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emrA

Victor ID 2853
Gene Name emrA
Sequence Strain (Species/Organism) Haemophilus influenzae Rd KW20
NCBI Gene ID 949904
NCBI Protein GI 16272836
Locus Tag HI0898
Genbank Accession L42023
Protein Accession NP_439059
Other Database IDs UniProtKB-ID: EMRA_HAEIN
UniRef100: UniRef100_P44928
UniRef90: UniRef90_P44928
UniRef50: UniRef50_P44928
UniParc: UPI00000512C6
EMBL: L42023
EMBL-CDS: AAC22558.1
RefSeq_NT: NC_000907.1
GenomeReviews: L42023_GR
KEGG: hin:HI0898
NMPDR: fig|71421.1.peg.865
TIGR: HI_0898
HOGENOM: HBG624965
OMA: VRIKLDP
ProtClustDB: CLSK808463
BioCyc: HINF71421:HI_0898-MONOMER
Taxonomy ID 71421
Gene Starting Position 954176
Gene Ending Position 955348
Gene Strand (Orientation) -
Protein Name multidrug resistance protein A
Protein pI 8.91
Protein Weight 40085.31
Protein Length 390
Protein Note similar to GB:M86657 SP:P27303 PID:145835 GB:U00096 PID:1789041; putative
DNA Sequence 
>gi|16271976:954176-955348 Haemophilus influenzae Rd KW20 chromosome, complete genome
CTTAATGGCTGTTTTGCTGAATGATAGATTCAATCAAATTTTCTACCGCACTTTCATCATATTTAAGTGT
ATCAGTAGAAAATAACGTTTTCGGTTCTGTTTTTTCTCGTAGCATTGCGCCTGATGAATCTGAAATTCTT
ACTTTTGCCGTTGCAGAAAGACCAATTCTCAATGGCGTTTCTGTAAATTGTTGTGGATCTAATTTAATTC
GCACAGGTACGCGTTGCACCACTTTAATCCAGTTACCCGTAGCATTTTGTGAAGGCAAAAGAGAAAATGC
ATTGCCAGTCCCCATTTCAATACCATTTATCACGCCATCAAATTCTTTATTTTTACCGTATAAATCAAAA
TGGATTTTTACTGGCTGACCAATGCGCATATTCGTTAATTGGGTTTCTTTGAAGTTAGCTTCTAGCCACA
TTTGTTCATTAGATACCACTGCCATTAACGCGCCACCCACTGAAACGGCTTGCCCAACTTGAACATTACG
ACGCGCCACATAGCCATCAATTGGACTTCTAATTTTTGTACGTTGCAAATTTAACCAAGCCTGTTTAAGC
GAGTTTATCGCATTCTGTATTTGCGGTTGTTCACGTAATGGAACGTTACGCAATAAAGCCTGATTAGCAG
CCAATTGATTTTTAGAGGCATTTAAATTTGCTTTGGCAAGCTCGACAGCTTCTTTTGCGTGTTGGAAAGA
TTCTTTATCAATCGCACCCATTTTTTCAAGTTGAACTCGGCGCGCCAAATTGCCTTGAGCTTGAGCTAAA
GAAATTTCATTGGCGTGCACAGCTGATTGCAATTGCTGCACAGTGAAACCCAGTTGTTCTACCTGACGTA
CAGCATTGGCGAGATTGCTTTTGGCCTGTTCGAAACTAAGTTTCGCATTGGTATCATCCAATTCAACTAG
AATATCACCTGCATGGACTTTATCCATATTGTCTGCATTAATCTTCGCTACATTACCTGCAACTTGTGAT
GATACCATTACTTGATTTCCACCCACATAAGCATCTTCTGTTTCTTCAAAATCCTTCAAGAAGAAAAACC
AATACAAAGCACAAGCAATACCAATAATAAGCAGGAGAAGAATAAAAATGCTTAAGCCTTTTTTACGGTC
AGTTTTATTTGATACAGATTTAGTTGATGGGTTTTCAGTTGCAATTTGCGTCA
Protein Sequence 
>gi|16272836|ref|NP_439059.1| multidrug resistance protein A [Haemophilus influenzae Rd KW20]
MTQIATENPSTKSVSNKTDRKKGLSIFILLLLIIGIACALYWFFFLKDFEETEDAYVGGNQVMVSSQVAG
NVAKINADNMDKVHAGDILVELDDTNAKLSFEQAKSNLANAVRQVEQLGFTVQQLQSAVHANEISLAQAQ
GNLARRVQLEKMGAIDKESFQHAKEAVELAKANLNASKNQLAANQALLRNVPLREQPQIQNAINSLKQAW
LNLQRTKIRSPIDGYVARRNVQVGQAVSVGGALMAVVSNEQMWLEANFKETQLTNMRIGQPVKIHFDLYG
KNKEFDGVINGIEMGTGNAFSLLPSQNATGNWIKVVQRVPVRIKLDPQQFTETPLRIGLSATAKVRISDS
SGAMLREKTEPKTLFSTDTLKYDESAVENLIESIIQQNSH
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: emrA mutant is attenuated in rats (Herbert et al., 2002).
COG COG1566V, under V: Defense mechanisms
References
Herbert et al., 2002: Herbert MA, Hayes S, Deadman ME, Tang CM, Hood DW, Moxon ER. Signature Tagged Mutagenesis of Haemophilus influenzae identifies genes required for in vivo survival. Microbial pathogenesis. 2002; 33(5); 211-223. [PubMed: 12473436].