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uvrY

Victor ID 2699
Gene Name uvrY
Sequence Strain (Species/Organism) Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
NCBI Gene ID 1253468
NCBI Protein GI 16765285
Locus Tag STM1947
Protein Accession NP_460900.1
Other Database IDs UniProtKB-ID: Q79BM8_SALTY
UniRef100: UniRef100_B4T843
UniRef90: UniRef90_P0AED5
UniRef50: UniRef50_Q52376
UniParc: UPI0000059CC6
EMBL: U88651
EMBL: U67869
EMBL: AE006468
EMBL-CDS: AAC08300.1
EMBL-CDS: AAC44801.1
EMBL-CDS: AAL20859.1
RefSeq_NT: NC_003197.1
GenomeReviews: AE006468_GR
KEGG: stm:STM1947
HOGENOM: HBG753323
OMA: TKGAAPD
ProtClustDB: PRK09483
BioCyc: STYP99287:STM1947-MONOMER
Taxonomy ID 99287
Gene Starting Position 2038246
Gene Ending Position 2038902
Gene Strand (Orientation) -
Protein Name response regulator
DNA Sequence 
>gi|16763390:2038246-2038902 Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 chromosome, complete genome
CTCACTGGCTTGTTAACGTCTCCGCATTACACAGGCCATGGCGGATTGCCAGGTGAGTCAGCTCAACATC
ACCATGAATGTTTAATTTACTGAACATACGATAGCGATAGCTGTTCACCGTTTTAGGACTGAGATTCAGC
TGTTCTGAAATCTCATTGACCTTCTGACCCTTGGTGATCATCAGCATAATCTGCAACTCGCGTTCAGACA
AACTGGCGAACGGCGTTTCCGTTTTTGCAGGCTCAATCTGACTGAGCGCCATCTGCTGAGCGATATCGGA
GGCGATATAACGTTGTCCGGAATACACCGAACGAATAGCGCTCACCACCTCCTGAGGCGCAGCGCCTTTG
CTGAGATAGCCAGCTGCGCCAGCCTGCATCACTTTGGCGGGCAACGGGTTCTCCGTATGGACGGTCAGCA
TGATCACTTTGATATCCGCTGTCGAGCGGGCAATTTTACGCGTCGCCTCAAGGCCGCCAATACCGGGCAT
GTTCATATCCATCAGCACGACGTCAACGGCGTTAGTACGGCACCATTTTACCGCATCCTCTCCGCAGCAC
GCTTCACCGACAACTTTAATGCCCTTTATATCTTCAAGAATGCGTCGTATCCCTGCGCGCACCAGTTCGT
GGTCATCAACAAGAAGAACGTTGATCA
Protein Sequence 
>gi|16765285|ref|NP_460900.1| LuxR/UhpA family response regulator [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] MINVLLVDDHELVRAGIRRILEDIKGIKVVGEACCGEDAVKWCRTNAVDVVLMDMNMPGIGGLEATRKIARSTADIKVIMLTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPAKTETPFASLSERELQIMLMITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLTSQ
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: sirA mutant is defective for intracellular replication, invasion of epithelial cells and defective in murine macrophages (Chan et al., 2005).
COG COG2197TK, under T: Signal transduction mechanisms; K: Transcription
References
Chan et al., 2005: Chan K, Kim CC, Falkow S. Microarray-based detection of Salmonella enterica serovar Typhimurium transposon mutants that cannot survive in macrophages and mice. Infection and immunity. 2005; 73(9); 5438-5449. [PubMed: 16113260].