Search: for Help
About
Introduction
Statistics
Your PHIDIAS
Register or Login
Philert
Submission
Curated Data
Victors
BBP (Brucella)
Phinfo
Phinet
HazARD
Data Analysis
Phigen
Pacodom
BLAST
Help & Documents
Documents
FAQs
Links
Acknowledgements
Disclaimer
Contact Us
UMMS Logo

spaS from Salmonella enterica subsp. enterica serovar Typhimurium str. LT2

Victor ID 2756
Gene Name spaS from Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
Sequence Strain (Species/Organism) Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
NCBI Gene ID 1254410
NCBI Protein GI 16766193
Locus Tag STM2887
Protein Accession NP_461808.1
Other Database IDs UniProtKB-ID: SPAS_SALTY
UniRef100: UniRef100_P40702
UniRef90: UniRef90_P40702
UniRef50: UniRef50_P40702
UniParc: UPI0000135DA7
EMBL: X73525
EMBL: AE006468
EMBL-CDS: CAA51927.1
EMBL-CDS: AAL21767.1
RefSeq_NT: NC_003197.1
PDB: 3C01
MEROPS: N06.002
GenomeReviews: AE006468_GR
KEGG: stm:STM2887
HOGENOM: HBG529770
OMA: QPNPGAY
ProtClustDB: PRK08156
BioCyc: STYP99287:STM2887-MONOMER
Taxonomy ID 99287
Gene Starting Position 3031532
Gene Ending Position 3032602
Gene Strand (Orientation) -
Protein Name surface presentation of antigens protein SpaS
DNA Sequence 
>gi|16763390:3031532-3032602 Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 chromosome, complete genome
CTCAATGCCGTACCTCGTTTTCTTGTGGCTGAATAACGTCTTTGCCCGCGTTTTCTACCTCTTCCAGCCA
AACCAGAAGACGTAAAACTTCATCAATTTCTTCCAGACTCACCAGATCATAACGGCGATGGGTTTTGAAA
AGACTGCGCGCCAGTTTGATATCGACGATCACAGGTACGCCAACCTTCTCCGCATAGGCGCGGACGGCCA
GTGCGCGCTGATTCGTTTCATACACCGAGATCATCGGAATCGGCATCAATTCGGGTTTAAAATAAATCCC
GATCGTAATATGCGTGGGGTTGGCAACAATCAGGCGTGAGTTTTCAATATCAGATTTCACCTGTTCAGAC
AGAATTTCCATATGAACTTCACGTCTTTTAGATTTAACCTCTGGGTTCCCTTCCTGCTCCTTCATTTCAC
GCTTCACTTCTTCCTTATCCATTTTCATATCTTTCATGGTCAGGAAATATTCCGCAATAGCATCCAATAA
TAAGACAATCAATGCGCAAGCAAGGCAAGTTAATACCAATGCGAGGAGAAGTTCACGCCAAATGACGGCA
ATACCTACAATATTGCCATTTAGCTGAGAAAAGATTTCAACCTTATATTTCTTCCAGCAAATGATGGCGG
CCACCACAAAGGATGAGAGATACAGTAGGGTTTTGACCGTATCTTTAACCGTGCGCATACTAAAAAGTTT
TTTTGCCCCTTCTACCGGGTTTAACGCCGATAAATTAGGCTTTAATGCTTCTGTCGCCAGCACAAAACCG
GCCTGTAATAACGCCGGTAATGCGGAACACACTAAGCAGAGCAGCATAAATGGAATCAGATATTTTAACC
CTATCCCAAAAACGGCCAAACTGTAGTCAGCCATGCTCTGATCAAAATTATCCGCAATAATGATCTTAAT
TATCCCCATAAACTCATTAAATGAGCCATACGACACCAGATAGGCAATTCCTCCCAGCGTCAGGCAGGCG
ATAATGAGATCTTTACTTTTAAATGACTGGCCTTTTTTAGCGGAGTCTTCCAGCCGTTTTTTAGTCGGTT
TTTCTGTTTTATTCGAGGACA
Protein Sequence 
>gi|16766193|ref|NP_461808.1| surface presentation of antigens protein SpaS [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] MSSNKTEKPTKKRLEDSAKKGQSFKSKDLIIACLTLGGIAYLVSYGSFNEFMGIIKIIIADNFDQSMADYSLAVFGIGLKYLIPFMLLCLVCSALPALLQAGFVLATEALKPNLSALNPVEGAKKLFSMRTVKDTVKTLLYLSSFVVAAIICWKKYKVEIFSQLNGNIVGIAVIWRELLLALVLTCLACALIVLLLDAIAEYFLTMKDMKMDKEEVKREMKEQEGNPEVKSKRREVHMEILSEQVKSDIENSRLIVANPTHITIGIYFKPELMPIPMISVYETNQRALAVRAYAEKVGVPVIVDIKLARSLFKTHRRYDLVSLEEIDEVLRLLVWLEEVENAGKDVIQPQENEVRH
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: spaS mutant was 30-fold reduced for invasion into HEp-2 cells when compared with the wild-type strain (Darwin and Miller, 2000).
COG COG1377NU, under N: Cell motility; U: Intracellular trafficking, secretion, and vesicular transport
References
Darwin and Miller, 2000: Darwin KH, Miller VL. The putative invasion protein chaperone SicA acts together with InvF to activate the expression of Salmonella typhimurium virulence genes. Molecular microbiology. 2000; 35(4); 949-960. [PubMed: 10692170].