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ompA

Victor ID 2857
Gene Name ompA
Sequence Strain (Species/Organism) Haemophilus influenzae Rd KW20
NCBI Gene ID 950124
NCBI Protein GI 16273088
Locus Tag HI1164
Genbank Accession L42023
Protein Accession NP_439322
Other Database IDs UniProtKB-ID: OMP51_HAEIN
UniRef100: UniRef100_P43840
UniRef90: UniRef90_P43840
UniRef50: UniRef50_P45996
UniParc: UPI0000040A52
EMBL: L42023
EMBL-CDS: AAC22819.1
RefSeq_NT: NC_000907.1
GenomeReviews: L42023_GR
KEGG: hin:HI1164
NMPDR: fig|71421.1.peg.1117
TIGR: HI_1164
HOGENOM: HBG741096
OMA: DDNEAQK
ProtClustDB: CLSK808491
BioCyc: HINF71421:HI_1164-MONOMER
Taxonomy ID 71421
Gene Starting Position 1235300
Gene Ending Position 1236361
Gene Strand (Orientation) +
Protein Name outer membrane protein P5
Protein pI 9.95
Protein Weight 34469.99
Protein Length 353
Protein Note similar to GB:L20309 SP:P38368
DNA Sequence 
>gi|16271976:1235300-1236361 Haemophilus influenzae Rd KW20 chromosome, complete genome
AATGAAAAAAACTGCAATCGCATTAGTAGTTGCTGGTTTAGCAGCAGCTTCAGTAGCTCAAGCAGCTCCA
CAAGAAAACACTTTCTACGCTGGCGTTAAAGCTGGTCAAGCATCTTTTCACGATGGACTTCGTGCTCTAG
CTCGTGAATATAAAGTAGGTTATCACCGTAATTCTTTCACTTATGGTGTATTCGGTGGTTATCAAATTTT
AAATCAAAATAACTTAGGTTTAGCGGTTGAATTAGGTTACGACGATTTCGGTCGTGCCAAAGGTCGTGAA
AAAGGTAAAACTGTTGTTAAACACACTAACCACGGTACTCACTTAAGCTTAAAAGGTAGCTACGAAGTAT
TAGAAGGTTTAGATGTTTATGGTAAAGCAGGTGTTGCTTTAGTTCGTTCTGACTATAAATTATACAATGA
AAATAGTAGTACTCTTAAAAAACTAGGCGAACATCACAGAGCACGTGCCTCTGGTTTATTTGCAGTAGGT
GCAGAATACGCAGTATTACCAGAATTAGCAGTTCGTTTAGAATACCAATGGCTAACTCGCGTAGGTAAAT
ACCGCCCTCAAGATAAACCAAATACCGCACTTAACTACAACCCTTGGATTGGTTCTATCAATGCGGGTAT
TTCTTACCGTTTTGGTCAAGGCGCAGCACCAGTTGTTGCAGCACCTGAAGTTGTAAGCAAAACTTTCAGC
TTAAACTCTGATGTAACTTTCGCATTTGGTAAAGCAAACTTAAAACCTCAAGCACAAGCAACATTAGACA
GCATCTATGGCGAAATGTCACAAGTTAAAAGTGCAAAAGTAGCTGTTGCTGGTTACACTGACCGTATTGG
TTCTGACGCGTTCAACGTAAAACTTTCTCAAGAACGTGCAGATTCAGTAGCTAACTACTTTGTTGCTAAA
GGTGTTGCAGCAGACGCAATCTCTGCAACTGGCTACGGTAAAGCAAACCCAGTAACTGGTGCAACTTGTG
ACCAAGTTAAGGGTCGTAAAGCGCTTATCGCTTGTTTTGCTCCAGACCGTCGTGTAGAAATCGCGGTAAA
CGGTACTAAATA
Protein Sequence 
>gi|16273088|ref|NP_439322.1| outer membrane protein P5 [Haemophilus influenzae Rd KW20]
MKKTAIALVVAGLAAASVAQAAPQENTFYAGVKAGQASFHDGLRALAREYKVGYHRNSFTYGVFGGYQIL
NQNNLGLAVELGYDDFGRAKGREKGKTVVKHTNHGTHLSLKGSYEVLEGLDVYGKAGVALVRSDYKLYNE
NSSTLKKLGEHHRARASGLFAVGAEYAVLPELAVRLEYQWLTRVGKYRPQDKPNTALNYNPWIGSINAGI
SYRFGQGAAPVVAAPEVVSKTFSLNSDVTFAFGKANLKPQAQATLDSIYGEMSQVKSAKVAVAGYTDRIG
SDAFNVKLSQERADSVANYFVAKGVAADAISATGYGKANPVTGATCDQVKGRKALIACFAPDRRVEIAVN
GTK
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: ompA mutant had reduced adherence to human oropharyngeal cells in vitro, augmented clearance from the tympanum post-transbullar inoculation, and significantly reduced induction of OM post-intranasal inoculation in a chinchilla model compared to the wild type (Sirakova et al., 1994).
COG COG2885M, under M: Cell wall/membrane/envelope biogenesis
References
Sirakova et al., 1994: Sirakova T, Kolattukudy PE, Murwin D, Billy J, Leake E, Lim D, DeMaria T, Bakaletz L. Role of fimbriae expressed by nontypeable Haemophilus influenzae in pathogenesis of and protection against otitis media and relatedness of the fimbrin subunit to outer membrane protein A. Infection and immunity. 1994; 62(5); 2002-2020. [PubMed: 7909539].