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hbpA

Victor ID 2836
Gene Name hbpA
Sequence Strain (Species/Organism) Haemophilus influenzae 86-028NP
NCBI Gene ID 3430322
NCBI Protein GI 68249447
Locus Tag NTHI1021
Genbank Accession CP000057
Protein Accession YP_248559
Other Database IDs UniProtKB-ID: Q4QM48_HAEI8
UniRef100: UniRef100_Q4QM48
UniRef90: UniRef90_P33950
UniRef50: UniRef50_P33950
UniParc: UPI000053E15B
EMBL: CP000057
EMBL-CDS: AAX87899.1
RefSeq_NT: NC_007146.2
GenomeReviews: CP000057_GR
KEGG: hit:NTHI1021
eggNOG: COG0747
HOGENOM: HBG688042
OMA: RASNPNP
ProtClustDB: CLSK870165
BioCyc: HINF281310:NTHI1021-MONOMER
Taxonomy ID 281310
Gene Starting Position 965027
Gene Ending Position 966676
Gene Strand (Orientation) +
Protein Name heme-binding protein A
Protein pI 6.64
Protein Weight 57655.56
Protein Length 549
Protein Note Similar to: HI0853, HBPA_HAEIN
DNA Sequence 
>gi|162960935:965027-966676 Haemophilus influenzae 86-028NP chromosome, complete genome
TATGCTTATGAAACTAAAAGCAACATTAACTCTCGCCGCTGCAACTCTTGTTTTGGCAGCTTGTGATCAA
TCTAGCTCGGCAAATAAATCTACTGCTCAAACTGAAGCAAAATCCTCGTCAAATAATACTTTCGTTTATT
GCACAGCGAAAGCTCCATTGGGATTTAGCCCTGCGTTAATAATTGAAGGTACTTCTTATAATGCAAGCTC
ACAACAAGTGTATAACCGCTTAGTTGAATTTAAAAAAGGCTCAACGGATATTGAACCAGCTTTAGCTGAA
AGCTGGGAAATTAGCGATGATGGTTTAAGTTATACTTTTCATTTAAGAAAGGGTGTTAAATTCCATACAA
CAAAAGAATTTACCCCGACACGTGATTTTAATGCAGATGATGTTGTATTTTCATTCCAACGTCAGTTAGA
TCCAAATCATCCATATCACAATGTATCTAAGGGGACTTATCCATATTTTAAAGCAATGAAATTCCCTGAA
TTGTTGAAATCAGTGGAGAAAGTAGACGATAACACAATTCGTATTACCTTAAACAAGACAGATGCGACTT
TCTTGGCTAGTCTTGGTATGGATTTTATTTCTATTTATTCTGCAGAATATGCTGATTCAATGCTGAAAGC
GGGTAAACCAGAAACACTTGATAGTCGCCCAGTGGGGACAGGCCCTTTTGTTTTTGTGGATTATAAAACA
GATCAAGCCATACAATATGTTGCGCATGAAAATTATTGGAAAGGTAGAACACCTTTAGATCGTTTAGTCA
TTAGCATTGTGCCTGATGCAACAACACGTTATGCAAAATTACAGGCGGGTACTTGCGATTTAATTTTATT
CCCAAATGTAGCGGATTTAGCCAAAATGAAAACCGATCCAAAAGTACAACTTTTGGAACAAAAAGGTTTG
AACGTAGCGTATATCGCATTCAATACCGAAAAAGCACCGTTTGATAATGTCAAAGTGCGCCAAGCGTTGA
ATTACGCAGTGGATAAAAAAGCGATTATTGAAGCGGTTTATCAAGGCGCAGGAATATCAGCTAAAAACCC
ACTTCCTCCAACAATTTGGAGTTATAATGATGAAATCCAAGATTATCCGTACGATCCAGAAAAAGCAAAA
CAACTTTTAGCAGAAGCGGGTTATCCAAATGGTTTTGAAACTGATTTCTGGATTCAACCTATTATTCGTG
CTTCTAATCCAAATCCAAAACGTATGGCTGAATTAATTATGGCGGATTGGGCGAAAATTGGTGTAAAAAC
TAACCCAGTGACTTATGAATGGGCTGATTATAGAAAACGAGCAAAAGAGGGAGAATTAACTGCGGGTATC
TTTGGTTGGTCTGGCGACAATGGCGATCCTGATAATTTCTTATCCCCATTATTAGGTAGCTCAAATATAG
GTAATTCTAATATGGCACGTTTCAATAATTCAGAATTTGATGCTTTACTCAATGAGGCTATTGGATTAAC
CAATAAGGAAGAACGTGCGAAACTTTATAAACAAGCTCAAGTTATTGTCCATAATCAAGCACCTTGGATT
CCAGTTGCCCACTCTGTTGGTTTTGCGCCACTTAGTCCTCGTGTAAAAGGTTATGTACAAAGCCCATTTG
GCTATGACGCTTTTTATGGTGTGAGTGTTGATGGTAAATA
Protein Sequence 
>gi|68249447|ref|YP_248559.1| heme-binding protein A [Haemophilus influenzae 86-028NP]
MLMKLKATLTLAAATLVLAACDQSSSANKSTAQTEAKSSSNNTFVYCTAKAPLGFSPALIIEGTSYNASS
QQVYNRLVEFKKGSTDIEPALAESWEISDDGLSYTFHLRKGVKFHTTKEFTPTRDFNADDVVFSFQRQLD
PNHPYHNVSKGTYPYFKAMKFPELLKSVEKVDDNTIRITLNKTDATFLASLGMDFISIYSAEYADSMLKA
GKPETLDSRPVGTGPFVFVDYKTDQAIQYVAHENYWKGRTPLDRLVISIVPDATTRYAKLQAGTCDLILF
PNVADLAKMKTDPKVQLLEQKGLNVAYIAFNTEKAPFDNVKVRQALNYAVDKKAIIEAVYQGAGISAKNP
LPPTIWSYNDEIQDYPYDPEKAKQLLAEAGYPNGFETDFWIQPIIRASNPNPKRMAELIMADWAKIGVKT
NPVTYEWADYRKRAKEGELTAGIFGWSGDNGDPDNFLSPLLGSSNIGNSNMARFNNSEFDALLNEAIGLT
NKEERAKLYKQAQVIVHNQAPWIPVAHSVGFAPLSPRVKGYVQSPFGYDAFYGVSVDGK
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: hbpA mutant is attenuated in mice (Rosadini et al., 2008).
COG COG0747E, under E: Amino acid transport and metabolism
References
Rosadini et al., 2008: Rosadini CV, Wong SM, Akerley BJ. The periplasmic disulfide oxidoreductase DsbA contributes to Haemophilus influenzae pathogenesis. Infection and immunity. 2008; 76(4); 1498-1508. [PubMed: 18212083].