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dsbB

Victor ID 2869
Gene Name dsbB
Sequence Strain (Species/Organism) Haemophilus influenzae Rd KW20
NCBI Gene ID 950809
NCBI Protein GI 16272376
Locus Tag HI0428
Genbank Accession L42023
Protein Accession NP_438589
Other Database IDs UniProtKB-ID: DSBB_HAEIN
UniRef100: UniRef100_P44707
UniRef90: UniRef90_Q4QNB7
UniRef50: UniRef50_Q4QNB7
UniParc: UPI00000512D3
EMBL: L42023
EMBL-CDS: AAC22087.1
RefSeq_NT: NC_000907.1
GenomeReviews: L42023_GR
KEGG: hin:HI0428
NMPDR: fig|71421.1.peg.402
TIGR: HI_0428
HOGENOM: HBG637909
OMA: ALYFQHV
ProtClustDB: PRK01749
BioCyc: HINF71421:HI_0428-MONOMER
Taxonomy ID 71421
Gene Starting Position 451166
Gene Ending Position 451699
Gene Strand (Orientation) +
Protein Name disulfide bond formation protein B
Protein pI 9.89
Protein Weight 19350.8
Protein Length 177
Protein Note disulfide oxidoreductase; integral membrane protein; required for perioplasmic disulfide bond formation; oxidizes DsbA protein
DNA Sequence 
>gi|16271976:451166-451699 Haemophilus influenzae Rd KW20 chromosome, complete genome
AATGCTCGCGCTATTAAAACAATTTTCTGAAAAACGTTTTGTGTGGTTTTTATTGGCTTTTTCAAGTTTA
GCCTTAGAATCCACCGCACTTTACTTCCAATATGGAATGGGCTTACAACCTTGTGTGCTCTGTGTTTATG
AACGTTTAGCAATGATTGGCTTATTTGTAGCGGGCACTATCGCATTACTTCAACCTCGCGTTTTCATACT
TCGATTAATCGCCTTGGCTTTAGGTTTATTCAGCAGTATTAAGGGCTTATTAATTTCATTTCGTCATCTT
GATTTGCAAATGAATCCAGCTCCTTGGAAACAATGTGAGTTTATTCCAAATTTTCCCGAGACTTTACCAT
TTCATCAATGGTTTCCATTTATATTTAACCCAACTGGCTCTTGTAATGAAAGCCAATGGTCATTATTTGG
TTTAACGATGGTGCAATGGCTAGTGGTTATTTTTTCACTATATGTGGTTATTCTCACATTATTGTTAATC
GCACAAGTGATTAAAACACGGAAACAAAGAAGATTATTTAACTA
Protein Sequence 
>gi|16272376|ref|NP_438589.1| disulfide bond formation protein B [Haemophilus influenzae Rd KW20]
MLALLKQFSEKRFVWFLLAFSSLALESTALYFQYGMGLQPCVLCVYERLAMIGLFVAGTIALLQPRVFIL
RLIALALGLFSSIKGLLISFRHLDLQMNPAPWKQCEFIPNFPETLPFHQWFPFIFNPTGSCNESQWSLFG
LTMVQWLVVIFSLYVVILTLLLIAQVIKTRKQRRLFN
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: dsbB mutant is attenuated in rats (Herbert et al., 2002).
COG COG1495O, under O: Posttranslational modification, protein turnover, chaperones
References
Herbert et al., 2002: Herbert MA, Hayes S, Deadman ME, Tang CM, Hood DW, Moxon ER. Signature Tagged Mutagenesis of Haemophilus influenzae identifies genes required for in vivo survival. Microbial pathogenesis. 2002; 33(5); 211-223. [PubMed: 12473436].