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orgB

Victor ID 2743
Gene Name orgB
Sequence Strain (Species/Organism) Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
NCBI Gene ID 1254392
NCBI Protein GI 16766175
Locus Tag STM2869
Protein Accession NP_461790.1
Other Database IDs UniProtKB-ID: ORGB_SALTY
UniRef100: UniRef100_P58654
UniRef90: UniRef90_P58654
UniRef50: UniRef50_P58654
UniParc: UPI0000130E74
EMBL: L33855
EMBL: AE006468
EMBL-CDS: AAA72055.1
EMBL-CDS: AAL21749.1
RefSeq_NT: NC_003197.1
GenomeReviews: AE006468_GR
KEGG: stm:STM2869
HOGENOM: HBG415819
OMA: ENRETET
ProtClustDB: CLSK894361
BioCyc: STYP99287:STM2869-MONOMER
Taxonomy ID 99287
Gene Starting Position 3013787
Gene Ending Position 3014467
Gene Strand (Orientation) -
Protein Name needle complex export protein
DNA Sequence 
>gi|16763390:3013787-3014467 Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 chromosome, complete genome
ATCACCTTATAACCTCCGCTTGCGTTTTTGTCTTCCATTCATCAATAAGTGCGTTAATGGCGTTATCAGA
AATTGTCCGGCAGTCTTGTGGAAGTTCATCAAGATGATGCTTAATGACGCCTACTGCCGTTTCAACAAAT
TGTTCAGGTGAAAATTCTGCGATCTGATCGCCGCAACTCATGATAAAGCGCTGTTCCTGGTGATATTTAA
GATTAAAAGTGCCTGGCCAGTTCTCCATAAGCAACACCATCAGTTTTTGGTGATCTTTTTTCGCATTAAC
TGGCAGTGTTAAAAAAAGTTGCCCCTCAGGCTTATCGAAATCCCTTAGCCACTCATCCAGGACGGTTAAA
AGCGTTTCGGGATGGTCGACCGCAGCTGAAAATAACTCGCGGGCATAAATCTGTATTTTTTCCATCCACT
TCCAGGCCATTGTCTGATTATCAGTAAGATAAGCGGCGACCTGCTGTAACGCGTCTATCATTCCCTGCTC
GTAACCTTCCTGATAGGCGTACATCCGCAAGGTCTTTGCCTCTTCTTCCGCCTCTCGCAAAATACGCTTA
GCCCGTTGATGCGCCTGCTGTTCTAATCTTTCAATAGAGAAATAACGTTCCAGCGTTTTACGCTTTATCA
GTATCCCCTCAACAGGCGAAAGCGGGGACGGTATTGGGATATTTTTGAGCA
Protein Sequence 
>gi|16766175|ref|NP_461790.1| oxygen-regulated invasion protein OrgB [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] MLKNIPIPSPLSPVEGILIKRKTLERYFSIERLEQQAHQRAKRILREAEEEAKTLRMYAYQEGYEQGMIDALQQVAAYLTDNQTMAWKWMEKIQIYARELFSAAVDHPETLLTVLDEWLRDFDKPEGQLFLTLPVNAKKDHQKLMVLLMENWPGTFNLKYHQEQRFIMSCGDQIAEFSPEQFVETAVGVIKHHLDELPQDCRTISDNAINALIDEWKTKTQAEVIR
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: orgB mutants are attenuated in their ability to invade HEp-2 cells (Klein et al., 2000).
References
Klein et al., 2000: Klein JR, Fahlen TF, Jones BD. Transcriptional organization and function of invasion genes within Salmonella enterica serovar Typhimurium pathogenicity island 1, including the prgH, prgI, prgJ, prgK, orgA, orgB, and orgC genes. Infection and immunity. 2000; 68(6); 3368-3376. [PubMed: 10816487].