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STM4260

Victor ID 2815
Gene Name STM4260
Sequence Strain (Species/Organism) Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
NCBI Gene ID 1255786
NCBI Protein GI 16767510
Locus Tag STM4260
Protein Accession NP_463125.1
Other Database IDs UniProtKB-ID: O85314_SALTY
UniRef100: UniRef100_D0ZRX6
UniRef90: UniRef90_D0ZRX6
UniRef50: UniRef50_D0ZRX6
UniParc: UPI00000D014D
EMBL: AF060869
EMBL: AE006468
EMBL: AJ576316
EMBL-CDS: AAC26642.1
EMBL-CDS: AAL23084.1
EMBL-CDS: CAE11796.1
RefSeq_NT: NC_003197.1
GenomeReviews: AE006468_GR
KEGG: stm:STM4260
HOGENOM: HBG391186
OMA: ARLEYKS
ProtClustDB: CLSK894544
BioCyc: STYP99287:STM4260-MONOMER
Taxonomy ID 99287
Gene Starting Position 4481179
Gene Ending Position 4482456
Gene Strand (Orientation) +
Protein Name predicted cation efflux pump
DNA Sequence 
>gi|16763390:4481179-4482456 Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 chromosome, complete genome
AATGAATAGAAGACAAAGCGATCATCTCATGATGATAATTATTTCTTTGACGATCTTAATTATTATCCTT
ACCTACTTTATAGAAATTAATTCAGTGGTTCATGGTCAGGGCGTTATCACTACTAAAGATAATGCTCAGT
TAATATCTCTTTCTAAAGGAGGGACGATACAAGATATTTATGTAGCCGAGGGTGATACTGTAAAAAAAGG
AGAACTCCTTGCAAAGGTCGTTAACCTTGATCTGCAAAAAGAATATCAAAGGTATAGAACTCAAAAAGGG
TATCTGGATAAAGATGTTAACGAAATATCTTTCATTCTTGATAAAGAAAATGAGAGTGGGTTGATTACCC
TGGATGGCACCCGTTCTTTAAGCAATAAAGAGGTAAAAGCGAATATTGAATTAGTGCATAGTCAGATAAG
AGCTAAAGAGTTAAAAAAAACCTCTCTTGATTCTGAGATTAGCGGATTACAAGAGAAGCTGAGTTCGAAA
GAAAAAGAACTCGCATTGCTTGCCGAAGAAATAAATATTCTTTCCCCACTGGTAAAAAAAGGAATTAGCC
CATATACCAATTTTCTTAACAAGAAACAGGCGTATATAAAAGTTAAGTCTGAAATTAATGATATTGAAAG
TAGCATCACTTTAAAAAAAGATGATATTGAGTTGGTTGTTAATGATATTGAGGCGCTTAATAATGAATTG
CGACTATCTTTATCTAAAATAATATCTAAAAATCTTCAGGAACTTGAGGTTGTTAACTCTACATTAAAAG
TAATAGAGAAGCAGATAAATGAGGAGGATATCTATTCACCGGTTGACGGTGTAATTTATAAAATCAATAA
AAGTGCCACTACTCATGGTGGTGTGATTCAGGCGGCGGACTTACTTTTTGAAATAAAACCAAAAGTAAGG
ACTATGCTGGCCGATGTGAAAATATTACCCAAATACCGTGACCAAATATATGTAGATGAAGCCGTTAAAC
TGGATGTGCAGTCAATTATCCAACCAAAGATAAAATCGTATAATGCGACTATCGATAATATTAGCCCTGA
TTCCTATGAGGAAAATACCGGAGGAACAATTCAGCGTTATTATAAAGTAATTATTGCATTCGATGTTAAT
GAAGATGATTTACGGTGGTTAAAACCAGGTATGACTGTTGACGCCAGTGTAATTACCGGAAAACACAGCA
TTATGGAATACCTGTTATCTCCCTTGATGAAAGGCGTGGACAAAGCCTTTTCAGAACCAGTTAATACTAA
ACGATTAGATACACCTTG
Protein Sequence 
>gi|16767510|ref|NP_463125.1| membrane permease [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] MNRRQSDHLMMIIISLTILIIILTYFIEINSVVHGQGVITTKDNAQLISLSKGGTIQDIYVAEGDTVKKGELLAKVVNLDLQKEYQRYRTQKGYLDKDVNEISFILDKENESGLITLDGTRSLSNKEVKANIELVHSQIRAKELKKTSLDSEISGLQEKLSSKEKELALLAEEINILSPLVKKGISPYTNFLNKKQAYIKVKSEINDIESSITLKKDDIELVVNDIEALNNELRLSLSKIISKNLQELEVVNSTLKVIEKQINEEDIYSPVDGVIYKINKSATTHGGVIQAADLLFEIKPKVRTMLADVKILPKYRDQIYVDEAVKLDVQSIIQPKIKSYNATIDNISPDSYEENTGGTIQRYYKVIIAFDVNEDDLRWLKPGMTVDASVITGKHSIMEYLLSPLMKGVDKAFSEPVNTKRLDTP
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: STM4260 mutant is attenuated in mice (Lawley et al., 2006).
COG COG0845M, under M: Cell wall/membrane/envelope biogenesis
References
Lawley et al., 2006: Lawley TD, Chan K, Thompson LJ, Kim CC, Govoni GR, Monack DM. Genome-wide screen for Salmonella genes required for long-term systemic infection of the mouse. PLoS pathogens. 2006; 2(2); e11. [PubMed: 16518469].