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amiD

Victor ID 286
Gene Name amiD
Sequence Strain (Species/Organism) Mycobacterium tuberculosis H37Rv
NCBI Gene ID 888064
NCBI Protein GI 15610511
Locus Tag Rv3375
Protein Accession NP_217892.1
Other Database IDs UniProtKB-ID: AMI4_MYCTU
UniRef100: UniRef100_P63497
UniRef90: UniRef90_P63497
UniRef50: UniRef50_P63497
UniParc: UPI0000125976
EMBL: BX842582
EMBL: AE000516
EMBL-CDS: CAA15760.1
EMBL-CDS: AAK47821.1
RefSeq_NT: NC_000962.2
RefSeq_NT: NC_002755.2
EnsemblGenome: EBMYCG00000001043
EnsemblGenome_TRS: EBMYCT00000001043
EnsemblGenome_PRO: EBMYCP00000001043
EnsemblGenome: EBMYCG00000071365
EnsemblGenome_TRS: EBMYCT00000071370
EnsemblGenome_PRO: EBMYCP00000069429
GenomeReviews: AE000516_GR
GenomeReviews
Taxonomy ID 83332
Gene Starting Position 3788620
Gene Ending Position 3790047
Gene Strand (Orientation) +
Protein Name PROBABLE AMIDASE AMID (ACYLAMIDASE) (ACYLASE)
DNA Sequence 
>gi|57116681:3788620-3790047 Mycobacterium tuberculosis H37Rv, complete genome
CATGACCGATGCTGACAGTGCGGTCCCTCCCCGACTCGACGAGGACGCGATCTCGAAACTCGAGCTGACC
GAGGTCGCCGACCTGATCCGCACCCGGCAACTGACGTCGGCAGAAGTGACCGAGTCGACGCTGCGGCGTA
TCGAAAGGCTTGACCCCCAGCTGAAGAGCTACGCCTTCGTCATGCCGGAAACTGCGCTAGCGGCGGCACG
TGCCGCCGACGCCGACATCGCGCGCGGCCACTACGAGGGTGTCCTGCACGGCGTACCGATCGGCGTGAAG
GATCTCTGCTACACGGTCGACGCCCCGACCGCGGCCGGCACCACCATCTTTCGTGACTTTCGCCCGGCAT
ACGACGCGACGGTTGTCGCGAGGTTGCGCGCGGCCGGCGCGGTGATCATCGGCAAGCTGGCCATGACGGA
GGGGGCCTATCTCGGCTATCACCCCAGTCTGCCGACCCCGGTCAATCCCTGGGACCCGACAGCGTGGGCG
GGCGTGTCCTCGAGCGGCTGCGGCGTGGCCACCGCGGCGGGATTGTGCTTCGGCTCGATCGGGTCGGACA
CCGGGGGGTCGATTCGCTTTCCGACGAGCATGTGCGGCGTCACCGGGATCAAACCGACGTGGGGCCGGGT
CAGCCGTCACGGCGTCGTCGAACTTGCGGCAAGCTACGACCACGTCGGGCCGATCACCCGTAGCGCTCAC
GATGCGGCGGTATTGCTCAGTGTCATAGCGGGATCCGATATCCACGATCCCTCGTGCTCGGCGGAGCCCG
TTCCGGACTATGCCGCCGACCTCGCCTTGACACGGATTCCGCGTGTCGGGGTGGACTGGTCGCAGACGAC
GTCGTTTGACGAGGACACCACGGCGATGCTGGCCGATGTCGTCAAAACGCTCGACGACATCGGATGGCCC
GTCATCGACGTCAAGCTGCCCGCGCTTGCGCCGATGGTGGCAGCGTTCGGAAAAATGCGCGCGGTCGAAA
CGGCGATCGCGCATGCCGACACCTACCCGGCGCGCGCCGACGAGTACGGGCCGATCATGCGCGCAATGAT
CGACGCCGGACACAGGCTGGCTGCGGTGGAATATCAGACGCTGACCGAGCGGCGTCTGGAATTCACGCGA
TCGCTGCGTCGCGTGTTCCACGACGTGGACATCCTGCTGATGCCCAGCGCCGGAATTGCCTCGCCCACAC
TGGAAACCATGCGCGGGCTCGGACAAGACCCGGAGCTGACCGCCAGACTGGCGATGCCGACAGCACCGTT
CAACGTCAGCGGTAATCCCGCGATATGCCTACCGGCGGGAACGACGGCGCGCGGAACGCCGCTCGGCGTC
CAGTTCATCGGCCGTGAATTCGACGAGCACTTGCTCGTCCGAGCCGGCCACGCATTTCAGCAAGTCACCG
GGTATCATCGCCGACGCCCGCCGGTGTG
Protein Sequence 
>gi|15610511|ref|NP_217892.1| amidase [Mycobacterium tuberculosis H37Rv] MTDADSAVPPRLDEDAISKLELTEVADLIRTRQLTSAEVTESTLRRIERLDPQLKSYAFVMPETALAAARAADADIARGHYEGVLHGVPIGVKDLCYTVDAPTAAGTTIFRDFRPAYDATVVARLRAAGAVIIGKLAMTEGAYLGYHPSLPTPVNPWDPTAWAGVSSSGCGVATAAGLCFGSIGSDTGGSIRFPTSMCGVTGIKPTWGRVSRHGVVELAASYDHVGPITRSAHDAAVLLSVIAGSDIHDPSCSAEPVPDYAADLALTRIPRVGVDWSQTTSFDEDTTAMLADVVKTLDDIGWPVIDVKLPALAPMVAAFGKMRAVETAIAHADTYPARADEYGPIMRAMIDAGHRLAAVEYQTLTERRLEFTRSLRRVFHDVDILLMPSAGIASPTLETMRGLGQDPELTARLAMPTAPFNVSGNPAICLPAGTTARGTPLGVQFIGREFDEHLLVRAGHAFQQVTGYHRRRPPV
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: attenuated in mice (Sassetti and Rubin, 2003).
COG COG0154J, under J: Translation, ribosomal structure and biogenesis
References
Sassetti and Rubin, 2003: Sassetti CM, Rubin EJ. Genetic requirements for mycobacterial survival during infection. Proceedings of the National Academy of Sciences of the United States of America. 2003; 100(22); 12989-12994. [PubMed: 14569030].