Search: for Help
About
Introduction
Statistics
Your PHIDIAS
Register or Login
Philert
Submission
Curated Data
Victors
BBP (Brucella)
Phinfo
Phinet
HazARD
Data Analysis
Phigen
Pacodom
BLAST
Help & Documents
Documents
FAQs
Links
Acknowledgements
Disclaimer
Contact Us
UMMS Logo

sicA

Victor ID 2755
Gene Name sicA
Sequence Strain (Species/Organism) Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
NCBI Gene ID 1254409
NCBI Protein GI 16766192
Locus Tag STM2886
Protein Accession NP_461807.1
Other Database IDs UniProtKB-ID: SICA_SALTY
UniRef100: UniRef100_P69064
UniRef90: UniRef90_P69064
UniRef50: UniRef50_P69064
UniParc: UPI000005A36D
EMBL: U25631
EMBL: AE006468
EMBL: X73525
EMBL-CDS: AAA75168.1
EMBL-CDS: AAL21766.1
EMBL-CDS: CAA51928.1
RefSeq_NT: NC_003197.1
PDB: 1OOR
GenomeReviews: AE006468_GR
KEGG: stm:STM2886
HOGENOM: HBG371864
OMA: ASKFERA
ProtClustDB: CLSK862849
BioCyc: STYP99287:STM2886-MONOMER
Taxonomy ID 99287
Gene Starting Position 3030897
Gene Ending Position 3031394
Gene Strand (Orientation) -
Protein Name secretion chaperone
DNA Sequence 
>gi|16763390:3030897-3031394 Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 chromosome, complete genome
ATTATTCCTTTTCTTGTTCACTGTGCTGCTCTGTCTCCGCCGTTTTTAGCGCCTCCAGATAGACCAACGC
TTTTGCCCGCAGAGACTCATCTTCAGTACGTTCATTGACAAGTTCAAAACACTGTCTGGCTTTTGCTGCC
TTACGCATTAATAATTGACACTGCCCGGTAAAAAAAACGGGGCGATAATCATTTTTAAGTAACGTAAACG
CTACTGCATAAAGGTCACATGCTTTCTGAAATTGTTTTTTCAGTTGGCATACTGCCGCCAGTCCCATGGT
GTAATCGGGATTGTAAAAATCATAAATGCATAAGAAACGAAAGAACGTCTCAGCTTCATCCAGTCGTCCC
TGGTTATAAAACTCATAAGCATGAGCATATAAACCGTCCATCATATCTTGAGGGATCCCATGAACGTCTT
TTAGCGTGGCGCCTTCACTAACGGCATCCCAAATCATTTCCGCAACACGTTCTTCGCTGACATTATTTTG
ATAATCCA
Protein Sequence 
>gi|16766192|ref|NP_461807.1| chaperone protein SicA [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] MDYQNNVSEERVAEMIWDAVSEGATLKDVHGIPQDMMDGLYAHAYEFYNQGRLDEAETFFRFLCIYDFYNPDYTMGLAAVCQLKKQFQKACDLYAVAFTLLKNDYRPVFFTGQCQLLMRKAAKARQCFELVNERTEDESLRAKALVYLEALKTAETEQHSEQEKE
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: sicA mutants are unable to invade cultured epithelial cells (Kaniga et al., 1995).
References
Kaniga et al., 1995: Kaniga K, Tucker S, Trollinger D, Galán JE. Homologs of the Shigella IpaB and IpaC invasins are required for Salmonella typhimurium entry into cultured epithelial cells. Journal of bacteriology. 1995; 177(14); 3965-3971. [PubMed: 7608068].