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invE from Salmonella enterica subsp. enterica serovar Typhimurium str. LT2

Victor ID 2766
Gene Name invE from Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
Sequence Strain (Species/Organism) Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
NCBI Gene ID 1254420
NCBI Protein GI 16766203
Locus Tag STM2897
Protein Accession NP_461818.1
Other Database IDs UniProtKB-ID: INVE_SALTY
UniRef100: UniRef100_P35671
UniRef90: UniRef90_Q56052
UniRef50: UniRef50_Q56052
UniParc: UPI000012D721
EMBL: M90714
EMBL: AE006468
EMBL: U08280
EMBL: X75302
EMBL-CDS: -
EMBL-CDS: AAL21777.1
EMBL-CDS: AAA74041.1
EMBL-CDS: CAA53050.2
RefSeq_NT: NC_003197.1
GenomeReviews: AE006468_GR
KEGG: stm:STM2897
HOGENOM: HBG470489
OMA: SRASHED
ProtClustDB: CLSK880516
BioCyc: STYP99287:STM2897-MONOMER
Taxonomy ID 99287
Gene Starting Position 3040481
Gene Ending Position 3041599
Gene Strand (Orientation) -
Protein Name invasion protein
DNA Sequence 
>gi|16763390:3040481-3041599 Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 chromosome, complete genome
ATTAAGACAGCTTTTCAATAGTACGACGCTGTTCTGCCATTTCATGCTTGTAGGCAATATCGGTCATACT
ACGTAACGCCATTAACAATTCTTCCTGCCAATATTCTTCATAAAAGAGTGAAGAGGGTATGGCTTTACAT
ACTTGATAAAATATCTGCAAAAAGGATGCATGTTCTTTATGACTAAGCAATAACGCATTCAAACCTATAA
TATCGGCTAACAGCGAATCCACTTCATGTGGCTGTTGCAATAGCGAAAGCATCAGTAGTAACCACGACGA
CTCCTCCGCATTAAACGCTTTGGTAAACGAATACGACAACAATGTACTCACAAACAGTAGGTCAGCGGAG
CGCAACATTTTAAGTTGCGTCAGGCGTCGTAAAAGCTGGCCAAACTCCAGGCGCGAACAGCTGGCGTCAT
TCGCGTCAATATCGGTTAATAGCGAACCCTCAATAAAATCCAGTACCACCAGTCGACGTTGATAGCCATA
ACTGGCTATCCAGTCAGAGTAAATCTCCACTTCATGTGATTCACTCTGGATAAATTGCCGATAGCTGGCG
CGCAATAAGCCTGGTTTTAACGATAATGTTTTCCCAAAAAGCCGGGCCTTCAACGCACAATTAATCCCTG
CCTTGAGGGTCTTCGGATCGGTTTGCTCTTCAACGTGCTTAAGTAACGACTCCAGCTTTTTCCGCACGAT
CTCTTCCAGGTCTTTACGACGAAGCAATTCGCGTAACACAAGGACTAAATCACTGGGGTCAGGAAATAAG
CTACGCGCCTGACGTAAAAAATCTTCTAACGCGCCGCCATGTACGCTAATTAGCTTTAAGATTTGCTTCG
CCTTCGGTAAAGCCTCATCCTCCAGCACGCGTTCAAAACTGTTAGATAAATTACTGGATTTTTTTTCATA
ATCGCGACGGTTACGAAATTGCGCCAGCGCCGCTGACATTTCGTCCGTCGACTGGACAAATTTTTGTACT
TCCGCCCCTGGAGACGAATCCTCTGCGGCCTGTTGTATTTCCGCCTGTTGCGCATCAGTATGCTGGGTCG
CATCCTGATGAGATGTCTGCCGGGACAATATTCTGGAAAATGAAATACCGGAGGTTGAGCCAGGAATCA
Protein Sequence 
>gi|16766203|ref|NP_461818.1| invasion protein InvE [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] MIPGSTSGISFSRILSRQTSHQDATQHTDAQQAEIQQAAEDSSPGAEVQKFVQSTDEMSAALAQFRNRRDYEKKSSNLSNSFERVLEDEALPKAKQILKLISVHGGALEDFLRQARSLFPDPSDLVLVLRELLRRKDLEEIVRKKLESLLKHVEEQTDPKTLKAGINCALKARLFGKTLSLKPGLLRASYRQFIQSESHEVEIYSDWIASYGYQRRLVVLDFIEGSLLTDIDANDASCSRLEFGQLLRRLTQLKMLRSADLLFVSTLLSYSFTKAFNAEESSWLLLMLSLLQQPHEVDSLLADIIGLNALLLSHKEHASFLQIFYQVCKAIPSSLFYEEYWQEELLMALRSMTDIAYKHEMAEQRRTIEKLS
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: invE mutants were unable to penetrate Henle-407 human intestinal cells and Madin-Darby canine kidney cells (Ginocchio et al., 1992).
References
Ginocchio et al., 1992: Ginocchio C, Pace J, Galán JE. Identification and molecular characterization of a Salmonella typhimurium gene involved in triggering the internalization of salmonellae into cultured epithelial cells. Proceedings of the National Academy of Sciences of the United States of America. 1992; 89(13); 5976-5980. [PubMed: 1631083].