Search: for Help
About
Introduction
Statistics
Your PHIDIAS
Register or Login
Philert
Submission
Curated Data
Victors
BBP (Brucella)
Phinfo
Phinet
HazARD
Data Analysis
Phigen
Pacodom
BLAST
Help & Documents
Documents
FAQs
Links
Acknowledgements
Disclaimer
Contact Us
UMMS Logo

Rv3377c

Victor ID 287
Gene Name Rv3377c
Sequence Strain (Species/Organism) Mycobacterium tuberculosis H37Rv
NCBI Gene ID 888073
NCBI Protein GI 15610513
Locus Tag Rv3377c
Protein Accession NP_217894.1
Other Database IDs UniProtKB-ID: O50406_MYCTU
UniRef100: UniRef100_C6DLB8
UniRef90: UniRef90_C6DLB8
UniRef50: UniRef50_C6DLB8
UniParc: UPI00000D4F72
EMBL: BX842582
EMBL-CDS: CAA15762.1
RefSeq_NT: NC_000962.2
EnsemblGenome: EBMYCG00000000767.
EnsemblGenome_TRS: EBMYCT00000000767
EnsemblGenome_PRO: EBMYCP00000000767
GenomeReviews: AL123456_GR
KEGG: mtu:Rv3377c
TubercuList: Rv3377c
HOGENOM: HBG131188
OMA: FEETAYA
ProtClustDB: CLSK864468
BioCyc: MetaCyc:MONOMER-13989
Taxonomy ID 83332
Gene Starting Position 3790847
Gene Ending Position 3792352
Gene Strand (Orientation) -
Protein Name POSSIBLE CYCLASE
DNA Sequence 
>gi|57116681:3790847-3792352 Mycobacterium tuberculosis H37Rv, complete genome
CTCATTGGTTACTCTCATCGACCAGCCGCAGTGCACTTAGGATGGCAGCCTTAACTACCGTCGCCGAGCA
GTAAAGTGTCTTGGCAATCCACAACGGCGCGTATGGCGGTTCGCAGTGTTGCGATAGCCACCCACCCGCG
CGACTGATCTGCGCCGACAAGGATGTGCCGCTGTGCCTCTGCCAATGCGCCAGAGCTTGAATGCAATATG
CTGTCTCTTCCGCAGTCGCTTGGCCGTCGAAAAATCCCCACGAGCCATCGGGCCTCTGCGTATTAAGAAT
CCACCCAATCGCATCTGAGCATAGGGCATCATCATAGTTACTGGCAGCACATATCAGATGCGCAGTCGTA
TAATATGCCGATCGGTGCCACTTATCCCGCCAGCAGAACCGTCCAGGCTCCTTGCTTGATCGGATGAATT
CCAGAACCTTTCGTACTCGTGGATGACATTTGTCGTAGCCCGCCTGCTTCAACGCACCGAGCACGTGGAC
GTTCGTCGATATCGAGGGGCCGACTTCGTGAAAGTAGGTACGGAACCAATCGGCGTCTTCGAATTGTAAT
ACGGCTCCGATATCCGGCGACCGTCCAAACTTCGACAAAACATCGTAGGCCACACTTGTGGTGTCACAAT
CTTCCAAGGTGGAATTTCCTGTCCACCCCACACCTCGACCACGGACCCAATGTTGTTCGACATGGTCAAG
ATAGGGTAGGTACGTACGAACGATCTCAGGATCGGACAAATCAATATCCGTACGCGAGAGATTCCATAGA
GACCAAACAATTTCAAAAATCTCGGCTTGATAGAAGGCCGGCGCACCGCCATCGCCGGCTTGAATTATCG
ATGAGATGTACGCCAAGGCCCGCTTGTCTCCTGGTTTAACATGTAACGCGAAGTAGGCTGACGCTGATGG
CGAATACTTGACCGATCCATTTGTCTCCTGCAAGTTATCGACATCCAACATACCGACACCGTCTTGGCCG
GCCAGTTCTACGGAGAAAGCTGCGGTGATATGTTTATTGATTTTGCTTCCGCCGAGTTTTCTCAACTTCT
GCTCACGCACTCCGACAAGCTCGCCGAGGATGGATTCCTCGTGGCAAATGGCAAGGCCAAGTCGCGCCGC
CTCAGCCATCAGCGTAGGTGCGATTAACTCAAACCCGACGGTTGCGTCTTTTATATCAAGTTGAGGGCCT
TCGAAAGCACCCGAGGTAAGGTTCTTCAGGGCTAGCAAGCCTTTTTCAACTTGCGCTGCGCGCCTCCGAC
GATGCTTATTCGACGTGAGGCTGATCATGGCCGCCAAAGTGGAGAGCAGTCGATCTTCGTAGCAGAAAGG
GAACTCGGCTCCCCATGAGCCGTCAGGAAGCTGGCGCTCGCAAAGCCAGTTGAGGGCGAGGTCGCTTAGC
TCATCATCGAGCTGGCCCAGCTTCGCGACCCACGCGGTGTCATAGGCTGTGCTCGAGATGCCGTTGCCTA
GTGCCGCTTTCGCTAGCAGAGTCCTGAAAGTCTCCA
Protein Sequence 
>gi|15610513|ref|NP_217894.1| type B diterpene cyclase [Mycobacterium tuberculosis H37Rv] METFRTLLAKAALGNGISSTAYDTAWVAKLGQLDDELSDLALNWLCERQLPDGSWGAEFPFCYEDRLLSTLAAMISLTSNKHRRRRAAQVEKGLLALKNLTSGAFEGPQLDIKDATVGFELIAPTLMAEAARLGLAICHEESILGELVGVREQKLRKLGGSKINKHITAAFSVELAGQDGVGMLDVDNLQETNGSVKYSPSASAYFALHVKPGDKRALAYISSIIQAGDGGAPAFYQAEIFEIVWSLWNLSRTDIDLSDPEIVRTYLPYLDHVEQHWVRGRGVGWTGNSTLEDCDTTSVAYDVLSKFGRSPDIGAVLQFEDADWFRTYFHEVGPSISTNVHVLGALKQAGYDKCHPRVRKVLEFIRSSKEPGRFCWRDKWHRSAYYTTAHLICAASNYDDALCSDAIGWILNTQRPDGSWGFFDGQATAEETAYCIQALAHWQRHSGTSLSAQISRAGGWLSQHCEPPYAPLWIAKTLYCSATVVKAAILSALRLVDESNQ
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: Rv3377c mutant is attenuated in survival inside of macrophages (Pethe et al., 2004).
COG COG1657I, under I: Lipid transport and metabolism
References
Pethe et al., 2004: Pethe K, Swenson DL, Alonso S, Anderson J, Wang C, Russell DG. Isolation of Mycobacterium tuberculosis mutants defective in the arrest of phagosome maturation. Proceedings of the National Academy of Sciences of the United States of America. 2004; 101(37); 13642-13647. [PubMed: 15340136].