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fkpA

Victor ID 2778
Gene Name fkpA
Sequence Strain (Species/Organism) Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
NCBI Gene ID 1254976
NCBI Protein GI 16766742
Locus Tag STM3453
Protein Accession NP_462357.1
Other Database IDs UniProtKB-ID: Q8ZLL6_SALTY
UniRef100: UniRef100_A9MT12
UniRef90: UniRef90_P45523
UniRef50: UniRef50_P45523
UniParc: UPI00000D75C1
EMBL: AE006468
EMBL-CDS: AAL22316.1
RefSeq_NT: NC_003197.1
HSSP: P45523
GenomeReviews: AE006468_GR
KEGG: stm:STM3453
HOGENOM: HBG731200
OMA: AYGDRDT
ProtClustDB: PRK10902
BioCyc: STYP99287:STM3453-MONOMER
Taxonomy ID 99287
Gene Starting Position 3604870
Gene Ending Position 3605688
Gene Strand (Orientation) -
Protein Name FKBP-type peptidyl-prolyl cis-trans isomerase (rotamase)
DNA Sequence 
>gi|16763390:3604870-3605688 Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 chromosome, complete genome
TTTATTTTTTAGCAGCATCTGCGGCTTTAGCGTCAGCCGCATCGGCAGGTTTAGCATCCGCTTTCGGCGC
TGGTTTGATATCCAGCAGCTCTACGTCGAATACCAGGGTTGAGTTTGCCGGGATCCCCGGAACGCCCGTT
TTACCGTAGGCCAGCTCAGGTGGGATAACCAGCTTGATCTTGCCGCCTTTCTTAATATTTTTCAGACCTT
CAGTCCAGCCAGGGATAACGCCGTCCAGACGGAAGGAGAGCGGTTCGCCGCGCGTGTAAGAGTTATCAAA
CTCTTTACCGTCGATCAGAGTACCTTTGTAGTTCACCACAACGGTATCGCTATCTTTCGGCGCCTCGCCT
GTGCCTTCTTTCTCTACTTTGTAAAGCAGGCCGGTAGAGGAGGTTTTCACACCTTTCTCTTTAGCAAAAG
CGTCGCGGAACGTTTTACCTTTTGCTTCGTTATCGGCAGCGTCTTTTTCCATCTTCGCCTGAGCAGCGCT
CTTCACGCGTGCTTCAAACGTCTGCAGCGTTTGCTCAATTTCCTGATCGGACAGTTTGCTCTTATCGGCA
AAGGCATCCTGAACGCCGGCAATCAACTGATCTTTATCCAGTTTGATGCCTAACTTTTCCTGCTCTTTAA
GCGAATTTTCCATGTAACGACCCAGCGAGGCGCCCAGCGCATAAGCCGCTTTTTGATCGTCGTTTTTAAA
TGCTGCTTTGCTATCAGCGGTAGCTGCCGGTTTCGCCGCATCAGCAGCAAAAGTGATCGGTGCGTGCATA
GCAACGGCCATCGTAGTTGCCAGCAGCGTGGCTTTAAACAGTGATTTCA
Protein Sequence 
>gi|16766742|ref|NP_462357.1| FKBP-type peptidyl-prolyl cis-trans isomerase [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] MKSLFKATLLATTMAVAMHAPITFAADAAKPAATADSKAAFKNDDQKAAYALGASLGRYMENSLKEQEKLGIKLDKDQLIAGVQDAFADKSKLSDQEIEQTLQTFEARVKSAAQAKMEKDAADNEAKGKTFRDAFAKEKGVKTSSTGLLYKVEKEGTGEAPKDSDTVVVNYKGTLIDGKEFDNSYTRGEPLSFRLDGVIPGWTEGLKNIKKGGKIKLVIPPELAYGKTGVPGIPANSTLVFDVELLDIKPAPKADAKPADAADAKAADAAKK
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: fkpA mutant exhibited a reduced ability to survive intracellularly in J774.A1 cells (Horne et al., 1997).
COG COG0545O, under O: Posttranslational modification, protein turnover, chaperones
References
Horne et al., 1997: Horne SM, Kottom TJ, Nolan LK, Young KD. Decreased intracellular survival of an fkpA mutant of Salmonella typhimurium Copenhagen. Infection and immunity. 1997; 65(2); 806-810. [PubMed: 9009347].