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licD

Victor ID 2838
Gene Name licD
Sequence Strain (Species/Organism) Haemophilus influenzae 86-028NP
NCBI Gene ID 3430833
NCBI Protein GI 68249945
Locus Tag NTHI1594
Genbank Accession CP000057
Protein Accession YP_249057
Other Database IDs UniProtKB-ID: Q4QKQ0_HAEI8
UniRef100: UniRef100_Q4QKQ0
UniRef90: UniRef90_P14184
UniRef50: UniRef50_P14184
UniParc: UPI000053E245
EMBL: CP000057
EMBL-CDS: AAX88397.1
RefSeq_NT: NC_007146.2
GenomeReviews: CP000057_GR
KEGG: hit:NTHI1594
eggNOG: COG3475
HOGENOM: HBG495239
OMA: WFQETHE
ProtClustDB: CLSK808536
BioCyc: HINF281310:NTHI1594-MONOMER
Taxonomy ID 281310
Gene Starting Position 1484395
Gene Ending Position 1485192
Gene Strand (Orientation) -
Protein Name phosphorylcholine transferase
Protein pI 8.61
Protein Weight 31158.98
Protein Length 265
Protein Note Similar to: HI1540, LICD_HAEIN
DNA Sequence 
>gi|162960935:1484395-1485192 Haemophilus influenzae 86-028NP chromosome, complete genome
CTTACAAAATATACGCTTCTTGAATATGATGTGGCTTTTGGTCTTCTTCTGGTGGAAGCTTCATATAATC
TCCATAATATTGCGTTAAGTGTTCGTGATATCCATTCATTACTTGAAATTGTCGTCCTTCAAATTCTTTA
TAAACAATGTGATTAAAATATTCTTTCGGCATATAAGATTTTTGCCAACCACCGTAGTCAGATAATACAA
GACCAATATAATCGCATTGTTTTATCGGATATTTTATTTGGAATTGTGCTAAATTTTTTTGCATTTTGGA
AAATAAAAAGTGGCTTAATTTACCAAGTATCGTTCTTTGCAAAGTATTTTCTTTTGATCTTAACCATCTT
TTCTTACAAGAAGAAAATCGAAGTTTAATTCTTCGGTGCTTTTTCATCAGTGGGTAAATGATCTTTGGTT
CATTCGGTACACCATCGTAGATAAATATATCCATAAACATCGGGCTTTTTCTTCCCTTAGCATCTGTTAT
TTGAGTGCGACAATCGAAAATTTTTGCCATTTCACCGGTATATTGAGCAAGTATATCTTCTGCCGTTTCC
ATATTGTAGTATTCGTGAGTTTCTTGAAACCAAACATCAACGAACCTTTGATATTCATCACGGTGCATAT
AAACATCAATATCATCATCCCAAGGGATAAAGCCTTTGTGGCGTATTGCACCGATTAATGTTCCACCACC
AAGAGAATAGTGAATTTGGTGTCGCTCACATAATGCGTGGAAATAATCTAATATATTGAGACAAACGAGT
TGTTGTTCTCTGAGCGTTAATTTTTTCA
Protein Sequence 
>gi|68249945|ref|YP_249057.1| phosphorylcholine transferase [Haemophilus influenzae 86-028NP]
MKKLTLREQQLVCLNILDYFHALCERHQIHYSLGGGTLIGAIRHKGFIPWDDDIDVYMHRDEYQRFVDVW
FQETHEYYNMETAEDILAQYTGEMAKIFDCRTQITDAKGRKSPMFMDIFIYDGVPNEPKIIYPLMKKHRR
IKLRFSSCKKRWLRSKENTLQRTILGKLSHFLFSKMQKNLAQFQIKYPIKQCDYIGLVLSDYGGWQKSYM
PKEYFNHIVYKEFEGRQFQVMNGYHEHLTQYYGDYMKLPPEEDQKPHHIQEAYIL
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: licD mutant is more rapidly cleared in mouse pulmonary infection than the wild type (Pang et al., 2008).
COG COG3475M, under M: Cell wall/membrane/envelope biogenesis
References
Pang et al., 2008: Pang B, Winn D, Johnson R, Hong W, West-Barnette S, Kock N, Swords WE. Lipooligosaccharides containing phosphorylcholine delay pulmonary clearance of nontypeable Haemophilus influenzae. Infection and immunity. 2008; 76(5); 2037-2043. [PubMed: 18347044].