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sopD

Victor ID 2770
Gene Name sopD
Sequence Strain (Species/Organism) Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
NCBI Gene ID 1254468
NCBI Protein GI 16766251
Locus Tag STM2945
Protein Accession NP_461866.1
Other Database IDs UniProtKB-ID: SOPD_SALTY
UniRef100: UniRef100_P40722
UniRef90: UniRef90_P40722
UniRef50: UniRef50_P40722
UniParc: UPI0000135CDE
EMBL: M23007
EMBL: AE006468
EMBL-CDS: AAA27049.1
EMBL-CDS: AAL21825.1
RefSeq_NT: NC_003197.1
GenomeReviews: AE006468_GR
KEGG: stm:STM2945
NMPDR: fig|99287.1.peg.2841
HOGENOM: HBG671701
OMA: RILNNIN
ProtClustDB: CLSK894379
BioCyc: STYP99287:STM2945-MONOMER
Taxonomy ID 99287
Gene Starting Position 3087147
Gene Ending Position 3088100
Gene Strand (Orientation) +
Protein Name secreted effector protein
DNA Sequence 
>gi|16763390:3087147-3088100 Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 chromosome, complete genome
TATGCCAGTCACTTTAAGCTTCGGTAATCATCAAAATTATACGCTTAATGAAAGTCGGCTTGCTCATCTG
TTAAGCGCAGATAAAGAAAAAGCAATCCATATGGGGGGTTGGGATAAAGTCCAGGATCATTTTAGAGCGG
AAAAAAAGGACCATGCGCTGGAAGTGTTACACTCCATCATTCACGGGCAGGGCCGTGGTGAACCTGGAGA
GATGGAAGTTAACGTAGAGGATATAAATAAAATTTACGCCTTTAAACGGCTACAACATCTGGCCTGCCCG
GCTCATCAAGATCTGTTTACTATCAAGATGGACGCTTCTCAGACACAATTTTTACTTATGGTCGGCGACA
CGGTGATCAGCCAAAGCAATATTAAGGACATCCTTAATATATCAGATGATGCAGTGATAGAATCTATGAG
TAGAGAGGAGAGACAATTATTTTTACAAATATGTGAGGTGATTGGTTCGAAGATGACCTGGCACCCGGAA
TTACTTCAGGAGTCGATTTCAACTCTACGAAAAGAAGTGACGGGAAATGCACAAATCAAAACGGCGGTTT
ATGAGATGATGCGTCCCGCAGAGGCTCCAGACCACCCGCTTGTCGAATGGCAGGACTCACTTACTGCAGA
TGAAAAATCAATGCTGGCCTGTATTAATGCCGGTAACTTTGAGCCTACGACTCAGTTTTGCAAAATAGGT
TATCAGGAGGTACAAGGTGAAGTCGCTTTTAGCATGATGCATCCGTGCATCTCCTATTTACTACATAGCT
ATTCACCGTTTTCAGAGTTTAAACCAACAAATTCTGGTTTTTTAAAAAAACTTAATCAGGATTATAACGA
CTATCATGCAAAAAAAATGTTTATTGATGTAATTCTTGAAAAACTATATCTAACCCATGAACGTTCTTTG
CACATTGGTAAAGATGGGTGCAGTCGTAATATATTACTGACATA
Protein Sequence 
>gi|16766251|ref|NP_461866.1| secreted effector protein SopD [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] MPVTLSFGNHQNYTLNESRLAHLLSADKEKAIHMGGWDKVQDHFRAEKKDHALEVLHSIIHGQGRGEPGEMEVNVEDINKIYAFKRLQHLACPAHQDLFTIKMDASQTQFLLMVGDTVISQSNIKDILNISDDAVIESMSREERQLFLQICEVIGSKMTWHPELLQESISTLRKEVTGNAQIKTAVYEMMRPAEAPDHPLVEWQDSLTADEKSMLACINAGNFEPTTQFCKIGYQEVQGEVAFSMMHPCISYLLHSYSPFSEFKPTNSGFLKKLNQDYNDYHAKKMFIDVILEKLYLTHERSLHIGKDGCSRNILLT
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: sopD mutants induce significantly less fluid accumulation in bovine ligated ileal loops than the wild-type (Zhang et al., 2002).
References
Zhang et al., 2002: Zhang S, Santos RL, Tsolis RM, Stender S, Hardt WD, Bäumler AJ, Adams LG. The Salmonella enterica serotype typhimurium effector proteins SipA, SopA, SopB, SopD, and SopE2 act in concert to induce diarrhea in calves. Infection and immunity. 2002; 70(7); 3843-3855. [PubMed: 12065528].