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sseC from Salmonella enterica subsp. enterica serovar Typhimurium str. LT2

Victor ID 2659
Gene Name sseC from Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
Sequence Strain (Species/Organism) Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
NCBI Gene ID 1252918
NCBI Protein GI 16764750
Locus Tag STM1400
Protein Accession NP_460365.1
Other Database IDs UniProtKB-ID: SSEC_SALTY
UniRef100: UniRef100_O84947
UniRef90: UniRef90_O84947
UniRef50: UniRef50_O84947
UniParc: UPI00000D0102
EMBL: AJ224892
EMBL: AF020808
EMBL: AE006468
EMBL: DQ320510
EMBL-CDS: CAA12187.1
EMBL-CDS: AAC28881.1
EMBL-CDS: AAL20324.1
EMBL-CDS: ABC59204.1
RefSeq_NT: NC_003197.1
TCDB: 1.C.36.5.1
GenomeReviews: AE006468_GR
KEGG: stm:STM1400
NMPDR: fig|99287.1.peg.1356
HOGENOM: HBG679868
OMA: QARIAGC
ProtClustDB: CLSK894170
BioCyc: STYP99287:STM1400-MONOMER
Taxonomy ID 99287
Gene Starting Position 1484996
Gene Ending Position 1486450
Gene Strand (Orientation) +
Protein Name translocation machinery component
DNA Sequence 
>gi|16763390:1484996-1486450 Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 chromosome, complete genome
AATGAATCGAATTCACAGTAATAGCGACAGCGCCGCAGGAGTAACCGCCTTAACACATCATCACTTAAGC
AATGTCAGTTGCGTTTCCTCGGGTTCGCTGGGAAAGCGCCAGCATCGTGTGAATTCTACTTTTGGCGATG
GCAACGCCGCGTGTCTGCTATCCGGGAAAATTAGTCTTCAGGAGGCAAGCAATGCGTTGAAGCAACTGCT
TGATGCCGTACCCGGAAATCATAAGCGTCCATCATTGCCTGACTTTTTGCAGACCAATCCCGCGGTTTTA
TCAATGATGATGACGTCATTAATACTCAACGTCTTTGGTAATAACGCTCAATCGTTATGCCAACAGCTTG
AGCGGGCAACTGAGGTGCAAAATGCATTACGTAATAAGCAGGTAAAGGAGTATCAGGAGCAGATCCAGAA
AGCGATAGAGCAGGAGGATAAAGCGCGTAAAGCGGGTATTTTTGGCGCTATTTTTGACTGGATTACCGGC
ATATTTGAAACCGTGATTGGCGCCTTAAAAGTTGTGGAAGGTTTTCTGTCCGGAAATCCCGCAGAAATGG
CTAGCGGCGTAGCTTATATGGCCGCAGGTTGTGCAGGAATGGTTAAAGCCGGAGCCGAAACGGCAATGAT
GTGCGGTGCTGACCACGATACCTGTCAGGCAATTATTGACGTGACAAGTAAGATTCAATTTGGTTGTGAA
GCCGTCGCGCTGGCACTGGATGTTTTCCAGATTGGCCGTGCTTTTATGGCGACGAGAGGTTTATCTGGCG
CAGCTGCAAAAGTGCTTGACTCCGGTTTTGGCGAGGAAGTGGTTGAGCGTATGGTAGGTGCAGGGGAAGC
AGAAATAGAGGAGTTGGCTGAAAAGTTTGGCGAAGAAGTGAGCGAAAGTTTTTCCAAACAATTTGAGCCG
CTTGAACGTGAAATGGCTATGGCGAATGAGATGGCAGAGGAGGCTGCCGAGTTTTCTCGTAACGTAGAAA
ATAATATGACGCGAAGCGCGGGAAAAAGCTTTACGAAAGAGGGGGTGAAAGCCATGGCAAAAGAAGCGGC
AAAAGAAGCCCTGGAAAAATGTGTGCAAGAAGGTGGAAAGTTCCTGTTAAAAAAATTCCGTAATAAAGTT
CTCTTCAATATGTTCAAAAAAATCCTGTATGCCTTACTGAGGGATTGTTCATTTAAAGGCTTACAGGCTA
TCAGATGTGCAACCGAGGGCGCCAGTCAGATGAATACTGGCATGGTTAACACAGAAAAAGCGAAGATCGA
AAAGAAAATAGAGCAATTAATAACTCAGCAACGGTTTCTGGATTTCATAATGCAACAAACAGAAAACCAG
AAAAAGATAGAACAAAAACGCTTAGAGGAGCTTTATAAGGGGAGCGGTGCCGCGCTTAGAGATGTATTAG
ATACCATTGATCACTATAGTAGCGTTCAGGCGAGAATAGCTGGCTATCGCGCTTA
Protein Sequence 
>gi|16764750|ref|NP_460365.1| secreted effector protein SseC [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] MNRIHSNSDSAAGVTALTHHHLSNVSCVSSGSLGKRQHRVNSTFGDGNAACLLSGKISLQEASNALKQLLDAVPGNHKRPSLPDFLQTNPAVLSMMMTSLILNVFGNNAQSLCQQLERATEVQNALRNKQVKEYQEQIQKAIEQEDKARKAGIFGAIFDWITGIFETVIGALKVVEGFLSGNPAEMASGVAYMAAGCAGMVKAGAETAMMCGADHDTCQAIIDVTSKIQFGCEAVALALDVFQIGRAFMATRGLSGAAAKVLDSGFGEEVVERMVGAGEAEIEELAEKFGEEVSESFSKQFEPLEREMAMANEMAEEAAEFSRNVENNMTRSAGKSFTKEGVKAMAKEAAKEALEKCVQEGGKFLLKKFRNKVLFNMFKKILYALLRDCSFKGLQAIRCATEGASQMNTGMVNTEKAKIEKKIEQLITQQRFLDFIMQQTENQKKIEQKRLEELYKGSGAALRDVLDTIDHYSSVQARIAGYRA
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: sseC mutant is attenuated in mice (Klein and Jones, 2001).
COG COG5613S, under S: Function unknown
References
Klein and Jones, 2001: Klein JR, Jones BD. Salmonella pathogenicity island 2-encoded proteins SseC and SseD are essential for virulence and are substrates of the type III secretion system. Infection and immunity. 2001; 69(2); 737-743. [PubMed: 11159962].