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rfbB

Victor ID 2714
Gene Name rfbB
Sequence Strain (Species/Organism) Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
NCBI Gene ID 1253618
NCBI Protein GI 16765427
Locus Tag STM2097
Protein Accession NP_461042.1
Other Database IDs UniProtKB-ID: RMLB_SALTY
UniRef100: UniRef100_P26391
UniRef90: UniRef90_P26391
UniRef50: UniRef50_P26391
UniParc: UPI000011213F
EMBL: X56793
EMBL: AE006468
EMBL-CDS: CAA40115.1
EMBL-CDS: AAL21001.1
RefSeq_NT: NC_003197.1
PDB: 1G1A
PDB: 1KEU
PDB: 1KEW
GenomeReviews: AE006468_GR
KEGG: stm:STM2097
NMPDR: fig|99287.1.peg.2022
HOGENOM: HBG755066
OMA: WSALDGD
ProtClustDB: PRK10084
BioCyc: STYP99287:STM2097-MONOMER
Taxonomy ID 99287
Gene Starting Position 2177494
Gene Ending Position 2178579
Gene Strand (Orientation) -
Protein Name dTDP-glucose 4,6 dehydratase
DNA Sequence 
>gi|16763390:2177494-2178579 Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 chromosome, complete genome
ATTACTGGCGTCCTTCATAGTTCTGTTCTATCCAACTCTGATACGCCCCACTTTTAACATTGTTTACCCA
TTGAGTATTTGCAAGGTACCATTCCACTGTTTTACGAATACCGCTTTCAAAGGTCTCCAGCGGTTTCCAG
CCTAATTCGCGGCTAATTTTACCTGCATCAATGGCATAACGACGATCATGGCCCGGACGATCCGCGACAT
AAGTGATTTGTTCACGATAAGAAGTCGCTTTGGGTACAATCTCATCCAGCAGATCACAGATGGTAAATAC
CACATCGAGATTTTTCTTCTCATTGTGTCCACCAATGTTATAAGTCTCCCCTGCCTTGCCTTCAGTCACT
ACCATATGAAGCGCGCGAGCATGATCTTCTACATATAGCCAATCGCGAATCTGATCCCCTTTGCCATAAA
TTGGCAAAGGCTTTCCTTCCAGTGCGTTCAAAATGACCAACGGAATCAGTTTTTCAGGGAAGTGATAAGG
GCCATAGTTATTAGAACAATTGGTAACGATCGTTGGTAGACCATAGGTACGCCGCCAGGCACGGACTAAA
TGATCGCTGGATGCTTTTGACGCAGAATAGGGGCTACTTGGCGCATATGCCGTCGTTTCAGTAAATAACG
GCAGCGTAACGCTGTTTTCAACTTCATCAGGATGCGGTAAATCGCCGTAAACTTCATCAGTGGAAATATG
ATGAAAACGAAAATTATTTTTTTTATCTTCGCCAAGGGCAGACCAGTATTTACGCGCAACTTCAAGAAGT
GCATAGGTGCCGACGATATTGGTTTCAATAAATGCTGCTGGCCCGGTAATCGAACGGTCCACATGACTTT
CCGCAGCCAAATGCATCACCGCGTCCGGCTGGTACTGCTCAAAAATACGCGTTATTTCAGCGGAATCACA
AATATCCGCGTGTTCAAAATTGTAGCGATTACTTTCAGAAATATCAGAAAGGGATTCAAGATTACCGGCG
TAGGTTAATTTATCAATATTAACTACAGTGTCCTGTGTATTCTTAATAATATGGCGGACAACAGCTGATC
CAATAAAACCTGCCCCGCCAGTAATAAGTATCTTCA
Protein Sequence 
>gi|16765427|ref|NP_461042.1| dTDP-glucose-4,6-dehydratase [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] MKILITGGAGFIGSAVVRHIIKNTQDTVVNIDKLTYAGNLESLSDISESNRYNFEHADICDSAEITRIFEQYQPDAVMHLAAESHVDRSITGPAAFIETNIVGTYALLEVARKYWSALGEDKKNNFRFHHISTDEVYGDLPHPDEVENSVTLPLFTETTAYAPSSPYSASKASSDHLVRAWRRTYGLPTIVTNCSNNYGPYHFPEKLIPLVILNALEGKPLPIYGKGDQIRDWLYVEDHARALHMVVTEGKAGETYNIGGHNEKKNLDVVFTICDLLDEIVPKATSYREQITYVADRPGHDRRYAIDAGKISRELGWKPLETFESGIRKTVEWYLANTQWVNNVKSGAYQSWIEQNYEGRQ
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: rfbB mutant is attenuated in mice (Hensel et al., 1995).
COG COG1088M, under M: Cell wall/membrane/envelope biogenesis
References
Hensel et al., 1995: Hensel M, Shea JE, Gleeson C, Jones MD, Dalton E, Holden DW. Simultaneous identification of bacterial virulence genes by negative selection. Science (New York, N.Y.). 1995; 269(5222); 400-403. [PubMed: 7618105].