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Rv3588c

Victor ID 269
Gene Name Rv3588c
Sequence Strain (Species/Organism) Mycobacterium tuberculosis H37Rv
NCBI Gene ID 887836
NCBI Protein GI 15610724
Locus Tag Rv3588c
Protein Accession NP_218105.1
Other Database IDs UniProtKB-ID: CYNT_MYCTU
UniRef100: UniRef100_O53573
UniRef90: UniRef90_O53573
UniRef50: UniRef50_O53573
UniParc: UPI00000D5EF6
EMBL: BX842583
EMBL: AE000516
EMBL-CDS: CAA17857.1
EMBL-CDS: AAK48052.1
RefSeq_NT: NC_000962.2
RefSeq_NT: NC_002755.2
PDB: 1YM3
PDB: 2A5V
EnsemblGenome: EBMYCG00000003861
EnsemblGenome_TRS: EBMYCT00000003863
EnsemblGenome_PRO: EBMYCP00000003863
EnsemblGenome: EBMYCG00000072644
EnsemblGenome_TRS: EBMYCT00000072649
EnsemblGenome_PRO: EBMYCP00000070708
GenomeReviews: AE000
Taxonomy ID 83332
Gene Starting Position 4029870
Gene Ending Position 4030493
Gene Strand (Orientation) -
Protein Name CARBONIC ANHYDRASE (CARBONATE DEHYDRATASE) (CARBONIC DEHYDRATASE)
DNA Sequence 
>gi|57116681:4029870-4030493 Mycobacterium tuberculosis H37Rv, complete genome
CTCAGACCTCCTCGCCGATGTTGCCGATGTGGTCGCGCAGTACAGCCCGCCCATCGTCGAGTTGATAGGT
GACGCCCACGATCGCCAGGCTGCCCCCTGCGATTCGTTCTGAGATGGCCGATGAACGCGCCATGAGGATC
GCCACCGTCTCGTGTACATGTCGTTGCTCGAACTCGTCGACACGACTCAGACCGTCACGGCGGCCGAGCA
GGACCGACGGCGCAACCCTTTCCACGACGTCTCGCACGTAGCCGCCTGGCAGGGTGCCGTCGTTGATCGC
GGCCAAAGCGGCGTTCACGGCGCCGCAGCTGTCGTGGCCGAGGACGACGATGAGCGGCACATTGAGCACG
GTCACCGCGTACTCTATGGAGCCCAGCACGGCCGAGTCGATGACATGCCCGGCGGTGCGGACCACGAACA
TGTCGCCCAGGCCTTGGTCGAAGATGATCTCAGCGGCCACTCGGCTGTCCGCGCAGCCGAAGATCACCGC
CGTGGGCTTCTGCCCGGCGGCCAAGCCGGCTCGGTGGTCGACGCTCTGACTGGGATGCTGGGGCCGGCCG
GCGACGAATCGCTCGTTACCCTCTTTGAGTGCTTTCCACGCGGCTACCGGATTGGTGTTGGGCA
Protein Sequence 
>gi|15610724|ref|NP_218105.1| carbonic anhydrase [Mycobacterium tuberculosis H37Rv] MPNTNPVAAWKALKEGNERFVAGRPQHPSQSVDHRAGLAAGQKPTAVIFGCADSRVAAEIIFDQGLGDMFVVRTAGHVIDSAVLGSIEYAVTVLNVPLIVVLGHDSCGAVNAALAAINDGTLPGGYVRDVVERVAPSVLLGRRDGLSRVDEFEQRHVHETVAILMARSSAISERIAGGSLAIVGVTYQLDDGRAVLRDHIGNIGEEV
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: attenuated in mice (Sassetti and Rubin, 2003).
COG COG0288P, under P: Inorganic ion transport and metabolism
References
Sassetti and Rubin, 2003: Sassetti CM, Rubin EJ. Genetic requirements for mycobacterial survival during infection. Proceedings of the National Academy of Sciences of the United States of America. 2003; 100(22); 12989-12994. [PubMed: 14569030].