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lctP

Victor ID 2866
Gene Name lctP
Sequence Strain (Species/Organism) Haemophilus influenzae Rd KW20
NCBI Gene ID 950748
NCBI Protein GI 16273137
Locus Tag HI1218
Genbank Accession L42023
Protein Accession NP_439374
Other Database IDs UniProtKB-ID: Y1218_HAEIN
UniRef100: UniRef100_Q57251
UniRef90: UniRef90_Q57251
UniRef50: UniRef50_Q57251
UniParc: UPI00000512D2
EMBL: L42023
EMBL-CDS: AAC22871.1
RefSeq_NT: NC_000907.1
TCDB: 2.A.14.2.1
GenomeReviews: L42023_GR
KEGG: hin:HI1218
NMPDR: fig|71421.1.peg.1164
TIGR: HI_1218
HOGENOM: HBG457300
OMA: MNDATTW
ProtClustDB: CLSK870639
BioCyc: HINF71421:HI_1218-MONOMER
Taxonomy ID 71421
Gene Starting Position 1287583
Gene Ending Position 1289181
Gene Strand (Orientation) -
Protein Name L-lactate permease
Protein pI 9.87
Protein Weight 51924.33
Protein Length 532
Protein Note similar to GB:AE000782; putative
DNA Sequence 
>gi|16271976:1287583-1289181 Haemophilus influenzae Rd KW20 chromosome, complete genome
TTTATAGATTATAAAATAAAGGTACTAAGAACAGCGCGCCAAGTGCGGCAATGATACCGTAAATGATCAT
AGGTATAATGGTTTTCTTAATAATTGTGCCTTCTTGGTTTGAAATATTTAACACTGAACTTACCGCTACA
ATGTTATTTATACATACCATATTCCCCATTGCCCCACCAACAGATTGTAAAGCAAGAACAAGTGCGACAG
AAATGCCTGTTGTTTCTGCGGTAGAAAGTTGAACACTACCAAATGTTAGGTTGGATACGGTATTTGAACC
TGAGAAAAAGGAACCAATCGCGCCTAAGAAAGAGGAGAAAATAGTCCAGTTACTACCAGAAATTTCAGCA
AAAGTTCTACCTATAATTTTTACCATAGAATGTTCGCCACCCACTAACATTAGGTTTACCATCACTAAGG
CACCAATTAAGGCAATAAATGGATTTTTAGATTGTTGTAAACTTGATACCAAAATCTGTTTAACATTTGA
ACTGGAAATTTTAAAGAAAGGAATCGCAATTAGTACTGTAATGACAAATGGAATCAATGCGGGTACGTAA
AGAAGTTTATAGCTTGATGAAACATTTGAGCCAAAAATATTTTTTAAGCTAAAGATTAAACCTTTGCTAA
TTTCAAATAATCCTAACGAACCTAATGTGGTTGAGAACCAAATAGTTGCGTCATTCATCATTGCTTTGAA
TGGTAATTGATGAATACGAGTCACAATTAAAAATGCAATAAGTAAACCTGTCGGAAATAATGCTTTAACT
ACTTCTCCTGCACTTACCGCATTATTATCAAGGGTATTTGTTACTTTTGCTAAACCAATATTGCGATTAG
CAGCCCATACAGAAATAAATAAGCCGATTGCCCCCCCAACGAGTGATGGAAATTCGTAATTGACTTGAGC
AATCAAGAAATAAGGTACTACGCAACCCAGTACGCTAATATAGATAAATACGATGTTTTTACGAATATCA
TCCCAATTTACTAAGATACGAAGTGCTAATAATGGGATAATAAGTGCAGCAATGGAGTGTATAAATGCTG
TAATAGACCCAATTTCTAAAATCATATCTTCTGATAATTTTAAAGCACCAAAACCAAACCAAGTTGGTGT
ACCTACCGCACCAAAGGATACGGGAACTGAGTTCATAATAAGTGCCAACATCGCCACTTTTAATGGATGA
AAACCTAATCCCACTAAAATAGGTGCAGCAATTGCCGCTGGTGTACCAAAACCACTTGCTCCCTCGATCA
TAAAAGCAAACGCCCAACCAATAATCATTAATTGTGCAACGGGATTTGGATTAATATTTCCTAGCCATTT
TCGCATAATATTTGTTGCGCCTGAAATTTCAGAGAAACGGTTAAAGAGAATCGCACCAAAAATTACTGTA
ATAGGTGTTTGTACCGCAATAATTGCAGAAACAACATTTGCACTAATAGTGACAATATCTGTATTAAAGT
GTAAAAGATGAACACCCATAACTAATGTCGCAACCCAAGGTAAGGCAACATAAGAAGGTAGCGCGTTTCT
TTTTACCATAAGATAAATCAGTAAAACGATAGGAAAAATACTTAGAATAAAAGACAGCA
Protein Sequence 
>gi|16273137|ref|NP_439374.1| L-lactate permease [Haemophilus influenzae Rd KW20]
MLSFILSIFPIVLLIYLMVKRNALPSYVALPWVATLVMGVHLLHFNTDIVTISANVVSAIIAVQTPITVI
FGAILFNRFSEISGATNIMRKWLGNINPNPVAQLMIIGWAFAFMIEGASGFGTPAAIAAPILVGLGFHPL
KVAMLALIMNSVPVSFGAVGTPTWFGFGALKLSEDMILEIGSITAFIHSIAALIIPLLALRILVNWDDIR
KNIVFIYISVLGCVVPYFLIAQVNYEFPSLVGGAIGLFISVWAANRNIGLAKVTNTLDNNAVSAGEVVKA
LFPTGLLIAFLIVTRIHQLPFKAMMNDATIWFSTTLGSLGLFEISKGLIFSLKNIFGSNVSSSYKLLYVP
ALIPFVITVLIAIPFFKISSSNVKQILVSSLQQSKNPFIALIGALVMVNLMLVGGEHSMVKIIGRTFAEI
SGSNWTIFSSFLGAIGSFFSGSNTVSNLTFGSVQLSTAETTGISVALVLALQSVGGAMGNMVCINNIVAV
SSVLNISNQEGTIIKKTIIPMIIYGIIAALGALFLVPLFYNL
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: lctP mutant is attenuated in rats (Herbert et al., 2002).
COG COG1620C, under C: Energy production and conversion
References
Herbert et al., 2002: Herbert MA, Hayes S, Deadman ME, Tang CM, Hood DW, Moxon ER. Signature Tagged Mutagenesis of Haemophilus influenzae identifies genes required for in vivo survival. Microbial pathogenesis. 2002; 33(5); 211-223. [PubMed: 12473436].