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orgA from Salmonella enterica subsp. enterica serovar Typhimurium str. LT2

Victor ID 2744
Gene Name orgA from Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
Sequence Strain (Species/Organism) Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
NCBI Gene ID 1254393
NCBI Protein GI 16766176
Locus Tag STM2870
Protein Accession NP_461791.1
Other Database IDs UniProtKB-ID: ORGA_SALTY
UniRef100: UniRef100_P58653
UniRef90: UniRef90_P58653
UniRef50: UniRef50_P58653
UniParc: UPI0000130E73
EMBL: L33855
EMBL: AE006468
EMBL: U21676
EMBL-CDS: AAA72055.1
EMBL-CDS: AAL21750.1
EMBL-CDS: AAB60192.1
RefSeq_NT: NC_003197.1
GenomeReviews: AE006468_GR
KEGG: stm:STM2870
HOGENOM: HBG685689
OMA: AAPMNPL
ProtClustDB: CLSK894362
BioCyc: STYP99287:STM2870-MONOMER
Taxonomy ID 99287
Gene Starting Position 3014424
Gene Ending Position 3015023
Gene Strand (Orientation) -
Protein Name needle complex assembly protein
DNA Sequence 
>gi|16763390:3014424-3015023 Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 chromosome, complete genome
CTCAACAGGCGAAAGCGGGGACGGTATTGGGATATTTTTGAGCATATTGTAAGGCCAGTAGCAAAATTGA
CATTTCTACAGCATCCTGCTTCAATGCCTCCTCAATAAATGGAGGAAAAAGCAAAGGAAAACGCTGTGCT
AAAGATTCAGGTAAAAATTCATTTAGGGCATTTAACTGTGCATACCCGACGCTAAGTAAAAACCGGTGAT
TCGGCGCCTTATTGCAGACAGATAAACTTGTTCCCTGATGCATTGCCAAAAATGCTTGCGCCCAATCCGG
CAGGCCAAGCAAGGCTCCCTGCCTTGCCAGATCGGCTCTCAGTTTATGGCAACCGAGTAAATACGCTACT
TGCGGCAGTCGGCGCCACTGACGCAGCCACAGCTGCGTCAGTGAGTTTTGAATACACTCCTTTTCTCCGT
TCTTAAGCCGCCATGCCGCCAGTATTAACTCATTTGCCGCCGCCCTGGCGGCGGGTCTGACAATCATTTC
CGGCGCTATCTGCAACCGCTGAGGATGGATATACGATAACGGATCAAAAATGATTCTTTGCCAGATAATG
GGTAATGGCTGCCTATTCATTTGACGATTTCGCCTTATCA
Protein Sequence 
>gi|16766176|ref|NP_461791.1| oxygen-regulated invasion protein OrgA [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] MIRRNRQMNRQPLPIIWQRIIFDPLSYIHPQRLQIAPEMIVRPAARAAANELILAAWRLKNGEKECIQNSLTQLWLRQWRRLPQVAYLLGCHKLRADLARQGALLGLPDWAQAFLAMHQGTSLSVCNKAPNHRFLLSVGYAQLNALNEFLPESLAQRFPLLFPPFIEEALKQDAVEMSILLLALQYAQKYPNTVPAFAC
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: orgA mutants are attenuated in their ability to invade HEp-2 cells (Klein et al., 2000).
References
Klein et al., 2000: Klein JR, Fahlen TF, Jones BD. Transcriptional organization and function of invasion genes within Salmonella enterica serovar Typhimurium pathogenicity island 1, including the prgH, prgI, prgJ, prgK, orgA, orgB, and orgC genes. Infection and immunity. 2000; 68(6); 3368-3376. [PubMed: 10816487].