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arcA

Victor ID 2851
Gene Name arcA
Sequence Strain (Species/Organism) Haemophilus influenzae Rd KW20
NCBI Gene ID 949839
NCBI Protein GI 16272824
Locus Tag HI0884
Genbank Accession L42023
Protein Accession NP_439045
Other Database IDs UniProtKB-ID: ARCA_HAEIN
UniRef100: UniRef100_P44918
UniRef90: UniRef90_P44918
UniRef50: UniRef50_P44918
UniParc: UPI0000125D8D
EMBL: L42023
EMBL-CDS: AAC22542.1
RefSeq_NT: NC_000907.1
GenomeReviews: L42023_GR
KEGG: hin:HI0884
TIGR: HI_0884
HOGENOM: HBG753323
OMA: FENHAIN
ProtClustDB: PRK11173
BioCyc: HINF71421:HI_0884-MONOMER
Taxonomy ID 71421
Gene Starting Position 936510
Gene Ending Position 937220
Gene Strand (Orientation) -
Protein Name two-component response regulator
Protein pI 6.35
Protein Weight 26431.33
Protein Length 236
Protein Note similar to SP:P03026 GB:L34010 GB:M10044 PID:1790863
DNA Sequence 
>gi|16271976:936510-937220 Haemophilus influenzae Rd KW20 chromosome, complete genome
TTTATTCAATATCTCCACAAAAACGATAGCCTTCTCCATGTATAGTCATAATGATATTTGGAGTATTGGG
ATGATCTTCAAAATGTTTTCTGATACGTCGAATTGTGACATCTACGGTACGATCCTGAGGTTTTAACTCT
CGTCCGGTCATTTTTTTCAGCAATTCTTCGCGCGTTTGCAATTTTCCTGGATTTTCACAGAAATGTAACA
TTGCACGAAATTCACTGCGAGGAAGTTTGAATTCTTGTCCTTCTGGTGTAATTAAACTGTGGCTATTTAG
GTCTAATTTCCAACCATTAAAACGATAGAATTCTCGACCAAATGTATTTTCTTTTTCTTGATGCGGCATT
GCACGATGCAATAGATTACGTGCGCGGATAGTCAGTTCTCTAGGGTTAAAAGGCTTAGTCAAATAGTCAT
CGGCACCAATTTCCAAACCTAAAATTTTATCCACTTCATTATCTCGACCAGTTAAAAAAATAAGAGGTAA
GCTTAATTCTTCACGGAGTTCTCTTGCCAATAATAAGCCGTTTTTGCCTGGTAAATTAATATCCATCACA
ACCAAATTAATATTATGATTTGCCAATATATGATGCATTTCAACACCATTTTCTGCTTCAAACACATCAT
ATCCTTCCGCTTCAAAAATCCCTTTAAGCGTATTTCGAGTGACAATTTCATCTTCAACAACGAGAATTTT
TGGAGTAGTCA
Protein Sequence 
>gi|16272824|ref|NP_439045.1| two-component response regulator [Haemophilus influenzae Rd KW20]
MTTPKILVVEDEIVTRNTLKGIFEAEGYDVFEAENGVEMHHILANHNINLVVMDINLPGKNGLLLARELR
EELSLPLIFLTGRDNEVDKILGLEIGADDYLTKPFNPRELTIRARNLLHRAMPHQEKENTFGREFYRFNG
WKLDLNSHSLITPEGQEFKLPRSEFRAMLHFCENPGKLQTREELLKKMTGRELKPQDRTVDVTIRRIRKH
FEDHPNTPNIIMTIHGEGYRFCGDIE
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: arcA mutant is attenuated in mice (De et al., 2003).
COG COG0745TK, under T: Signal transduction mechanisms; K: Transcription
References
De et al., 2003: De Souza-Hart JA, Blackstock W, Di Modugno V, Holland IB, Kok M. Two-component systems in Haemophilus influenzae: a regulatory role for ArcA in serum resistance. Infection and immunity. 2003; 71(1); 163-172. [PubMed: 12496162].