCGTGTTCTTTA
TAGAACGACAGAATTTCCTCGTCGTTGGCAAGCAAGGCCATCCCTTCGAGCGCCTGTACGATATATCGAT
CACCACGATCCAGAAGATCGTCGCTAAAGATTGGCGAGATTACTGTTTCGATGCCGTGCTCGAAGAGCAT
CTTCAGAATACGAATTGATTGACGCAAGGCGGCCTGCTGATAATCGTCGTACTGCGGATTACATTCGAGG
TGAAACCAGCGGCGTGTGCCATCGAAGGGAAAGACGGATACCTTCGGTCCACGGCAACGTACAATCTCTG
CTACGGATACTAGAGGAAGATCCAAGAATTCTTTTTCGCTAACCAAGTTCA
Protein Sequence 
>gi|15610514|ref|NP_217895.1| diterpene synthase [Mycobacterium tuberculosis H37Rv] MNLVSEKEFLDLPLVSVAEIVRCRGPKVSVFPFDGTRRWFHLECNPQYDDYQQAALRQSIRILKMLFEHGIETVISPIFSDDLLDRGDRYIVQALEGMALLANDEEILSFYKEHEVHVLFYGDYKKRLPSTAQGAAVVKSFDDLTISTSSNTEHRLCFGVFGNDAAESVAQFSISWNETHGKPPTRREIIEGYYGEYVDKADMFIGFGRFSTFDFPLLSSGKTSLYFTVAPSYYMTETTLRRILYDHIYLRHFRPKPDYSAMSADQLNVLRNRYRAQPDRVFGVGCVHDGIWFAEG
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: Rv3378c mutant is attenuated in survival within macrophages (Pethe et al., 2004).
References
Pethe et al., 2004: Pethe K, Swenson DL, Alonso S, Anderson J, Wang C, Russell DG. Isolation of Mycobacterium tuberculosis mutants defective in the arrest of phagosome maturation. Proceedings of the National Academy of Sciences of the United States of America. 2004; 101(37); 13642-13647. [PubMed: 15340136].