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yeiA

Victor ID 2723
Gene Name yeiA
Sequence Strain (Species/Organism) Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
NCBI Gene ID 1253709
NCBI Protein GI 16765517
Locus Tag STM2187
Protein Accession NP_461132.1
Other Database IDs UniProtKB-ID: Q8ZNL7_SALTY
UniRef100: UniRef100_B5EYN7
UniRef90: UniRef90_P25889
UniRef50: UniRef50_P25889
UniParc: UPI00000CD1C4
EMBL: AE006468
EMBL-CDS: AAL21091.1
RefSeq_NT: NC_003197.1
HSSP: Q28943
GenomeReviews: AE006468_GR
KEGG: stm:STM2187
HOGENOM: HBG472415
OMA: MVTRWCK
ProtClustDB: PRK08318
BioCyc: STYP99287:STM2187-MONOMER
Taxonomy ID 99287
Gene Starting Position 2282627
Gene Ending Position 2283862
Gene Strand (Orientation) +
Protein Name dihydropyrimidine dehydrogenase
DNA Sequence 
>gi|16763390:2282627-2283862 Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 chromosome, complete genome
CATGTTAACAAAAGATTTGTCTGTTACCTTTTGCGGCGTTAAGTTTCCCAATCCGTTTTGTCTTTCTTCT
TCTCCGGTAGGCAATTGTTATGAGATGTGCGCCAAAGCCTATGATACCGGCTGGGGCGGGATCGTTTTTA
AAACCATTGGTTTTTTTATTGCCAACGAAGTCTCTCCACGTTTTGATCACCTGACGAAAGAAGATACCGG
TTTTATTGGCTTCAAAAACATGGAGCAAATTGCTGAGCATCCGCTGGAAGAGAATCTGGCCGCCATTCGA
CGGCTAAAACAGGATTATCCGGATAAGGTGCTGATTGCTTCCATCATGGGAGAAAATGAACAGCAGTGGC
AGGAACTGGCGCGTCTGGTTGAAGAAGCCGGCGCGGATATGATTGAGTGTAACTTCTCTTGCCCGCAGAT
GACCTCGCACGCCATGGGAAGCGATGTAGGGCAAAGCCCGGAACTGGTTGAAAAATACTGCCGCGCCGTA
AAACGCGGTTCATCTTTGCCAATGCTGGCGAAAATGACGCCGAATATTGGCGATATGTGCGAAGTCGCGC
TGGCCGCCAAACGCGGCGGAGCCGACGGTATCGCCACCATCAACACCGTGAAATCCATTACTAACATCGA
CCTGAACCGCAAAATCGGGATGCCGGTGGTTAACGGTAAATCCAGTATCTCCGGTTATTCAGGAAAAGCG
GTGAAACCCATTGCGCTGCGTTTTATCCAGCAGTTGCGAATGCACCCTGAACTGCGCGATTTCCCGATTA
GCGGTATCGGCGGCATTGAAACCTGGGAAGACGCTGCCGAATTTCTGCTGCTGGGCGCGGCGACCCTACA
GGTGACGACAGGCATTATGCAATACGGTTATCGCATTGTAGAAGATATGGCGAGCGGCCTCAGCCACTAT
CTGGCCGATCAGGGATTTGCCTCATTACAGGAGATGATCGGGCTGGCGAATGGCAATATTATCCCGGCGG
AAGACCTGGATCGCAGCTATATCGTCTATCCGCGGATTAATCAGGAGAAATGCGTCGGCTGCGGACGTTG
CTATATCTCCTGCTATGACGGCGGTCATCAGGCGATGGAGTGGGATGAACACAGCCGCACGCCGCATTGC
AATACGGAAAAATGCGTCGGTTGTCTGCTGTGCGGTCATGTCTGCCCGGTCGCCTGTATTGATTTAGGCG
AGGTCAAATTTAAAAAAGGCGAAAAAGAGCACGCGTTAACACTGTA
Protein Sequence 
>gi|16765517|ref|NP_461132.1| NAD-dependent dihydropyrimidine dehydrogenase subunit PreA [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] MLTKDLSVTFCGVKFPNPFCLSSSPVGNCYEMCAKAYDTGWGGIVFKTIGFFIANEVSPRFDHLTKEDTGFIGFKNMEQIAEHPLEENLAAIRRLKQDYPDKVLIASIMGENEQQWQELARLVEEAGADMIECNFSCPQMTSHAMGSDVGQSPELVEKYCRAVKRGSSLPMLAKMTPNIGDMCEVALAAKRGGADGIATINTVKSITNIDLNRKIGMPVVNGKSSISGYSGKAVKPIALRFIQQLRMHPELRDFPISGIGGIETWEDAAEFLLLGAATLQVTTGIMQYGYRIVEDMASGLSHYLADQGFASLQEMIGLANGNIIPAEDLDRSYIVYPRINQEKCVGCGRCYISCYDGGHQAMEWDEHSRTPHCNTEKCVGCLLCGHVCPVACIDLGEVKFKKGEKEHALTL
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: yeiA mutant is attenuated in mice (Lawley et al., 2006).
COG COG0167F, under F: Nucleotide transport and metabolism
References
Lawley et al., 2006: Lawley TD, Chan K, Thompson LJ, Kim CC, Govoni GR, Monack DM. Genome-wide screen for Salmonella genes required for long-term systemic infection of the mouse. PLoS pathogens. 2006; 2(2); e11. [PubMed: 16518469].