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invG from Salmonella enterica subsp. enterica serovar Typhimurium str. LT2

Victor ID 2767
Gene Name invG from Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
Sequence Strain (Species/Organism) Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
NCBI Gene ID 1254421
NCBI Protein GI 16766204
Locus Tag STM2898
Protein Accession NP_461819.1
Other Database IDs UniProtKB-ID: INVG_SALTY
UniRef100: UniRef100_P35672
UniRef90: UniRef90_P35672
UniRef50: UniRef50_P35672
UniParc: UPI000012D722
EMBL: X75302
EMBL: U08280
EMBL: AE006468
EMBL-CDS: CAA53049.1
EMBL-CDS: AAA74040.1
EMBL-CDS: AAL21778.1
RefSeq_NT: NC_003197.1
DIP: DIP-48517N
TCDB: 1.B.22.3.2
GenomeReviews: AE006468_GR
KEGG: stm:STM2898
NMPDR: fig|99287.1.peg.2795
HOGENOM: HBG640696
OMA: VFLIQPR
ProtClustDB: CLSK862854
BioCyc: STYP99287:STM2898-MONOMER
Taxonomy ID 99287
Gene Starting Position 3041596
Gene Ending Position 3043284
Gene Strand (Orientation) -
Protein Name outer membrane secretin precursor
DNA Sequence 
>gi|16763390:3041596-3043284 Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 chromosome, complete genome
ATCATTTAATTGCCTCCTGACCTCTATCCAGATAAACACGAACCCATTTCTGTAACTTATCGTCCCCACT
CCAGGCACCGCTTTGCTTCAGAATATTGTTTACCGATTCGCTGGCATCCGGCGTTAACGGGTCGACAATT
TCTTTTGGTTCAATCATGAACACACGAACAACATTACTTTTATTCTTACTGGAATAACGGAACAGGCTAC
CAATAAGCGGTAATTTGCCTAAAAACGGAATACTTTGGACAGTATCGGTATTTGCATCCCGTGTATAACC
CCCGACCAGCAAACTTTTTCCGTGCGGCACTCTCGCAATAGTGCTAATTAACGTTCGCCCGACTTCGGGT
AACGCATCTACGGAGGTGGTAGTATCAGATTGCGGCGTCTTATCGTTGCCATCTTCAATGTCCAGCGACA
TTTCTATCTGACCATCTGCGGAAAAACGGGGCAGCACTCGGATCATTGTTCCGTATGTTACATGCTCAAG
CGCCACATTACGTTCCCCAATCAGCTTGGTGTAAAACGTTCTGTTGTTATCAAAAATAGCGGGAACATTT
TCCTGAGTCAGTAATACCGGGCGCGAAACCACCGTCGCCTGTTTCTTCTCTTCTAACGCATTGACCGCGG
CGATGAATCGACTGCCATCGAGGGTACTTATTGAAGACTGGTTTAATGACACGCCAAGTTTGTCCCCAAT
AGTTATGCTGCCGCTCCATGAAGTGCCCAAACGCTCCAGATCGCTTTTATTAAGATCGACAATCCACAGG
GATAATTCTACGTGACGTTTGGCGACATCCAGCGCTTTAACCAGCATTTCGATAAAATGCACCTGCTCAG
CCGTTCCCTTTACTAACAAACTGTTGGTATCCGGATAGGCCACGATTTTAATATTGCCCGCCGCGGCATT
TTGCTTTAAAGCTTCCTGCAGACTCATGCCACCGGCATAATTTGCTGCTTTACCTTTTTCTCCATTCGCT
GAAAACGCTGGCATCGCCGGGGGTTCGCTACTGACAATATTACCTAAGGGTTGCTCTTCTCCCTGCAATA
ACCTTTCAATGGCCGTAGCAATACCGGGAATAACCATTTTCTGATCGCGCAGATTATAGGTACGATCGCC
CACGAAGGTATTGTTCAGACGCATCACCCCTATTTTCTGGCGTCCCAGCTCAATACCATCGTTTTGCTTG
TCCATCATGGTGGCGGCGTTGACCACCATATCAACATAGACGGGTGGCCCTGAAACATAGAATGTTCCTT
TACGGTTATCGCCACGTAGCGGGTAATTTTTGTTATATAAACCTGAGCGTTTTAGAAAATTGTTGAACTC
ATTGAGTGAGACGTTGCGTAAAGAAACCACGGCATTGCGCATTTCACTGGCGTCATAAATATAGATAGCC
TGCCCATCGAAATACCAAATCAGCCCCAGTTGTAGGGAAAGCTTCTCCAGTAATGCGTTAGGATCGTGAA
ACTCAAAGTTGCCCGTAATTTTTTTTCGTGCCGCCATTTTGCTAACAATGACAGGCTCCTTTAGCTGTAG
CGCCATGGCATCGAAAAATGTCCGCAGGCTATCGTCTTTCGCAACAAACCCACTTCCCGTTACAGGTATT
TTTTCACTAGAATAACCAGGTGTAACCAGAACAAGCGCGGCACATGCCAGCACTCTGGCCAAAAGAATAT
GTGTCTTCA
Protein Sequence 
>gi|16766204|ref|NP_461819.1| invasion protein InvG [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] MKTHILLARVLACAALVLVTPGYSSEKIPVTGSGFVAKDDSLRTFFDAMALQLKEPVIVSKMAARKKITGNFEFHDPNALLEKLSLQLGLIWYFDGQAIYIYDASEMRNAVVSLRNVSLNEFNNFLKRSGLYNKNYPLRGDNRKGTFYVSGPPVYVDMVVNAATMMDKQNDGIELGRQKIGVMRLNNTFVGDRTYNLRDQKMVIPGIATAIERLLQGEEQPLGNIVSSEPPAMPAFSANGEKGKAANYAGGMSLQEALKQNAAAGNIKIVAYPDTNSLLVKGTAEQVHFIEMLVKALDVAKRHVELSLWIVDLNKSDLERLGTSWSGSITIGDKLGVSLNQSSISTLDGSRFIAAVNALEEKKQATVVSRPVLLTQENVPAIFDNNRTFYTKLIGERNVALEHVTYGTMIRVLPRFSADGQIEMSLDIEDGNDKTPQSDTTTSVDALPEVGRTLISTIARVPHGKSLLVGGYTRDANTDTVQSIPFLGKLPLIGSLFRYSSKNKSNVVRVFMIEPKEIVDPLTPDASESVNNILKQSGAWSGDDKLQKWVRVYLDRGQEAIK
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: invG mutants have reduced ability to enter into cultured epithelial cells (Kaniga et al., 1994).
COG COG1450NU, under N: Cell motility; U: Intracellular trafficking, secretion, and vesicular transport
References
Kaniga et al., 1994: Kaniga K, Bossio JC, Galán JE. The Salmonella typhimurium invasion genes invF and invG encode homologues of the AraC and PulD family of proteins. Molecular microbiology. 1994; 13(4); 555-568. [PubMed: 7997169].