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hilC

Victor ID 2742
Gene Name hilC
Sequence Strain (Species/Organism) Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
NCBI Gene ID 1254390
NCBI Protein GI 16766173
Locus Tag STM2867
Protein Accession NP_461788.1
Other Database IDs UniProtKB-ID: SIRC_SALTY
UniRef100: UniRef100_Q9R3W3
UniRef90: UniRef90_Q8Z4A6
UniRef50: UniRef50_Q8Z4A6
UniParc: UPI00001359B0
EMBL: AF148689
EMBL: AF124397
EMBL: AF134856
EMBL: AE006468
EMBL-CDS: AAD37784.1
EMBL-CDS: AAD21080.1
EMBL-CDS: AAD32202.1
EMBL-CDS: AAL21747.1
RefSeq_NT: NC_003197.1
GenomeReviews: AE006468_GR
KEGG: stm:STM2867
NMPDR: fig|99287.1.peg.2765
HOGENOM: HBG673163
OMA: DFIHRIS
ProtClustDB: CLSK894359
BioCyc: STYP99287:STM2867-MONOMER
Taxonomy ID 99287
Gene Starting Position 3012106
Gene Ending Position 3012993
Gene Strand (Orientation) -
Protein Name invasion regulatory protein
DNA Sequence 
>gi|16763390:3012106-3012993 Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 chromosome, complete genome
ATCAATGGTTCATTGTACGCATAAAGCTAAGCGGTGTAATCTTAAAATGCCGTTTAAAAATAGCGATAAA
ATAAGAAGGCGTATCATAGCCACACATCGTCGCGACTTGTGAAATATTTCCAGCCCCCATACGTAATAAT
TTTATAGCCTGATTCATACGAGCATCCAGGTATATTTTACTAAAACTCACCTCTTCAGCGGCCAGTTTTC
GCTTCAGACTTGATACGCTCATAAACAGCTTTCCTGCCACCTCAGCCTGTGACCATTTGCGGGTGAGATC
GCTGATAATAATGTTATAAACTTTCTCTTTTGTCGTAATTTTTATTGCTCGCTCAAGGAAATCAAACCCA
CCGGGCTTACGTACAAATGCCGATATAAGATACATCAATGAGAAATATGAATAATCATGATCATCAATAC
TCACATTACTACAAACCCGTGGACATGCCACACCATGCAAAATAGAGTCAAAAGTATCACTCATCCCTGG
CAACAAGTCCGCATGAAAAAAATACTTTGGTTTCGTTTTTAATGATAGCTCTCGATCATTATAGTTTCTT
GTACTGTAAAAAACTTTGTAGAATTTTTGCATTAAGTCATAGGAAACTTCCAGTGAAGAAAAATCAATAT
GCCCTTCTATTTCGCTCATACTAAGCGTGATTGTTTGATCTTTTTCCAATAAAAATAAACACGGCGCAGA
TCGTTCGATGAACTCCCCAAATTCGTTTTCAATTCGCAAACTGCCTTTATTAAGTTTAAACAATAAGCAG
TTTGCGACATAATAGTCTCTTACGTCAGCTAATCCATTTATTAATGGAAATTTGTTCGGCTGTTGAAGGT
GATTATTGCTAATGGCCTCAACTGATTTATTCATTGAAGGCAATACCA
Protein Sequence 
>gi|16766173|ref|NP_461788.1| transcriptional regulator SirC [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] MVLPSMNKSVEAISNNHLQQPNKFPLINGLADVRDYYVANCLLFKLNKGSLRIENEFGEFIERSAPCLFLLEKDQTITLSMSEIEGHIDFSSLEVSYDLMQKFYKVFYSTRNYNDRELSLKTKPKYFFHADLLPGMSDTFDSILHGVACPRVCSNVSIDDHDYSYFSLMYLISAFVRKPGGFDFLERAIKITTKEKVYNIIISDLTRKWSQAEVAGKLFMSVSSLKRKLAAEEVSFSKIYLDARMNQAIKLLRMGAGNISQVATMCGYDTPSYFIAIFKRHFKITPLSFMRTMNH
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: hilC mutants have decreased invasion of HEp-2 cells compared to the wild type (Schechter et al., 1999).
COG COG2207K, under K: Transcription
References
Schechter et al., 1999: Schechter LM, Damrauer SM, Lee CA. Two AraC/XylS family members can independently counteract the effect of repressing sequences upstream of the hilA promoter. Molecular microbiology. 1999; 32(3); 629-642. [PubMed: 10320584].