Search: for Help
About
Introduction
Statistics
Your PHIDIAS
Register or Login
Philert
Submission
Curated Data
Victors
BBP (Brucella)
Phinfo
Phinet
HazARD
Data Analysis
Phigen
Pacodom
BLAST
Help & Documents
Documents
FAQs
Links
Acknowledgements
Disclaimer
Contact Us
UMMS Logo

trxA

Victor ID 2800
Gene Name trxA
Sequence Strain (Species/Organism) Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
NCBI Gene ID 1255441
NCBI Protein GI 16767191
Locus Tag STM3915
Protein Accession NP_462806.1
Other Database IDs UniProtKB-ID: THIO_SALTY
UniRef100: UniRef100_P0AA27
UniRef90: UniRef90_P0AA27
UniRef50: UniRef50_P0AA27
UniParc: UPI000003112A
EMBL: D10015
EMBL: Z21789
EMBL: AF233324
EMBL: AE006468
EMBL-CDS: BAA00903.1
EMBL-CDS: CAA79851.1
EMBL-CDS: AAF33471.1
EMBL-CDS: AAL22765.1
RefSeq_NT: NC_003197.1
GenomeReviews: AE006468_GR
KEGG: stm:STM3915
HOGENOM: HBG493509
OMA: TLMLFKG
ProtClustDB: PRK09381
BioCyc: STYP99287:STM3915-MONOMER
Taxonomy ID 99287
Gene Starting Position 4124835
Gene Ending Position 4125164
Gene Strand (Orientation) +
Protein Name thioredoxin
DNA Sequence 
>gi|16763390:4124835-4125164 Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 chromosome, complete genome
TATGAGCGATAAAATTATTCACCTGACTGACGACAGTTTTGACACGGATGTACTCAAAGCGGACGGGGCT
ATCCTCGTTGATTTCTGGGCAGAGTGGTGCGGGCCGTGTAAAATGATCGCTCCGATTCTGGATGAAATCG
CTGACGAATATCAGGGCAAATTGACCGTTGCCAAACTGAACATTGACCAGAACCCAGGTACTGCGCCTAA
ATATGGCATCCGCGGTATTCCGACTCTGCTGCTGTTTAAAAACGGCGAAGTGGCGGCAACCAAAGTAGGC
GCACTGTCTAAAGGTCAGTTGAAAGAGTTTCTCGACGCCAATCTGGCGTA
Protein Sequence 
>gi|16767191|ref|NP_462806.1| thioredoxin [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] MSDKIIHLTDDSFDTDVLKADGAILVDFWAEWCGPCKMIAPILDEIADEYQGKLTVAKLNIDQNPGTAPKYGIRGIPTLLLFKNGEVAATKVGALSKGQLKEFLDANLA
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: trxA mutant is attenuated in mice (Peters et al., 2010).
COG COG3118O, under O: Posttranslational modification, protein turnover, chaperones
References
Peters et al., 2010: Peters SE, Paterson GK, Bandularatne ES, Northen HC, Pleasance S, Willers C, Wang J, Foote AK, Constantino-Casas F, Scase TJ, Blacklaws BA, Bryant CE, Mastroeni P, Charles IG, Maskell DJ. Salmonella enterica serovar typhimurium trxA mutants are protective against virulent challenge and induce less inflammation than the live-attenuated vaccine strain SL3261. Infection and immunity. 2010; 78(1); 326-336. [PubMed: 19884329].