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csgD

Victor ID 2640
Gene Name csgD
Sequence Strain (Species/Organism) Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
NCBI Gene ID 1252660
NCBI Protein GI 16764498
Locus Tag STM1142
Protein Accession NP_460113.1
Other Database IDs UniProtKB-ID: CSGD_SALTY
UniRef100: UniRef100_O54294
UniRef90: UniRef90_P52106
UniRef50: UniRef50_P52106
UniParc: UPI0000128530
EMBL: AJ002301
EMBL: AE006468
EMBL-CDS: CAA05315.1
EMBL-CDS: AAL20072.1
RefSeq_NT: NC_003197.1
GenomeReviews: AE006468_GR
KEGG: stm:STM1142
HOGENOM: HBG303489
OMA: INGVNDD
ProtClustDB: PRK10100
BioCyc: STYP99287:STM1142-MONOMER
Taxonomy ID 99287
Gene Starting Position 1229727
Gene Ending Position 1230377
Gene Strand (Orientation) -
Protein Name DNA-binding transcriptional activator in two-component regulatory system
DNA Sequence 
>gi|16763390:1229727-1230377 Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 chromosome, complete genome
CTTACCGCCTGAGATTATCGTTTGCCCATGAAACTGCCTGGGTGCGATTTTTGACAGCTATCTTTTTGAA
AAGATTATAAAGATGTGTCTTAACCGTATTCTCGCTGATAAATAGCGACCTCGCGATTTCATTATTAGAG
GCACCAATACGTAACTTATTGAGGATCTCTTTTTCGCGATGAGTGAGTAATGCGGACTCGGTGCTGTTGT
AGCGGTAATTTCCTGAGTGCGTAATCAGGTAACTGGCTAATTTTTGTGAAAAATAGCATTCGCCACGCAG
AATACCCTGTAATCCGCTGACCACGTGTTCCTGGTCTTCAGTAGCGTAAAACACGCCGTTAATATGAGGC
CAGTTTTCAATTTCACGGTAGGGATAATCGTCAGGGGTATTTAACAATAATGTTTTTATATTATTGTTTT
TGCGGCTTAAATTATCCTGCCAATAGTGGATAAGCTTCTTATCCGCTTCCATCATATCCATTAAAACAAT
GCAACCGGCCGAGATATCTTCCAGAGAACGTTGAATATTATGCAGTTTTCCGGTTATGGCCAGCGATTGC
TTTAAATGTTGCAATAATGCCGTAGCTTGCAGAGATGGCTTTGTGATCAACAATAGTGTGTGACCATGAC
TACTATGGACTTCATTAAACA
Protein Sequence 
>gi|16764498|ref|NP_460113.1| DNA-binding transcriptional regulator CsgD [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] MFNEVHSSHGHTLLLITKPSLQATALLQHLKQSLAITGKLHNIQRSLEDISAGCIVLMDMMEADKKLIHYWQDNLSRKNNNIKTLLLNTPDDYPYREIENWPHINGVFYATEDQEHVVSGLQGILRGECYFSQKLASYLITHSGNYRYNSTESALLTHREKEILNKLRIGASNNEIARSLFISENTVKTHLYNLFKKIAVKNRTQAVSWANDNLRR
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: csgD mutant is attenuated in mice (Lawley et al., 2006).
COG COG2197TK, under T: Signal transduction mechanisms; K: Transcription
References
Lawley et al., 2006: Lawley TD, Chan K, Thompson LJ, Kim CC, Govoni GR, Monack DM. Genome-wide screen for Salmonella genes required for long-term systemic infection of the mouse. PLoS pathogens. 2006; 2(2); e11. [PubMed: 16518469].