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udg

Victor ID 2704
Gene Name udg
Sequence Strain (Species/Organism) Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
NCBI Gene ID 1253601
NCBI Protein GI 16765410
Locus Tag STM2080
Protein Accession NP_461025.1
Other Database IDs UniProtKB-ID: UDG_SALTY
UniRef100: UniRef100_Q04873
UniRef90: UniRef90_Q04873
UniRef50: UniRef50_O33952
UniParc: UPI0000137AAA
EMBL: Z17278
EMBL: AE006468
EMBL-CDS: CAA78945.1
EMBL-CDS: AAL20984.1
RefSeq_NT: NC_003197.1
GenomeReviews: AE006468_GR
KEGG: stm:STM2080
NMPDR: fig|99287.1.peg.2005
HOGENOM: HBG400967
OMA: LNFRATT
ProtClustDB: CLSK880271
BioCyc: STYP99287:STM2080-MONOMER
Taxonomy ID 99287
Gene Starting Position 2157957
Gene Ending Position 2159123
Gene Strand (Orientation) -
Protein Name UDP-glucose/GDP-mannose dehydrogenase
DNA Sequence 
>gi|16763390:2157957-2159123 Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 chromosome, complete genome
ATTAATCACTACCGAAAAGATCGCGGGTATACACTTTTTCAGCGACATCCAAAAGCTCTGCCGCCATCCT
GTTGGAAATAATGACATCCGCCTGCTGTTTAAAGCAGTGCAAATCACGTTCAAGACGTGAGTTAAAGAAA
GTATCTTCTTCCATTACCGGCTCATAGATGATGACCTCTACGCCTTTCGCTTTAATGCGCTTCATAATCC
CCTGAATCGATGAGGCGCGGAAGTTATCGGAGCCACTCTTCATAATCAGGCGATAAATGCCCACCACTTT
AGGCTTTCTGGCGAGGATAGCGTCGGCAATAAAATCTTTACGCGTACGGTTTGCTTCAACGATAGCGGAG
ATAATATTATTAGGCACCGACTGATAATTGGCCAGCAACTGTTTGGTATCTTTTGGCAAACAATATCCGC
CATAACCAAAAGAGGGATTATTATAATGATTGCCAATACGCGGGTCGAGGCACACCCCTTCAATAATTTG
TCGGGTATTTAATCCTAACGTTTCAGCATAGCTGTCTAATTCATTAAAATAAGCGACTCGCATAGCGAGA
TAAGTATTGGCGAAAAGTTTAATGGCTTCCGCCTCAGTGGAGTCCGTAAACAGCGTTGGAATCTCCTGTT
TAATAGCGCCTTCCTGGAGTAATGCGGCAAATTCTCTGGCGCGCTCAGACTGTTCCCCAATCACGATACG
GGAGGGATAAAGGTTATCGTAAAGGGCTTTACCTTCACGTAAAAACTCCGGAGAGAAAATGATATTTTCT
GTCGCAAACTTCTGACGCATTGCCGCCGTGAAGCCAACCGGCACCGTAGACTTAATAATCATCACTGCTG
CGGGGTTGATGCTGATCACATCCTGCATGACCGATTCCACACTGGACGTATTAAAATAGTTAGTTTTGGG
ATCGTAATCCGTAGGCGTAGCAATGATGACGTAATCTGCATTCTGGTACGCATCAAACTTATCCAGCGTT
GCCCTGAATCTGATGTTATCTTCCTTTAAAAATTGCTGAATTTCTTTATCAACAATCGGAGATATCCGAT
CATTTAACAGTTCAACACGGGAAGGAACAATGTCTAACGCCACCACATCATGATGTTGTGCAATAAGCAA
ACCATTAGACAAGCCAACATAACCCGTCCCGGATATCGTGATTTTCA
Protein Sequence 
>gi|16765410|ref|NP_461025.1| UDP-glucose 6-dehydrogenase [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] MKITISGTGYVGLSNGLLIAQHHDVVALDIVPSRVELLNDRISPIVDKEIQQFLKEDNIRFRATLDKFDAYQNADYVIIATPTDYDPKTNYFNTSSVESVMQDVISINPAAVMIIKSTVPVGFTAAMRQKFATENIIFSPEFLREGKALYDNLYPSRIVIGEQSERAREFAALLQEGAIKQEIPTLFTDSTEAEAIKLFANTYLAMRVAYFNELDSYAETLGLNTRQIIEGVCLDPRIGNHYNNPSFGYGGYCLPKDTKQLLANYQSVPNNIISAIVEANRTRKDFIADAILARKPKVVGIYRLIMKSGSDNFRASSIQGIMKRIKAKGVEVIIYEPVMEEDTFFNSRLERDLHCFKQQADVIISNRMAAELLDVAEKVYTRDLFGSD
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: udg mutant is attenuated in mice (Lawley et al., 2006).
COG COG1004M, under M: Cell wall/membrane/envelope biogenesis
References
Lawley et al., 2006: Lawley TD, Chan K, Thompson LJ, Kim CC, Govoni GR, Monack DM. Genome-wide screen for Salmonella genes required for long-term systemic infection of the mouse. PLoS pathogens. 2006; 2(2); e11. [PubMed: 16518469].