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prgI

Victor ID 2747
Gene Name prgI
Sequence Strain (Species/Organism) Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
NCBI Gene ID 1254396
NCBI Protein GI 16766179
Locus Tag STM2873
Protein Accession NP_461794.1
Other Database IDs UniProtKB-ID: PRGI_SALTY
UniRef100: UniRef100_P41784
UniRef90: UniRef90_P41784
UniRef50: UniRef50_P41784
UniParc: UPI00001321A1
EMBL: U21676
EMBL: AE006468
EMBL-CDS: AAB60189.1
EMBL-CDS: AAL21753.1
RefSeq_NT: NC_003197.1
PDB: 2JOW
PDB: 2KV7
PDB: 2X9C
GenomeReviews: AE006468_GR
KEGG: stm:STM2873
HOGENOM: HBG637005
OMA: KDWTLSS
ProtClustDB: CLSK862852
BioCyc: STYP99287:STM2873-MONOMER
Taxonomy ID 99287
Gene Starting Position 3016074
Gene Ending Position 3016316
Gene Strand (Orientation) -
Protein Name needle complex major subunit
DNA Sequence 
>gi|16763390:3016074-3016316 Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 chromosome, complete genome
ATTAACGGAAGTTCTGAATAATGGCAGCATCAATATCCTTAAAGACTTTTACCGTGTTCGATTGCGCGTT
ACGGTACAAGTTATATTCCGAGAGCTTACTCTGATACGCCGCCAGTAGCGCCGGATCGGAGGGTTTTGCT
GCTAATTTATCCAGCGCCTCTGTTACCTGCGTTTGTAGATTATCAACGCCCGTATCAAATTTTGCTGAGA
CGTCATCCAGATAGCCTGACCAAGGTGTTGCCA
Protein Sequence 
>gi|16766179|ref|NP_461794.1| secretion system protein PrgI [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] MATPWSGYLDDVSAKFDTGVDNLQTQVTEALDKLAAKPSDPALLAAYQSKLSEYNLYRNAQSNTVKVFKDIDAAIIQNFR
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: prgI mutants are attenuated in their ability to invade HEp-2 cells (Klein et al., 2000).
References
Klein et al., 2000: Klein JR, Fahlen TF, Jones BD. Transcriptional organization and function of invasion genes within Salmonella enterica serovar Typhimurium pathogenicity island 1, including the prgH, prgI, prgJ, prgK, orgA, orgB, and orgC genes. Infection and immunity. 2000; 68(6); 3368-3376. [PubMed: 10816487].