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mce2A from Mycobacterium tuberculosis H37Rv

Victor ID 264
Gene Name mce2A from Mycobacterium tuberculosis H37Rv
Sequence Strain (Species/Organism) Mycobacterium tuberculosis H37Rv
NCBI Gene ID 887745
NCBI Protein GI 57116756
Locus Tag Rv0589
Protein Accession YP_177740.1
Other Database IDs UniProtKB-ID: Q79FY7_MYCTU
UniRef100: UniRef100_A5TZW9
UniRef90: UniRef90_A5WJV4
UniRef50: UniRef50_A5TYP4
UniParc: UPI00000CCB3D
EMBL: BX842574
EMBL-CDS: CAE55301.1
RefSeq_NT: NC_000962.2
EnsemblGenome: EBMYCG00000002768.
EnsemblGenome_TRS: EBMYCT00000002770
EnsemblGenome_PRO: EBMYCP00000002770
GenomeReviews: AL123456_GR
KEGG: mtu:Rv0589
TubercuList: Rv0589
HOGENOM: HBG659494
OMA: VEPKIAD
ProtClustDB: CLSK799409
Taxonomy ID 83332
Gene Starting Position 686820
Gene Ending Position 688034
Gene Strand (Orientation) +
Protein Name MCE-FAMILY PROTEIN MCE2A
DNA Sequence 
>gi|57116681:686820-688034 Mycobacterium tuberculosis H37Rv, complete genome
GGTGCCAACGCTGGTGACGAGGAAGAACCGACGTGCGTGGCTGTATGTGGAGGGTGTTGTCCTGCTGTTG
GTGGGCGCGTTGGTGCTCGTATTGGTGTACAAGCAGTTTCGTGGGGAATTCACGCCGAAGACCGAGCTGA
CTATGGTCGCCTTCCGGGCTGGGCTGGTTATGGAAGCTGGATCCAAAGTCACCTACAACGGGGTGGAGAT
CGGCCGGGTGGGCAGCATTTCGGAGATTGAGCGTGACGGCCGGCCGGCGGCGAAGCTGGTTTTGGACGTG
AATCCTCGCTACATCAGCCTGATTCCGGTCAATGTGGTGGCCGATATCGAGGCGGCCACCCTGTTCGGCA
ACAAGTATGTTGCGCTGTCCGCGCCGAAAATTCCTCAACAGCAGCGGATTTCCTCACATGACGTGATTGA
TGTGGGGTCGGTGACCACCGAATTCAACACGTTGTTCGAGACGATCACCTCGATCGCCGAGAAGGTGGAT
CCGATCGAGCTGAACGCGACGCTGTCCGCGGTAGCACAGGCGCTGGATGGGCTGGGCGGCAAGTTCGGTG
AGTCGATCGTTAATGGCAATCAGATTCTGGCGCAATTAAATCCGCGGCTGCCGCAGCTCGGCTATGATGT
TCGGCGGTTGGCGGATCTCGGTGAGGTCTATGTCGATGCTTCGCCGGATCTGTGGTCCTTTCTGCAGAAC
GCACTGACCACTGCGCGCACATTGACCAGCCAACAGCGCGATCTGGATGCCGCGTTGTTGGCGGCTACGG
GTGCGGGCAACACCGGTGAAGACGTTTTTGCTCGAGGCGGGCCGTATCTTGCGCGCGCAGCCGCCGATCT
GGTGCCCACCGCTACGCTGCTGGACACCTACAGTCCCGAACTGTTCTGCATGATCCGCAACTTTCACGAC
GCTGCGCCCAAAGTCGCGGACGCGGTGGGCGGCAACGGCTATTCGCTAGCGGCCGCCGGAACGATTTTGG
GAGCACCCAATCCCTATGTCTATCCGGACAATCTGCCGCGGGTGAATGCCCACGGTGGACCCGGGGGCCG
ACCGGGCTGCTGGCAGACGATCACCCGGGAGCTGTGGCCGGCACCCTATCTGGTGATGGACACCGGTGCC
AGCCTCGCACCGTACAACCACGTCGAGCTCGGCCAACCGATGTTCACTGAATACGTATGGGGACGCCAAT
ACGGAGAGAACACGATCAACCCATG
Protein Sequence 
>gi|57116756|ref|YP_177740.1| Mce family protein Mce2A [Mycobacterium tuberculosis H37Rv] MPTLVTRKNRRAWLYVEGVVLLLVGALVLVLVYKQFRGEFTPKTELTMVAFRAGLVMEAGSKVTYNGVEIGRVGSISEIERDGRPAAKLVLDVNPRYISLIPVNVVADIEAATLFGNKYVALSAPKIPQQQRISSHDVIDVGSVTTEFNTLFETITSIAEKVDPIELNATLSAVAQALDGLGGKFGESIVNGNQILAQLNPRLPQLGYDVRRLADLGEVYVDASPDLWSFLQNALTTARTLTSQQRDLDAALLAATGAGNTGEDVFARGGPYLARAAADLVPTATLLDTYSPELFCMIRNFHDAAPKVADAVGGNGYSLAAAGTILGAPNPYVYPDNLPRVNAHGGPGGRPGCWQTITRELWPAPYLVMDTGASLAPYNHVELGQPMFTEYVWGRQYGENTINP
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: mce2A mutant is attenuated in mice (Gioffré et al., 2005).
COG COG1463Q, under Q: Secondary metabolites biosynthesis, transport and catabolism
References
Gioffré et al., 2005: Gioffré A, Infante E, Aguilar D, Santangelo MP, Klepp L, Amadio A, Meikle V, Etchechoury I, Romano MI, Cataldi A, Hernández RP, Bigi F. Mutation in mce operons attenuates Mycobacterium tuberculosis virulence. Microbes and infection / Institut Pasteur. 2005; 7(3); 325-334. [PubMed: 15804490].