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Rv2224c

Victor ID 271
Gene Name Rv2224c
Sequence Strain (Species/Organism) Mycobacterium tuberculosis H37Rv
NCBI Gene ID 887857
NCBI Protein GI 15609361
Locus Tag Rv2224c
Protein Accession NP_216740.1
Other Database IDs UniProtKB-ID: Y2224_MYCTU
UniRef100: UniRef100_P65823
UniRef90: UniRef90_P65823
UniRef50: UniRef50_P65823
UniParc: UPI000013B8C4
EMBL: BX842579
EMBL: AE000516
EMBL-CDS: CAA94647.1
EMBL-CDS: AAK46567.1
RefSeq_NT: NC_000962.2
RefSeq_NT: NC_002755.2
EnsemblGenome: EBMYCG00000002235
EnsemblGenome_TRS: EBMYCT00000002237
EnsemblGenome_PRO: EBMYCP00000002237
EnsemblGenome: EBMYCG00000071120
EnsemblGenome_TRS: EBMYCT00000071125
EnsemblGenome_PRO: EBMYCP00000069184
GenomeReviews: AE000516_GR
GenomeReview
Taxonomy ID 83332
Gene Starting Position 2495460
Gene Ending Position 2497022
Gene Strand (Orientation) -
Protein Name Probable exported protease
DNA Sequence 
>gi|57116681:2495460-2497022 Mycobacterium tuberculosis H37Rv, complete genome
GCTAGCACTTGGCGCCGCTGGGCGGCGTGGTGCCGCCGATTAAATACGCCGTCACGTACTCGTCAATGCA
GCTGTCGCCCTGGAATACCACCGTGTGCTGGGTTCCGTCGAAGGTCAGCAACGAACCGCGAAGCTGGTTC
GCCAGGTCGACCCCGGCCTTGTACGGCGTCGCCGGGTCATGGGTGGTGGATACCACCACCGTCGGCACTA
GGCCGGGCGCCGAGACGGCATGGGGCTGACTTGTGGGTGGCACCGGCCAGAACGCGCAGGTGCCCAGCGG
CGCATCACCGGTGAACTTCCCGTAGCTCATGAACGGTGCGATCTCCCGGGCGCGGCGGTCTTCGTCGATG
ACCTTGTCGCGATCGGTAACCGGGGGCTGATCGACGCAATTGATCGCCACCCGCGCGTCACCGGAATTGT
TGTAGCGGCCGTGCGAGTCCCGACGCATGTACATGTCGGCCAGAGCCAGCAGGGTGTCTCCGCGATTGTC
GACCAGCTCCGACAGCCCGTCGGTCAAGTGTTGCCACAGATTCGGTGAGTACAGCGCCATAATGGTGCCC
ACGATGGCGTCGCTATAACTCAGCCCGCGCGGATCCTTCGTGCGCGCCGGCCTGCTGATCCTCGGGTTGT
CCGGGTCGACCAACGGATCGACCAGGCTGTGGTAGACCTCGACGGCTTTGGCCGGGTCGGCGCCCAGCGG
GCAGCCCGCGTTCTTGGCGCAGTCGGCGGCATAGTTGTTGAACGCGTCCTGGAAGCCCTTGGCCTGGCGC
AGCTCCGCCTCGATGGGATCGGCATTGGGGTCGACGGCACCGTCGAGAATCATTGCCCGCACCCGCTGCG
GAAATTCCTCGGCATACGCGGAGCCGATCCGGGTGCCGTACGAGTAGCCCAGGTAGGTCAGCTTGTCGTC
GCCCAACGCCGCGCGAATGGCATCCAGGTCCTTGGCGACGTTGACCGTCCCGACATGGGCCAGAAAGTTC
TTGCCCATCTTGTCCACACAGCGACCGACGAATTGCTTGGTCTCGTTCTCGATGTGCGCCACACCCTCCC
GGCTGTAGTCAACCTGCGGCTCGGCCCGCAGCCGGTCGTTGTCGGCATCGGAGTTGCACCAGATCGCCGG
CCGGGACGACGCCACCCCGCGGGGGTCGAACCCAACCAGGTCGAACCTTTCGTGCACCCGCTTCGGCAAT
GTCTGGAAGACGCCCAAGGCGGCCTCGATACCGGATTCGCCGGGTCCACCGGGATTTATGACCAGCGAAC
CGATCTTGTCTCCCGTCGCCGGAAAGCGAATCAGCGCCAGCGCCGCCACGTCACCATCGGGGCGGTCGTA
GTCGACCGGTACAGCGAGCTTGCCGCATAACGCGCCGCCGGGGATCTTTACTTGCGGGTTTGACGACCGG
CACGGTGTCCACTCCACCGGCTGGCCCAGCTTCGGCTCCGCCATACGAGCGCGTCCCCCGACCACGCGGA
TGCAGCCCACAAGAACCAACGCCACGGCGGCGAGCGCGGCCCAGATCAACAGCATGCGCGCGATCTTGTC
GCGGCGAGACAGCCTCATGCCCA
Protein Sequence 
>gi|15609361|ref|NP_216740.1| carboxylesterase A [Mycobacterium tuberculosis H37Rv] MGMRLSRRDKIARMLLIWAALAAVALVLVGCIRVVGGRARMAEPKLGQPVEWTPCRSSNPQVKIPGGALCGKLAVPVDYDRPDGDVAALALIRFPATGDKIGSLVINPGGPGESGIEAALGVFQTLPKRVHERFDLVGFDPRGVASSRPAIWCNSDADNDRLRAEPQVDYSREGVAHIENETKQFVGRCVDKMGKNFLAHVGTVNVAKDLDAIRAALGDDKLTYLGYSYGTRIGSAYAEEFPQRVRAMILDGAVDPNADPIEAELRQAKGFQDAFNNYAADCAKNAGCPLGADPAKAVEVYHSLVDPLVDPDNPRISRPARTKDPRGLSYSDAIVGTIMALYSPNLWQHLTDGLSELVDNRGDTLLALADMYMRRDSHGRYNNSGDARVAINCVDQPPVTDRDKVIDEDRRAREIAPFMSYGKFTGDAPLGTCAFWPVPPTSQPHAVSAPGLVPTVVVSTTHDPATPYKAGVDLANQLRGSLLTFDGTQHTVVFQGDSCIDEYVTAYLIGGTTPPSGAKC
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: attenuated in mice (Sassetti and Rubin, 2003).
COG COG0596R, under R: General function prediction only
References
Sassetti and Rubin, 2003: Sassetti CM, Rubin EJ. Genetic requirements for mycobacterial survival during infection. Proceedings of the National Academy of Sciences of the United States of America. 2003; 100(22); 12989-12994. [PubMed: 14569030].