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dsbA from Haemophilus influenzae Rd KW20

Victor ID 2858
Gene Name dsbA from Haemophilus influenzae Rd KW20
Sequence Strain (Species/Organism) Haemophilus influenzae Rd KW20
NCBI Gene ID 950165
NCBI Protein GI 30995432
Locus Tag HI1215
Protein Accession NP_439371.2
Other Database IDs UniProtKB-ID: Y1215_HAEIN
UniRef100: UniRef100_P44128
UniRef90: UniRef90_P44128
UniRef50: UniRef50_P44128
UniParc: UPI000013A435
EMBL: L42023
EMBL-CDS: AAC22868.1
RefSeq_NT: NC_000907.1
GenomeReviews: L42023_GR
KEGG: hin:HI1215
NMPDR: fig|71421.1.peg.1161
TIGR: HI_1215
HOGENOM: HBG297095
OMA: FFDYDCR
ProtClustDB: CLSK870008
BioCyc: HINF71421:HI_1215-MONOMER
Taxonomy ID 71421
Gene Starting Position 1283129
Gene Ending Position 1283824
Gene Strand (Orientation) +
Protein Name thiol-disulfide interchange protein
DNA Sequence 
>gi|16271976:1283129-1283824 Haemophilus influenzae Rd KW20, complete genome
AATGAAATTAAAAGGGTTATTGGCATTTTGTTTGCTTTTTTTATCGTCGTTTGTTTTAGCAGAAGTCAAT
CAGAAAGAATTTTCAGTGCAAAATTCTCCGCACTTGCCATCACGGGACACAATTTATTTTGAAGACGGGC
GTGATTATTTTTCTTATAAAGAACCTATTGAACAAGCGTCTCGAACCGATAAAAAAATCCGCATTCAATT
CTTTTTTGATTACGATTGTCGAGTATGTTCTTCAGCGCAGGATATTTTAGAGCTTTATAGCCAAATACGC
ACATATAAAGTTGCGTTGGAACAATATCCTATTGCAACTGCCGATAACCAGTTTAGCGCACGCATTTTTT
ATACTTTGCAAGCATTAAGTGCGGGGGAATTATCTAATGTTTTATTATTTGAAACTTCAGAAAAATCCCG
TTATACAGAATTGTCTACATCAAATAAAATTCAGCAATGGGCGGAAGAACAAGGGTTAGATAAACAGTTA
TTTATTCAAACTGAAAATTCACAAAGCGTAAAAGAACAAATTCAAAATGCGATTGAATTGACGGAAGAAT
ATGGTGTGTTTACCTATCCTTACGTTGTTATTGGGGGAAAATATGTACTCACTGCGAGTACGCTTTATAA
CGATGATTATAGCGTAGCGGTGTTAGATTTTTTGGTAAATAAAATAGAACAGGAACAAAAACAATG
Protein Sequence 
>gi|30995432|ref|NP_439371.2| thiol-disulfide interchange protein [Haemophilus influenzae Rd KW20] MKLKGLLAFCLLFLSSFVLAEVNQKEFSVQNSPHLPSRDTIYFEDGRDYFSYKEPIEQASRTDKKIRIQFFFDYDCRVCSSAQDILELYSQIRTYKVALEQYPIATADNQFSARIFYTLQALSAGELSNVLLFETSEKSRYTELSTSNKIQQWAEEQGLDKQLFIQTENSQSVKEQIQNAIELTEEYGVFTYPYVVIGGKYVLTASTLYNDDYSVAVLDFLVNKIEQEQKQ
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: dsbA mutant is attenuated in mice (Rosadini et al., 2008).
COG COG1651O, under O: Posttranslational modification, protein turnover, chaperones
References
Rosadini et al., 2008: Rosadini CV, Wong SM, Akerley BJ. The periplasmic disulfide oxidoreductase DsbA contributes to Haemophilus influenzae pathogenesis. Infection and immunity. 2008; 76(4); 1498-1508. [PubMed: 18212083].