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znuA

Victor ID 2694
Gene Name znuA
Sequence Strain (Species/Organism) Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
NCBI Gene ID 1253412
NCBI Protein GI 161353595
Locus Tag STM1891
Protein Accession NP_460848.2
Taxonomy ID 99287
Gene Starting Position 1986414
Gene Ending Position 1987358
Gene Strand (Orientation) -
Protein Name high-affinity zinc transporter periplasmic component
DNA Sequence 
>gi|16763390:1986414-1987358 Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 chromosome, complete genome
GTTAATCTCCTTTCAGGCAGCTCGCATACTGGTTGGCTAATTGGCTTAAAAACGCTGAATAGCTTGTTTT
ACCCAGTTTAATGTTCGTCCCGAGGGGGTCCAGTGTTCCCATTCGAACGGATGTCCCTCTCGCCACGGCT
TCCACGACCGCTGGCCTGAATTGTGGCTCAGCAAAAACGCAGGTTGCTTTTTGCTCAACCAACTGTGTTC
TTATTTCATGTAAACGCTGCGCGCCAGGTTGTATCTCAGGGTTCACGGTAAAGTGACCGAGCGGGGTGAG
TCCGTAGTGTTTTTCGTAGTAACCGTAGGCGTCATGAAAAACGAAATACCCTTTCCCCTTGAGCGGCGCG
AGCTCGTTACCGACCTGTTTATCGGTTGCGGCTAATTGTGCCTCAAAATCCTTCAGGTTGGCGTCGAGTT
TGGCTCGACTTTGCGGCATAAGTTCCACTAATTTTTCATGGATTGCAACCGCTGTAGCCCGCGCTATCTC
TGGGGAGAGCCAAAGATGCATGTTATATTCGCCGTGATGGTGATGTACGTCACCTTTTTCCTCATCGGCG
CCCGTATGCGCATGTTCATCCTCATCATCATCCGCGCCCTTCATGAGTAACGGTTTTACATCGGCAAGTT
GCGCAATGGTAACCTGCTTATTATCAGGGATATTCCTGACCGACTTCTCCATAAAGGCTTCCATTTCCGG
GCCAACCCAGACGACTAAGTCCGCGCCCTGTAAGCGTTTTACGTCTGATGGACGCAATGAATAATCATGC
TCGGAAGCCCCATCCGGAAGTAATACTTGCGTATCCGTAACGCCATCAGCAATGGCGGAAGCGATGAACC
CAAGCGGTTTAAGCGAAGCGACAACGGCGGCGTCGGCAGCCTGGGTTGCACTCCCCCAAAGCGCGGCGGA
TAATGCTGCGAAAAGAAGCGTATTTTTCTGTAACA
Protein Sequence 
>gi|161353595|ref|NP_460848.2| zinc ABC transporter substrate-binding protein ZnuA [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] MLQKNTLLFAALSAALWGSATQAADAAVVASLKPLGFIASAIADGVTDTQVLLPDGASEHDYSLRPSDVKRLQGADLVVWVGPEMEAFMEKSVRNIPDNKQVTIAQLADVKPLLMKGADDDEDEHAHTGADEEKGDVHHHHGEYNMHLWLSPEIARATAVAIHEKLVELMPQSRAKLDANLKDFEAQLAATDKQVGNELAPLKGKGYFVFHDAYGYYEKHYGLTPLGHFTVNPEIQPGAQRLHEIRTQLVEQKATCVFAEPQFRPAVVEAVARGTSVRMGTLDPLGTNIKLGKTSYSAFLSQLANQYASCLKGD
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: znuABC mutant is attenuated in mice (Pesciaroli et al., 2011).
COG COG4531P, under P: Inorganic ion transport and metabolism
References
Pesciaroli et al., 2011: Pesciaroli M, Aloisio F, Ammendola S, Pistoia C, Petrucci P, Tarantino M, Francia M, Battistoni A, Pasquali P. An attenuated Salmonella enterica serovar Typhimurium strain lacking the ZnuABC transporter induces protection in a mouse intestinal model of Salmonella infection. Vaccine. 2011; ; . [PubMed: 21219981].