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tdcA from Salmonella enterica subsp. enterica serovar Typhimurium str. LT2

Victor ID 2776
Gene Name tdcA from Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
Sequence Strain (Species/Organism) Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
NCBI Gene ID 1254768
NCBI Protein GI 16766544
Locus Tag STM3245
Protein Accession NP_462159.1
Other Database IDs UniProtKB-ID: Q8ZLW0_SALTY
UniRef100: UniRef100_C0PZ18
UniRef90: UniRef90_B4T6B4
UniRef50: UniRef50_P0ACQ8
UniParc: UPI00000CD3DF
EMBL: AE006468
EMBL-CDS: AAL22118.1
RefSeq_NT: NC_003197.1
GenomeReviews: AE006468_GR
KEGG: stm:STM3245
HOGENOM: HBG417057
OMA: DEMKLQD
ProtClustDB: PRK10341
BioCyc: STYP99287:STM3245-MONOMER
Taxonomy ID 99287
Gene Starting Position 3412472
Gene Ending Position 3413410
Gene Strand (Orientation) -
Protein Name DNA-binding transcriptional activator
DNA Sequence 
>gi|16763390:3412472-3413410 Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 chromosome, complete genome
ATCATTCAATTTCTATTAACTGCCTGCGTCTGCATCCATTATATGATGAATATTGTTTAGCCAATTCTAC
TAATACTGAAGCGGCTTTTTTGATACGATAATTTTTAGACCATACCGCCGCATAACGTGCGACGGGTAAC
GTGTCTTGTATGGGTATCGTGATAAATTGATTAGAGCCAAAAGGCGTGGTCATATCGCAGGGAATAACAG
TTAAGAAATCAGCATTGAGAACAAGATTATATATTGTGACGACGGAATCTGTTTTAACAATGTTTTCGAT
GCTGATGCCATTTCGTTGTAGAGTGGTGAGTAATTCGCTGTAGTAGCCCATATTCGTTTGCGGCAACACC
CACTGTTCGTCTTTTAACGATTCCAGTGTGATGGTGCCGGTGCATGTTCGGGACTTGCTGGCTACCAGGA
CAAACTCTGATTCAAACAGCGGCTCGACATGCAGATCCTGTAGCTGCATTTCATTACTGAGCGTACCGAT
AGCAAAGTCCAGCCGCCCGTCGCGCAGGGCCGGCAGAAATGAAGAGAGCTGGGCTTCGTACATGGATACC
TGCGCTTTTGGAAAGACCTCTTTGAACTTATGAATCATATCGGACATGAAGGTAAAGCCAATCAGCGAAG
GAAAGCCAAACGAGACGTCGACAACGGTATTGCACGTCATACTGTTCATCTCGTTGATCATGTTTTTCAT
TTCGCGGGTGATAGATTCAGACCAGGAAAGCAGTACCTGTCCCGCTTCGGTCAACGTAACGCCGGTATTT
TTACGTACAATTAGCTCAACGCCAAAATAGGCCTCAACATCGCTAATGATTTTACTGACGGCGGGTTGGG
TTAACCCTAACGATTTTGCGGCAGAACCGATAGAACCACTTCTAATGACTTCCTGAAAGACCACCAAATG
CTGTGTTTTAGGGAGAACAAGAGTATTCA
Protein Sequence 
>gi|16766544|ref|NP_462159.1| DNA-binding transcriptional activator TdcA [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] MNTLVLPKTQHLVVFQEVIRSGSIGSAAKSLGLTQPAVSKIISDVEAYFGVELIVRKNTGVTLTEAGQVLLSWSESITREMKNMINEMNSMTCNTVVDVSFGFPSLIGFTFMSDMIHKFKEVFPKAQVSMYEAQLSSFLPALRDGRLDFAIGTLSNEMQLQDLHVEPLFESEFVLVASKSRTCTGTITLESLKDEQWVLPQTNMGYYSELLTTLQRNGISIENIVKTDSVVTIYNLVLNADFLTVIPCDMTTPFGSNQFITIPIQDTLPVARYAAVWSKNYRIKKAASVLVELAKQYSSYNGCRRRQLIEIE
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: tdcA mutant is less invasive of cultured epithelial cells and attenuated in mice (Kim et al., 2009).
COG COG0583K, under K: Transcription
References
Kim et al., 2009: Kim M, Lim S, Kim D, Choy HE, Ryu S. A tdcA mutation reduces the invasive ability of Salmonella enterica serovar typhimurium. Molecules and cells. 2009; 28(4); 389-395. [PubMed: 19812899].