Search: for Help
About
Introduction
Statistics
Your PHIDIAS
Register or Login
Philert
Submission
Curated Data
Victors
BBP (Brucella)
Phinfo
Phinet
HazARD
Data Analysis
Phigen
Pacodom
BLAST
Help & Documents
Documents
FAQs
Links
Acknowledgements
Disclaimer
Contact Us
UMMS Logo

hilA

Victor ID 2750
Gene Name hilA
Sequence Strain (Species/Organism) Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
NCBI Gene ID 1254399
NCBI Protein GI 16766182
Locus Tag STM2876
Protein Accession NP_461797.1
Other Database IDs UniProtKB-ID: HILA_SALTY
UniRef100: UniRef100_P43015
UniRef90: UniRef90_Q5PEB1
UniRef50: UniRef50_P43015
UniParc: UPI000012D0B2
EMBL: U25352
EMBL: AE006468
EMBL-CDS: AAD12579.1
EMBL-CDS: AAL21756.1
RefSeq_NT: NC_003197.1
GenomeReviews: AE006468_GR
KEGG: stm:STM2876
HOGENOM: HBG469236
OMA: IAPQLER
ProtClustDB: PRK12370
BioCyc: STYP99287:STM2876-MONOMER
Taxonomy ID 99287
Gene Starting Position 3019855
Gene Ending Position 3021516
Gene Strand (Orientation) +
Protein Name invasion protein regulator
DNA Sequence 
>gi|16763390:3019855-3021516 Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 chromosome, complete genome
CATGCCACATTTTAATCCTGTTCCTGTATCGAATAAAAAATTCGTCTTTGATGATTTCATACTCAACATG
GACGGCTCCCTGCTACGCTCAGAAAAGAAAGTCAATATTCCGCCAAAAGAATATGCCGTTCTGGTCATCC
TGCTCGAAGCCGCCGGCGAGATTGTGAGTAAAAACACCTTACTGGACCAGGTATGGGGCGACGCGGAAGT
TAACGAAGAATCTCTTACCCGCTGTATTTATGCCTTACGACGTATTCTGTCGGAAGATAAAGAGCATCGT
TACATTGAAACACTGTACGGACAGGGCTATCGGTTTAATCGTCCGGTCGTAGTGGTGTCTCCGCCAGCGC
CGCAACCTACGACTCATACATTGGCGATACTTCCTTTTCAGATGCAGGATCAGGTTCAATCCGAGAGTCT
GCATTACTCTATCGTGAAGGGATTATCGCAGTATGCGCCCTTTGGCCTGAGCGTGCTGCCGGTGACCATT
ACGAAGAACTGCCGCAGTGTTAAGGATATTCTTGAGCTCATGGATCAATTACGCCCCGATTATTATATCT
CCGGGCAGATGATACCCGATGGTAATGATAATATTGTACAGATTGAGATAGTTCGGGTTAAAGGTTATCA
CCTGCTGCACCAGGAAAGCATTAAGTTGATAGAACACCAACCCGCTTCTCTCTTGCAAAACAAAATTGCG
AATCTTTTGCTCAGATGTATTCCCGGACTTCGCTGGGACACAAAGCAGATTAGCGAGCTAAATTCGATTG
ACAGTACTATGGTTTACTTACGCGGTAAGCATGAGTTAAATCAATACACCCCCTATAGCTTACAGCAAGC
GCTTAAATTGCTGACTCAATGCGTTAACATGTCGCCAAACAGCATTGCGCCTTACTGTGCGCTGGCAGAA
TGCTACCTCAGCATGGCGCAAATGGGGATTTTTGATAAACAAAACGCTATGATCAAAGCTAAAGAACATG
CGATTAAGGCGACAGAGCTGGACCACAATAATCCACAAGCTTTAGGATTACTGGGGCTAATTAATACGAT
TCACTCAGAATACATCGTCGGGAGTTTGCTATTCAAACAAGCTAACTTACTTTCGCCCATTTCTGCAGAT
ATTAAATATTATTATGGCTGGAATCTTTTCATGGCTGGTCAGTTGGAGGAGGCCTTACAAACGATTAACG
AGTGTTTAAAATTGGACCCAACGCGCGCAGCCGCAGGGATCACTAAGCTGTGGATTACCTATTATCATAC
CGGTATTGATGATGCTATACGTTTAGGCGATGAATTACGCTCACAACACCTGCAGGATAATCCAATATTA
TTAAGTATGCAGGTTATGTTTCTTTCGCTTAAAGGTAAACATGAACTGGCACGAAAATTAACTAAAGAAA
TATCCACGCAGGAAATAACAGGACTTATTGCTGTTAATCTTCTTTACGCTGAATATTGTCAGAATAGTGA
GCGTGCCTTACCGACGATAAGAGAATTTCTGGAAAGTGAACAGCGTATAGATAATAATCCGGGATTATTA
CCGTTAGTGCTGGTTGCCCACGGCGAAGCTATTGCCGAGAAAATGTGGAATAAATTTAAAAACGAAGACA
ATATTTGGTTCAAAAGATGGAAACAGGATCCCCGCTTGATTAAATTACGGTA
Protein Sequence 
>gi|16766182|ref|NP_461797.1| transcriptional regulator HilA [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] MPHFNPVPVSNKKFVFDDFILNMDGSLLRSEKKVNIPPKEYAVLVILLEAAGEIVSKNTLLDQVWGDAEVNEESLTRCIYALRRILSEDKEHRYIETLYGQGYRFNRPVVVVSPPAPQPTTHTLAILPFQMQDQVQSESLHYSIVKGLSQYAPFGLSVLPVTITKNCRSVKDILELMDQLRPDYYISGQMIPDGNDNIVQIEIVRVKGYHLLHQESIKLIEHQPASLLQNKIANLLLRCIPGLRWDTKQISELNSIDSTMVYLRGKHELNQYTPYSLQQALKLLTQCVNMSPNSIAPYCALAECYLSMAQMGIFDKQNAMIKAKEHAIKATELDHNNPQALGLLGLINTIHSEYIVGSLLFKQANLLSPISADIKYYYGWNLFMAGQLEEALQTINECLKLDPTRAAAGITKLWITYYHTGIDDAIRLGDELRSQHLQDNPILLSMQVMFLSLKGKHELARKLTKEISTQEITGLIAVNLLYAEYCQNSERALPTIREFLESEQRIDNNPGLLPLVLVAHGEAIAEKMWNKFKNEDNIWFKRWKQDPRLIKLR
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: hilA mutants have reduced ability to invade HEp-2 cells and to colonize murine Peyer’s patches (Tsolis et al., 1999).
COG COG3710K, under K: Transcription
References
Tsolis et al., 1999: Tsolis RM, Adams LG, Ficht TA, Bäumler AJ. Contribution of Salmonella typhimurium virulence factors to diarrheal disease in calves. Infection and immunity. 1999; 67(9); 4879-4885. [PubMed: 10456944].