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CTC01888

Victor ID 2826
Gene Name CTC01888
Sequence Strain (Species/Organism) Clostridium tetani E88
NCBI Gene ID 1060232
NCBI Protein GI 28211522
Locus Tag CTC01888
Genbank Accession AE015927
Protein Accession NP_782466
Other Database IDs UniProtKB-ID: Q893D9_CLOTE
UniRef100: UniRef100_Q893D9
UniRef90: UniRef90_Q893D9
UniRef50: UniRef50_Q0TUS0
UniParc: UPI00000104EA
EMBL: AE015927
EMBL-CDS: AAO36403.1
RefSeq_NT: NC_004557.1
HSSP: P19995
GenomeReviews: AE015927_GR
KEGG: ctc:CTC01888
NMPDR: fig|212717.1.peg.1688
HOGENOM: HBG337470
OMA: GAYVAQF
ProtClustDB: CLSK877006
BioCyc: CTET212717:CTC_01888-MONOMER
Taxonomy ID 212717
Gene Starting Position 2007253
Gene Ending Position 2008836
Gene Strand (Orientation) -
Protein Name tetanolysin O
Protein pI 7.52
Protein Weight 55603.48
Protein Length 527
DNA Sequence 
>gi|28209834:2007253-2008836 Clostridium tetani E88 chromosome, complete genome
TTTACATTTTAGTTTCAATTGATGTCTTTGGATATAATGTTGTACCCCATATATAGAAAGTTCTTTCTTT
TGCTAGTGGTATATTTTTAACATCTACAATGGTTCTCCACCATTCCCATGCAAGACCTGTACATTCTCTT
ATTTTTACAGATATATTTCGTGCATTTCCTTTTAAATATATTTCTGTATTAAAATGAGCCGTTCTATCTC
TATTATTTCCTTCCCAAGCTTTATGTTCAACTATTTCATTTCCCTTTTCGTCATAGCTAACCTCATCCCA
TGTTACTTGGAATTGAGCAACATACGCTCCACTATGATCAAGTACTATTTTACCATTAGTATATTCTGTT
GCAGTTGTTTCTATATATTCTGTTTTATTATTTACGGATGCTATACTATTGTCTTTTAAAAATGTAGTAG
TATATGAAATTGGATATCCTGGATTTTGTGGACTATACACTGAATTATTTTTAATAATATTTCTTATTTC
ATCAAAATCCTTAGTGATTATCTTATTATGTTCTTGTGCTCCTCCCCCTAAAACAGTAGCTGTAAATGAA
CTTTGATTTAATATATCCTTATATTCTGCATTACTACTTATATCCTGGTTATTGATTAGTGCTTTAAAAG
CTGCTTTAACATGTGAACTCTTAGAGGTAGTTTCAAGTTTTACATAAATTGTTCTACCATATGCAACATT
TGAAACATATGCAGGAGGATTATTATTATTTATCCCCTTTAAAGCCAATTCATCAAAAGTTACACTATCA
CCAAATAAATCTGATGGACGATTTGGTGGGTCTACACTTACTGTATAAAAAATTTGTTTGTATGCAAGAA
GCATAACCTTTTTTTCACCTTTAAATATGGAATCAAAATCTATATTTAATGCTTTGTTTAAAGCTTTAAA
ATTGCATCCAACTGCTGCAGATAACTGTGATTGGCTATACACCATAGTATCAGAATAACTCATTCTTGTA
GGTATAGTATATTTAGATGAATACTTTGAATTCCATGTATCTAATATAGAATTTATTGCAGAATTAACTG
AGGAGTAGGTAGGTGAATTAACAACTTTCTTACCATCTTCAGCCATACCCGGTAAGTCAACACTTATAGT
AATAGGTTTTCTCTCACATGAAATTATATCAGGTTTGTTTTCCATAAGATTTCTGTTAGCAAGTTGTATA
GCTCCAGGATAAGTTCTATCATTTATTGAGTCTATAATTGAAATGTCTGCTGTGGAATCTGAAATACTCT
TCTTCTCACGTTTTACCACAATGAACTTATCTGGATTTTCAAATCCTTCAGCAGGTACAAAATTTTCTAC
CTGTTCACCATTATATGATAATATCTTACGTGGATCATAGGATAATCCATAAATATTTTTGTCTATGTCA
CTACTGTTGTCTTTTGCCAAATTACATTTTGTATTTGACGTTACTACTTGTCCATTATTGATTAATGAAT
GTTCCTCTACATTTCCTTTAGCTAATACATTACTGGAATTATAATTAGATATTAAGCCAGTCATTGAAAA
TATTAGCAATGAACGTGATACAAATTTTAATACATTTTTGTTCA
Protein Sequence 
>gi|28211522|ref|NP_782466.1| tetanolysin O [Clostridium tetani E88]
MNKNVLKFVSRSLLIFSMTGLISNYNSSNVLAKGNVEEHSLINNGQVVTSNTKCNLAKDNSSDIDKNIYG
LSYDPRKILSYNGEQVENFVPAEGFENPDKFIVVKREKKSISDSTADISIIDSINDRTYPGAIQLANRNL
MENKPDIISCERKPITISVDLPGMAEDGKKVVNSPTYSSVNSAINSILDTWNSKYSSKYTIPTRMSYSDT
MVYSQSQLSAAVGCNFKALNKALNIDFDSIFKGEKKVMLLAYKQIFYTVSVDPPNRPSDLFGDSVTFDEL
ALKGINNNNPPAYVSNVAYGRTIYVKLETTSKSSHVKAAFKALINNQDISSNAEYKDILNQSSFTATVLG
GGAQEHNKIITKDFDEIRNIIKNNSVYSPQNPGYPISYTTTFLKDNSIASVNNKTEYIETTATEYTNGKI
VLDHSGAYVAQFQVTWDEVSYDEKGNEIVEHKAWEGNNRDRTAHFNTEIYLKGNARNISVKIRECTGLAW
EWWRTIVDVKNIPLAKERTFYIWGTTLYPKTSIETKM
Molecule Role Virulence factor
Molecule Role Annotation TOXIN: tetanolysin O is a cytolysin that catalyses the lysis of cholesterol-containing membranes (Brüggemann and Gottschalk, 2004).
References
Brüggemann and Gottschalk, 2004: Brüggemann H, Gottschalk G. Insights in metabolism and toxin production from the complete genome sequence of Clostridium tetani. Anaerobe. 2004; 10(2); 53-68. [PubMed: 16701501].