Search: for Help
About
Introduction
Statistics
Your PHIDIAS
Register or Login
Philert
Submission
Curated Data
Victors
BBP (Brucella)
Phinfo
Phinet
HazARD
Data Analysis
Phigen
Pacodom
BLAST
Help & Documents
Documents
FAQs
Links
Acknowledgements
Disclaimer
Contact Us
UMMS Logo

oapA from Haemophilus influenzae Rd KW20

Victor ID 2849
Gene Name oapA from Haemophilus influenzae Rd KW20
Sequence Strain (Species/Organism) Haemophilus influenzae Rd KW20
NCBI Gene ID 949701
NCBI Protein GI 16272604
Locus Tag HI0661
Protein Accession NP_438821.1
Other Database IDs UniProtKB-ID: HGP2_HAEIN
UniRef100: UniRef100_P44809
UniRef90: UniRef90_O87296
UniRef50: UniRef50_Q9KIV2
UniParc: UPI000012C6DB
EMBL: L42023
EMBL-CDS: AAC22319.1
RefSeq_NT: NC_000907.1
GenomeReviews: L42023_GR
KEGG: hin:HI0661
TIGR: HI_0661
HOGENOM: HBG296580
OMA: KWSLNYQ
ProtClustDB: CLSK2518365
BioCyc: HINF71421:HI_0661-MONOMER
Taxonomy ID 71421
Gene Starting Position 703647
Gene Ending Position 706679
Gene Strand (Orientation) -
Protein Name hemoglobin-binding protein
DNA Sequence 
>gi|16271976:703647-706679 Haemophilus influenzae Rd KW20, complete genome
TTTAAAATTCAAACTGAACTGACATTTTATAATTTCTACCTGGTGCGTAGAAGCGGTTAATGCCTAATCC
TGTTGATTGATCTATAACATTACTTGTTCCAAATGAACGAATTGAACGAGCAGAATCCCAAGTAATGTAT
TTACGGTTTGTAAGATTATATACACCAGCTCTTATGGTTAAATTTTTAATTGGTTGTACATATCCAATTA
AATCTAGAATAGTATAAGATTTGCTTCTCCATTTAATTGTGCTGTCTTTTTTATTTTCTTCTTTATAGAA
CATATTATAAGTATCTTCTGGATTTTTACTTGCTACATGTGTCGTATAGAAATCGAAACCAAATTTATGA
TTTGGATGATCATATCCTAAACCATATACCATAGTTCTAGGCTGAATTGCATTCATAGGAATATTGCCAT
TCATTCTGCCTTTTTGATAGGTATATTTATAGCTTAGGTTAAATCCATCCATAAATTTTGCCATTTTACC
AAGGAATACTTTTGAATTAATTTCAATACCTTTTAAAGACGCATTATCTCTATTTATATTTTGATAAAGA
GAAAATGGTAATGTTTCACCTCTTCCAGAGCCGCCTACTTTAAAAGTTTCTTGCTTTTTAAATATTAGGT
CAATAAAGTTTTTATAGTTAGTTTTAAACAGACTTGTCGAGATAAATCCCCAATCATCATTATGTAATGT
GAAAGCAATTTCTTTGGTTTTTGCTATTTCTGGTTTTAAATCAGTATTTGGCAAAATAGTGAAATCAGGG
TGTTTAAAGGTGAAATACATTTCATCTGAAGTTGGTGTTCTAAAACCTTTAGAATATTTTAGTTGTAAAC
GAAGAAAACTCGTTGGATCAATGGTTGAAACAAAACTATAAGAATGTGCTTTATATTTTTTGTTCTGTTT
GGCGATATAGTCAATATTTTGTTGTACATTTTCCTTAACTTTATTAGGATCTGAATTTGAATTGTTTGGT
AATGGAATAAATAATCCTTTCACAATATCATCGGGTAATTTGGGTGTGATACCGTGTTTATATTTTGGTT
GATAATGGATATTGTCATAACGATAACCCAAATCAAAAGATAAATAATCAGTTATAACAAAATTATCAAA
GAGATAGACTGATTTTCCTGTTGTTTTAATGGGTAATAAGTAAGAAAATTCAGGATCAACTCGAGGACAA
AGGTTAGCATTCCACTCATAAGTCGTTGCACAAGTGTGAGGTTTTCCAGTCCAAGAATCCTCACCAAGCG
TAGGTGTTGCCCACCATTGCACATCAGAAGCATCGTTGCCAGCACGATTAACCATGCGCTTCATCGCGGT
ATTATATGATCCACCATATTGTAGATTATGTTCAATATGCCAAATTTTGAAGTCTTTGGTTAAATCTAAA
TTTAATTGTTGGGTGTTGGTGTCCAAATCTCTCTCTTGCCAGAGGCGTTCTAAATAACCAGGTGAAGAGG
GAAGAATAGATTTTATTTTCCTATCATTATCCTTTATTTTAGCGAATTTTTTGCCATTTAATTCTTTTAT
TTCAAGGTCAACTTCTTTCCATTTTCCATCATAGCCATAATAATTGTTACCTTTAAAAACTTTTATTTTT
GCGTTATTTTCACAATTAAATATTGAACAATCATACCAAGTGTCAGAGGGGTTGTTTAGGACTAGTTTAT
CGTCTATTACTCTCTTATCAGTATCAATAAATTTCTTGAAGTCATAGGTTTTATCACTACTCTTAGCTGT
ATTGTTTTTTTCCTCAAATTGAAGGTCTGAACCATCTCGACGTGTTATTTTCCCATTTGTTACTTTTAGT
CCCGTAGGATTGTCTGTGCCTTCACAATGTCTTACACCAGCATCACAATACTCATCTGTGCGTGCACGAG
TTTTAATACGTTGATCAGAATAAGTGAGTTTTAGCGTATCCCAAAATGGAGTTTGAGAGAAATTTTCATA
ACTAAATGAAATATTACGTCTCTTTGTTTTATCATTGGTGTGTCTAGAATCAACTTCAGGGGTTTCATTA
CCACTACGTTGATATTTTAATGTATAGGATAAATCTTGCCCACGAGAACGATGTTCATATAAATCAGCGG
CAAAGGTAAAACGATGATTTTCTGTAGGATTGAAAGATAATTTTAATAATGTACTATCTTGTTCAATTTT
ATATGGATCTGCTTTTTCTCTTTTTTTACCTTGAATTTTATCGTTATAATTTTTATAACCATAGTTCTCA
AGTTCATGCCCATTTCTGCTTGTTGTAACCACTAGCACATCGAACTTTTTATAACGTCCTGCAAGAGTAA
GGGTATCGAATGATTGATTATTTTCCGTAGCGTATCCCTTTTTGTAACTTACATAGTAATCCTTGTTTAT
GAGATAATCTCTCGCATCTTTTGTTTTATAAATTACAGAACCACCTAAGGAACCACTACCATTCTTAATA
GAATCAGCCCCTTTTGTGATATTTACTTCTTTTAAGGTTTCAATTTCTGCACCATTACGCGTGTTATTGA
AATTACCATAACCTTCAAAAAGCTCTTTAAAGCCTTGAGAAGATAAGGTTTCAGCTTGACGTAATCCATC
AATATTAATCGCTACACGATTTTCATCTACACCACGAATGGCAAAACCGCTTTGCCCAAAACGTCCAGCT
TCAACAACAGTAACGCCCGTTTCGTATTTAACGATGTCTTTAATGTTGTTTGCTTGTTCTCTTTCCAGCG
TTTTAGCTGTTTTTACCGTTTCAGCAATTTTTGGTGGTGTTTTTGTATCACTATTTTCGGTAGAACCAGA
TACATTTATTTGTTCTAGTTGTTCAGAAACATTACTATTTTGGTTGGTTGGTTGGTTGGTTGGTTGGTTG
GTTGGTTGGTTGGTTGGTTGGTTGGTTGGTTGGTTGGTTGGTTGGTTGGTTGAGCTGCATAAGCAACACC
TGCCGTTAGCCCAAGCATAACGGAATAGGCAAGCACGTTCTAATCTAAAATTGGTCATATTTAATCCCAT
AAAAAAAATAATAATAATTCTCA
Protein Sequence 
>gi|16272604|ref|NP_438821.1| hemoglobin-binding protein [Haemophilus influenzae Rd KW20] MRIIIIFFMGLNMTNFRLERACLFRYAWANGRCCLCSSTNQPTNQPTNQPTNQPTNQPTNQPTNQNSNVSEQLEQINVSGSTENSDTKTPPKIAETVKTAKTLEREQANNIKDIVKYETGVTVVEAGRFGQSGFAIRGVDENRVAINIDGLRQAETLSSQGFKELFEGYGNFNNTRNGAEIETLKEVNITKGADSIKNGSGSLGGSVIYKTKDARDYLINKDYYVSYKKGYATENNQSFDTLTLAGRYKKFDVLVVTTSRNGHELENYGYKNYNDKIQGKKREKADPYKIEQDSTLLKLSFNPTENHRFTFAADLYEHRSRGQDLSYTLKYQRSGNETPEVDSRHTNDKTKRRNISFSYENFSQTPFWDTLKLTYSDQRIKTRARTDEYCDAGVRHCEGTDNPTGLKVTNGKITRRDGSDLQFEEKNNTAKSSDKTYDFKKFIDTDKRVIDDKLVLNNPSDTWYDCSIFNCENNAKIKVFKGNNYYGYDGKWKEVDLEIKELNGKKFAKIKDNDRKIKSILPSSPGYLERLWQERDLDTNTQQLNLDLTKDFKIWHIEHNLQYGGSYNTAMKRMVNRAGNDASDVQWWATPTLGEDSWTGKPHTCATTYEWNANLCPRVDPEFSYLLPIKTTGKSVYLFDNFVITDYLSFDLGYRYDNIHYQPKYKHGITPKLPDDIVKGLFIPLPNNSNSDPNKVKENVQQNIDYIAKQNKKYKAHSYSFVSTIDPTSFLRLQLKYSKGFRTPTSDEMYFTFKHPDFTILPNTDLKPEIAKTKEIAFTLHNDDWGFISTSLFKTNYKNFIDLIFKKQETFKVGGSGRGETLPFSLYQNINRDNASLKGIEINSKVFLGKMAKFMDGFNLSYKYTYQKGRMNGNIPMNAIQPRTMVYGLGYDHPNHKFGFDFYTTHVASKNPEDTYNMFYKEENKKDSTIKWRSKSYTILDLIGYVQPIKNLTIRAGVYNLTNRKYITWDSARSIRSFGTSNVIDQSTGLGINRFYAPGRNYKMSVQFEF
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: oapA mutant has significantly reduced binding to Chang epithelial cells than the wild type (Prasadarao et al., 1999).
COG COG1629P, under P: Inorganic ion transport and metabolism
References
Prasadarao et al., 1999: Prasadarao NV, Lysenko E, Wass CA, Kim KS, Weiser JN. Opacity-associated protein A contributes to the binding of Haemophilus influenzae to chang epithelial cells. Infection and immunity. 1999; 67(8); 4153-4160. [PubMed: 10417187].