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copS

Victor ID 2638
Gene Name copS
Sequence Strain (Species/Organism) Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
NCBI Gene ID 1252613
NCBI Protein GI 16764453
Locus Tag STM1095
Protein Accession NP_460068.1
Other Database IDs UniProtKB-ID: Q8ZQ54_SALTY
UniRef100: UniRef100_B5BXZ4
UniRef90: UniRef90_B5FR23
UniRef50: UniRef50_P76339
UniParc: UPI00000CCFEB
EMBL: AE006468
EMBL-CDS: AAL20027.1
RefSeq_NT: NC_003197.1
GenomeReviews: AE006468_GR
KEGG: stm:STM1095
NMPDR: fig|99287.1.peg.1061
HOGENOM: HBG643531
OMA: ENTGAHI
ProtClustDB: CLSK880254
BioCyc: STYP99287:STM1095-MONOMER
Taxonomy ID 99287
Gene Starting Position 1182279
Gene Ending Position 1183643
Gene Strand (Orientation) -
Protein Name copper resistance protein
DNA Sequence 
>gi|16763390:1182279-1183643 Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 chromosome, complete genome
CTTAGCTATCACCACTATCAGGCAGACGAACCGAAAAGATATTATGTTCATCGGCATAGCGGTAAGATGC
CGAGCCACCGTGTAATAGAGCAATCGCGTTAACTAACGATAACCCCAGGCCGAAACCGGCAGTGTGGCGG
GCATTATCTCCTCGCCAAAAACGCCGGAAAAGCTTATCCGCATCGGCGGGGTGGCTGCCTGGATTAGCGA
CCCGAATTTCTGCAACGTTATCATCATAAGCGCTTTCAATACGTATCACGGCGTTTTCATCAGAATAACG
GATGGCATTCGTCAGCAGGTTTGAGAGCACTCTTTGTAATAATATTTCGTCAGCCCATACCGTTCCCTGA
CATTGATTTATAAAACAGATGCGCTTCTCCTCGGCAAGGGGGCTAAGATAATCCAGCATATTTTCGACCA
GCGCATTGAGCGAAACAGGCTGTTTTTTTACCGCTATATTCTGGTGCTCCGCGCGTGCCAGAAAGAGAAT
ATTTTCTGTCAGTCGCGACAGTCCCTCCAGCTCTTCAATATTATCGACAAGGGCTTGTTGATACTCTTCG
GCGCTGCGTTCCTGACTCAGCATCACCTGATTCTTCCCCAGTAAAATATTAACCGGCGTGCGCAGCTCAT
GCGCCAGATCGTCGGCAAATTGGTTCAGGCGTTCAAAATCGTCGGAAAGCTTCTGGCGCATGGTATTTAG
CGCTTGTCCAAGCGGCCTGAGCTCAACGGGTAACGCCTGTTCCGCCAACGGCTGGCGAAGTGTGCCGCTA
TCTGTCGCCGCGGTGAGTCGGCTGAGCGACGTAATGGCCCGCAGCCCGTTTCTGATGACTAATGGACTGA
GCGCCGAACAGACGAGGATCGCGATAAGGCTCATCAGCAAACTGTTGCGGCGATATTGCGCCAGCATTTG
CCGCCTTTCCGTCGCCAGCCTGGCAATAGTAAGGGTCAGCGGGTCATCGCCGCTTCTGGCGCTTACGCGT
ACCGCGGTCAGTTCCGTGCCTTGTACCGCCTGGCGAAATAAGGTTTCGCGGGTGATGTTTTTAGTCAGCG
GAATCTCGTTAAAGCGTTGGTCGGGGATGCCGCTATGATTAATCGCAACATTGTGGCCTGTTGCTGAATG
GATCAATAAGATGTCCTGCTTCGTATCCACCATCCGATTGAAATAGAGCGGCAGATTTTCCGGCCTGGCG
CCATCCAGTAACAGTTGCTGCATTTGCGCCGCCCGATTTATTAGCGTCATATCATCCCGATACGTTAATT
CTTTGCTCAGCGCGTTATAGAGCGTCCAGCTAATGCCGGTACAGGCGAGGATAAGGATGGCGATAAAAGA
AATTGTCAGGCGCAGCGTCATTGATAACTTAACCA
Protein Sequence 
>gi|576033374|ref|YP_009000616.1| copper resistance histidine kinase [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] MVKLSMTLRLTISFIAILILACTGISWTLYNALSKELTYRDDMTLINRAAQMQQLLLDGARPENLPLYFNRMVDTKQDILLIHSATGHNVAINHSGIPDQRFNEIPLTKNITRETLFRQAVQGTELTAVRVSARSGDDPLTLTIARLATERRQMLAQYRRNSLLMSLIAILVCSALSPLVIRNGLRAITSLSRLTAATDSGTLRQPLAEQALPVELRPLGQALNTMRQKLSDDFERLNQFADDLAHELRTPVNILLGKNQVMLSQERSAEEYQQALVDNIEELEGLSRLTENILFLARAEHQNIAVKKQPVSLNALVENMLDYLSPLAEEKRICFINQCQGTVWADEILLQRVLSNLLTNAIRYSDENAVIRIESAYDDNVAEIRVANPGSHPADADKLFRRFWRGDNARHTAGFGLGLSLVNAIALLHGGSASYRYADEHNIFSVRLPDSGDS
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: copS mutant is attenuated in mice (Lawley et al., 2006).
COG COG0642T, under T: Signal transduction mechanisms
References
Lawley et al., 2006: Lawley TD, Chan K, Thompson LJ, Kim CC, Govoni GR, Monack DM. Genome-wide screen for Salmonella genes required for long-term systemic infection of the mouse. PLoS pathogens. 2006; 2(2); e11. [PubMed: 16518469].