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misL from Salmonella enterica subsp. enterica serovar Typhimurium str. LT2

Victor ID 2793
Gene Name misL from Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
Sequence Strain (Species/Organism) Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
NCBI Gene ID 1255281
NCBI Protein GI 16767041
Locus Tag STM3757
Protein Accession NP_462656.1
Other Database IDs UniProtKB-ID: Q9Z625_SALTY
UniRef100: UniRef100_Q9Z625
UniRef90: UniRef90_B4U012
UniRef50: UniRef50_B4U012
UniParc: UPI00000D015D
EMBL: AF106566
EMBL: AE006468
EMBL-CDS: AAD16954.1
EMBL-CDS: AAL22615.1
RefSeq_NT: NC_003197.1
TCDB: 1.B.12.1.3
GenomeReviews: AE006468_GR
KEGG: stm:STM3757
NMPDR: fig|99287.1.peg.3632
HOGENOM: HBG468348
OMA: GAYDYNV
ProtClustDB: CLSK894828
BioCyc: STYP99287:STM3757-MONOMER
Taxonomy ID 99287
Gene Starting Position 3954760
Gene Ending Position 3957627
Gene Strand (Orientation) +
Protein Name putative autotransporter
DNA Sequence 
>gi|16763390:3954760-3957627 Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 chromosome, complete genome
AATGCCAACTCCCCAAAATTACTCATTCATCGCCATAGCGGTATCAGCAGCATTAGCCTCTATGGTATTT
CCCTCCCAGGCGGCCTGGGTTGACGTTGATAGTCTGCCATCCAGTGGGCTGGTCAGTCAGTTGCCGCCGG
AATTACAGGCTATTATTCCCGCTCAGGCCAGTACCGGTTTCACCAAAGTCGGGACCATGCCCAACTACGT
TTATCAGTGGAACACCGGCACCATCCCGGTTTATGGCAATGGCCTCACGCTTAATGGGCCGGGCGCGGAG
GCGTTTGAACACACTGTCACGGTTATTCAAAACAGCGGGACGGGAAGTCCGGGCGTGATTTTTGGCAACG
ACCTGACCATTCGGACGCAGTCGGCGAATGCCGCGAATAATGGTAGAGACGTCGATGGCATCCGTACTCA
CGGCGCGAATACTCCGGATAACCCGGTATTTATTATTACCGGTGACCGTACCCGCATCTACGTGGATGGT
CAGGATGGTGACGGTATTAACGCCGGATATAACTCACTGGGCCAGGGTTGGACCGGATCGGCCAATATTT
ACGTCGGCGACGATCTGTATATCAAAACGACCGGTAGCCAGGGACGTGGCATTACAGCCAACGCCATGCG
GGATGCGTCACGTGCCAAAAATACGATTGTCGTCGGCAATCGTGCGCATATTGTTACTACCGGCGACAGT
TCGGAGGGGCTGCGTACCGGACAAAGCGGTTCGTTGATTCGTCTGGGTGACGATGCAACTATCGAAACAT
CCGGCGCATCCTCAACGGGGATTTACGCAGCATCCTCCTCCAGAACCGAGCTTGGCAACAACGCTACTAT
TACGGTGAACGGTGCCAGCGCACACGCGGTATATGCAACTAACGCTACCGTTAATTTGGGAGAGAATGCC
ACTATTAGCGTTAACAGCGCCAGTAAGGCTGCATCCTATAGTAAAGCCCCTGCCGGTTTATACGCCCTCT
CCCGAGGCGCCATTAATCTGGCAGGCGGTGCGGCTATTACTATGGCGGGCGATAACAGTAGCGAAAGTTA
CGCCATCAGCACGGAGACTGGCGGCATTGTTGACGGTTCTTCAGGAGGTCGTTTCGTCATCGACGGTGAT
ATTCGTGCTGCTGGCGCCACCGCTGCCAGCGGTACGCTACCGCAGCAGAACAGTACGATTAAGCTCAATA
TGACGGACAACTCGCGATGGGACGGGGCGTCGTACATCACCAGCGCTACGGCGGGCACAGGCGTTATCTC
TGTACAAATGAGCGATGCGACCTGGAATATGACCAGCAGCTCAACGCTCACTGACCTGACGCTGAATAGT
GGCGCAACCATTAACTTCAGCCATGAAGATGGCGAACCATGGCAAACGCTCACCATCAATGAAGATTATG
TAGGCAACGGCGGTAAGCTGGTCTTTAATACTGTGCTCAACGATGATGATTCCGAAACGGACAGGCTGCA
GGTTCTCGGCAATACTTCAGGCAACACATTTGTTGCAGTAAATAATATTGGAGGAGCCGGGGCGCAAACC
ATTGAAGGTATTGAAATTGTTAACGTTGCTGGCAATTCCAACGGTACTTTCGAAAAAGCAAGCCGTATTG
TTGCCGGAGCCTATGACTACAACGTGGTGCAGAAAGGTAAAAACTGGTATCTGACCAGCTACATTGAGCC
GGACGAACCGATTATTCCTGATCCAGTAGACCCTGTTATCCCTGACCCTGTCGTTCCCGATCCGGTGGAC
CCTGATCCAGTAGACCCGGTTATCCCTGACCCTGTGATTCCCGATCCGGTGGACCCTGATCCAGTAGACC
CTGAGCCAGTAGACCCGGTCATCCCTGATCCGACAATTCCTGACATAGGGCAATCTGACACACCGCCGAT
AACAGAACATCAGTTCCGTCCGGAAGTGGGCAGCTATCTTGCCAACAACTATGCGGCAAATACGCTGTTC
ATGACGCGTCTCCATGACCGTCTGGGTGAAACCCAGTACACCGACATGCTGACGGGTGAGAAGAAGGTCA
CCAGCCTGTGGATGCGTAACGTCGGCGCCCATACTCGCTTCAACGATGGCAGCGGGCAGCTAAAAACCCG
CATCAACAGCTATGTGTTACAACTGGGAGGCGATCTGGCACAGTGGAGCACTGACGGTCTTGACCGTTGG
CATATTGGTGCAATGGCAGGTTATGCCAACAGCCAGAACCGCACGCTGTCGTCCGTGAGTGACTATCATT
CCCGTGGTCAAGTCACCGGTTACAGCGTCGGCCTTTACGGCACCTGGTATGCTAACAATATCGATCGGTC
TGGGGCTTATGTGGATACCTGGATGCTGTACAACTGGTTTGATAACAAGGTCATGGGTCAGGATCAGGCC
GCTGAGAAATATAAATCCAAAGGAATTACCGCCTCGGTTGAAGCCGGTTACAGCTTCAGGTTAGGTGAAA
GCGCGCATCAAAGCTACTGGTTGCAGCCCAAAGCGCAGGTGGTATGGATGGGCGTGCAGGCTGACGACAA
TCGCGAAGCCAATGGTACCCTCGTCAAGGATGATACCGCCGGTAATCTGCTAACCCGCATGGGCGTAAAA
GCCTATATTAACGGCCACAATGCTATTGATAACGATAAATCTCGAGAGTTCCAGCCATTCGTGGAAGCGA
ACTGGATCCATAATACGCAGCCTGCCAGCGTGAAGATGGACGATGTCAGCAGCGATATGCGTGGTACGAA
GAATATTGGAGAACTGAAAGTGGGTATTGAAGGACAAGTTACCCCGCGCCTGAACGTATGGGGTAACGTG
GCGCAACAGGTGGGTGACACAGGTTATAGTGATACCCAAGGAATGCTGGGGATGAAATACAGTTTCTG
Protein Sequence 
>gi|16767041|ref|NP_462656.1| autotransported protein [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] MPTPQNYSFIAIAVSAALASMVFPSQAAWVDVDSLPSSGLVSQLPPELQAIIPAQASTGFTKVGTMPNYVYQWNTGTIPVYGNGLTLNGPGAEAFEHTVTVIQNSGTGSPGVIFGNDLTIRTQSANAANNGRDVDGIRTHGANTPDNPVFIITGDRTRIYVDGQDGDGINAGYNSLGQGWTGSANIYVGDDLYIKTTGSQGRGITANAMRDASRAKNTIVVGNRAHIVTTGDSSEGLRTGQSGSLIRLGDDATIETSGASSTGIYAASSSRTELGNNATITVNGASAHAVYATNATVNLGENATISVNSASKAASYSKAPAGLYALSRGAINLAGGAAITMAGDNSSESYAISTETGGIVDGSSGGRFVIDGDIRAAGATAASGTLPQQNSTIKLNMTDNSRWDGASYITSATAGTGVISVQMSDATWNMTSSSTLTDLTLNSGATINFSHEDGEPWQTLTINEDYVGNGGKLVFNTVLNDDDSETDRLQVLGNTSGNTFVAVNNIGGAGAQTIEGIEIVNVAGNSNGTFEKASRIVAGAYDYNVVQKGKNWYLTSYIEPDEPIIPDPVDPVIPDPVVPDPVDPDPVDPVIPDPVIPDPVDPDPVDPEPVDPVIPDPTIPDIGQSDTPPITEHQFRPEVGSYLANNYAANTLFMTRLHDRLGETQYTDMLTGEKKVTSLWMRNVGAHTRFNDGSGQLKTRINSYVLQLGGDLAQWSTDGLDRWHIGAMAGYANSQNRTLSSVSDYHSRGQVTGYSVGLYGTWYANNIDRSGAYVDTWMLYNWFDNKVMGQDQAAEKYKSKGITASVEAGYSFRLGESAHQSYWLQPKAQVVWMGVQADDNREANGTLVKDDTAGNLLTRMGVKAYINGHNAIDNDKSREFQPFVEANWIHNTQPASVKMDDVSSDMRGTKNIGELKVGIEGQVTPRLNVWGNVAQQVGDTGYSDTQGMLGMKYSF
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: misL mutant is attenuated in mice (Dorsey et al., 2005).
COG COG3468MU, under M: Cell wall/membrane/envelope biogenesis; U: Intracellular trafficking, secretion, and vesicular transport
References
Dorsey et al., 2005: Dorsey CW, Laarakker MC, Humphries AD, Weening EH, Bäumler AJ. Salmonella enterica serotype Typhimurium MisL is an intestinal colonization factor that binds fibronectin. Molecular microbiology. 2005; 57(1); 196-211. [PubMed: 15948960].