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envZ

Victor ID 2782
Gene Name envZ
Sequence Strain (Species/Organism) Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
NCBI Gene ID 1255024
NCBI Protein GI 16766789
Locus Tag STM3501
Protein Accession NP_462404.1
Other Database IDs UniProtKB-ID: ENVZ_SALTY
UniRef100: UniRef100_P08982
UniRef90: UniRef90_P0AEJ4
UniRef50: UniRef50_P0AEJ4
UniParc: UPI0000129FE2
EMBL: X12374
EMBL: AE006468
EMBL-CDS: CAA30935.1
EMBL-CDS: AAL22363.1
RefSeq_NT: NC_003197.1
GenomeReviews: AE006468_GR
KEGG: stm:STM3501
HOGENOM: HBG334875
OMA: KPSYQQI
ProtClustDB: PRK09467
BioCyc: STYP99287:STM3501-MONOMER
Taxonomy ID 99287
Gene Starting Position 3658256
Gene Ending Position 3659608
Gene Strand (Orientation) -
Protein Name osmolarity sensor protein
DNA Sequence 
>gi|16763390:3658256-3659608 Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 chromosome, complete genome
CTTATGCCTCTTTTGTCGTCCCCTGGACGCGAGCCACAGGAACCGGTAGCCAGGCGCGAATCGACAATCC
GCCACGCTCGCTGGTGCCAATCTCCAGCATCCCGTTATGGTTATCGATAATGCGCTGCACAATCGCCAGC
CCCAGCCCTGTGCCGCTGGTGCTACGGGCGCTGTCGCCACGCACAAAAGGCTGGAACAGATGTTTACGCT
GCTCCGGCTTAATGCCCGGCCCGTCATCTTCTACCTGAAACCAGGCGCGATGCGACTCGGTGCCGCTGCT
GACCTTAATCCAGCCGTTGCCATAGCGGGCAGCATTGACCACCATATTCGCCACCGCGCGCTTAATCGAG
AGCGGGTGCATTTTCACCTGGATGCTGCCTGCCTGAAGCGCAGTGTTAATCTCACGCTCATAGCCGCTTT
CCGCCGCAATCACCTCGCCCAGCACGGAATTGAGATCCGCCATCTCCATTGGCATTTCCTGACCGGTACG
CAGATAGTCAATAAACTGTTCGATAATGGCGTTACACTCTTCGATGTCTTTATTGATCGACTCCGCGAGA
TAACCGTCTTCCTCGCCCATCATCTCCGTCGCCAGACGAATACGGGTCAACGGCGTGCGCAAGTCGTGGC
TGACGCCCGCCATCAATAGCGTACGGTCATCGGCCAATTGCTTCACGCCGGCTGCCATATGGTTAAACGC
CCGGGTCACAGAGCGCACTTCAGAGGCGCCATATTCACGCAGCGGCGGCGGAATAATTCCCTTCCCTACC
TGCAAGGCGGCATGTTCAAGATCCACTAACGGTCGATTCTGTATACGAATAAACAGCCACGCGCCGCCTA
TCGCCAGGAGCATGATCGCCAGCGTGTAACGGAAAAGCGGAGAAAAATCGCCCTGATGAATCTCGGTCAG
CGGCACGCGCACCCAGATATTGGGCGACAGCCAGGTTTTGAGCCACACGACGGGCGAGCTTTTGTTGACC
TCAACGCGCACTTCCGTCGGGCCGCCTAATTGCTGCGCCATCTGGTGGCTTAAGAATTCGTAGTGTTGCG
CCCAACGCAACCCGGCCTCTTCGGCGGCTTCGTTGGTGTAGAGAGAGATCCCCAGCTCGCGATAGATTTC
CCGGCGAAACGCAGGCGGCACGACTAACTGCGTGCCGTCCTCCAGTTGCAGCTTATCGGTCATCAGCATA
CGGACTTCGTAAGCCAGAACCTTATTAAACTGCTGGAGGCTCGGCAAAATCGCGAAGTTCAGCACCACCA
GGTAGGTCGTCACCAGGCTGACGAACAGCAAGGTGACGATGAGCAACAGCGTGCGGGCAAATGAACTTCG
CGGTGAGAAGCGCATTCGCCTCA
Protein Sequence 
>gi|16766789|ref|NP_462404.1| osmolarity sensor protein EnvZ [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] MRRMRFSPRSSFARTLLLIVTLLFVSLVTTYLVVLNFAILPSLQQFNKVLAYEVRMLMTDKLQLEDGTQLVVPPAFRREIYRELGISLYTNEAAEEAGLRWAQHYEFLSHQMAQQLGGPTEVRVEVNKSSPVVWLKTWLSPNIWVRVPLTEIHQGDFSPLFRYTLAIMLLAIGGAWLFIRIQNRPLVDLEHAALQVGKGIIPPPLREYGASEVRSVTRAFNHMAAGVKQLADDRTLLMAGVSHDLRTPLTRIRLATEMMGEEDGYLAESINKDIEECNAIIEQFIDYLRTGQEMPMEMADLNSVLGEVIAAESGYEREINTALQAGSIQVKMHPLSIKRAVANMVVNAARYGNGWIKVSSGTESHRAWFQVEDDGPGIKPEQRKHLFQPFVRGDSARSTSGTGLGLAIVQRIIDNHNGMLEIGTSERGGLSIRAWLPVPVARVQGTTKEA
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: envZ mutant is attenuated in mice (Hensel et al., 1995).
COG COG0642T, under T: Signal transduction mechanisms
References
Hensel et al., 1995: Hensel M, Shea JE, Gleeson C, Jones MD, Dalton E, Holden DW. Simultaneous identification of bacterial virulence genes by negative selection. Science (New York, N.Y.). 1995; 269(5222); 400-403. [PubMed: 7618105].