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prgK from Salmonella enterica subsp. enterica serovar Typhimurium str. LT2

Victor ID 2745
Gene Name prgK from Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
Sequence Strain (Species/Organism) Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
NCBI Gene ID 1254394
NCBI Protein GI 16766177
Locus Tag STM2871
Protein Accession NP_461792.1
Other Database IDs UniProtKB-ID: PRGK_SALTY
UniRef100: UniRef100_P41786
UniRef90: UniRef90_P41786
UniRef50: UniRef50_P41786
UniParc: UPI00001321A3
EMBL: U21676
EMBL: AE006468
EMBL-CDS: AAB60191.1
EMBL-CDS: AAL21751.1
RefSeq_NT: NC_003197.1
GenomeReviews: AE006468_GR
KEGG: stm:STM2871
HOGENOM: HBG671305
OMA: HISVIAI
ProtClustDB: CLSK862853
BioCyc: STYP99287:STM2871-MONOMER
Taxonomy ID 99287
Gene Starting Position 3014995
Gene Ending Position 3015753
Gene Strand (Orientation) -
Protein Name needle complex inner membrane lipoprotein
DNA Sequence 
>gi|16763390:3014995-3015753 Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 chromosome, complete genome
CCTATTCATTTGACGATTTCGCCTTATCATCAGCCGTTATGCCTTTCTTATTGCGGGCATAATGGTTTTT
GTAATACCAGACGCCAAAGCCTGCTGACATCACGGATAACAAAATAATCAAAACAATCCAACTGGTTGCA
AAAGAATTACGTTTTACTGGTGTGCCGGGAGCCTGTAATTGGGCATCAGAACGTTCTGACAACACAACAG
AAATGTTGTCATAATCCACATCGGCAAAACTATTCTTTAAGAAACGCTTGATATCGCTGATCTGATGCGC
AAGCGGCGAACCTCGTTCATATACGGCTAATGCCGACAGATGAACAGGTTTTGGCGGGCGGCCATTTTCA
CCAGCATCAATATCATAACTAATATGGACCCTGGCGGAGAGCACGCCCTCCATCGTCTGTAATGACTGTT
CCAGTCGCTGTTCAATAGCCGAATATAACCTGGCCTTTTCAGCTCGCGGAGACGATACCAGCGAATCCGC
CGGGAACATCTGCGCTATTTCCACCCGTGGCCGGGGAGGAAGCTGATAAGTTTTAATCCAGTACACCGCA
GCGGTAAAATCAGGCTCAGCAACGGTAATGCTATAGCCCAATTTTCCGCTATCAATTTTATTCGCCTCTA
TATTGTGCATTTGCAGAACGGCAATGACCTCATTAGCCTGTTCCTGGTCCAGTCCTTTTAAAAGATCCTT
ATCCTTACAGCCGGCAAGGGTCATTACCAGCAGAAAAGTATATAGATATCGACGAATCA
Protein Sequence 
>gi|16766177|ref|NP_461792.1| secretion system lipoprotein PrgK [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] MIRRYLYTFLLVMTLAGCKDKDLLKGLDQEQANEVIAVLQMHNIEANKIDSGKLGYSITVAEPDFTAAVYWIKTYQLPPRPRVEIAQMFPADSLVSSPRAEKARLYSAIEQRLEQSLQTMEGVLSARVHISYDIDAGENGRPPKPVHLSALAVYERGSPLAHQISDIKRFLKNSFADVDYDNISVVLSERSDAQLQAPGTPVKRNSFATSWIVLIILLSVMSAGFGVWYYKNHYARNKKGITADDKAKSSNE
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: prgK mutants are attenuated in their ability to invade HEp-2 cells (Klein et al., 2000).
COG COG4669U, under U: Intracellular trafficking, secretion, and vesicular transport
References
Klein et al., 2000: Klein JR, Fahlen TF, Jones BD. Transcriptional organization and function of invasion genes within Salmonella enterica serovar Typhimurium pathogenicity island 1, including the prgH, prgI, prgJ, prgK, orgA, orgB, and orgC genes. Infection and immunity. 2000; 68(6); 3368-3376. [PubMed: 10816487].