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pipA

Victor ID 2634
Gene Name pipA
Sequence Strain (Species/Organism) Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
NCBI Gene ID 1252605
NCBI Protein GI 16764445
Locus Tag STM1087
Protein Accession NP_460060.1
Other Database IDs UniProtKB-ID: Q8ZQ60_SALTY
UniRef100: UniRef100_D0ZTL2
UniRef90: UniRef90_B5FR16
UniRef50: UniRef50_B4T1J2
UniParc: UPI00000CCFE5
EMBL: AE006468
EMBL-CDS: AAL20019.1
RefSeq_NT: NC_003197.1
GenomeReviews: AE006468_GR
KEGG: stm:STM1087
NMPDR: fig|99287.1.peg.1053
HOGENOM: HBG671709
OMA: TYRLNTA
ProtClustDB: CLSK894064
BioCyc: STYP99287:STM1087-MONOMER
Taxonomy ID 99287
Gene Starting Position 1175547
Gene Ending Position 1176227
Gene Strand (Orientation) -
Protein Name pathogenicity island-encoded protein A
DNA Sequence 
>gi|16763390:1175547-1176227 Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 chromosome, complete genome
TCTATTTATTGAAGATGTAGACCATTCTGGGAGGTGAAGGATGCCCCATCTCTTTCAGAATAATGTTGGT
ATATTCGACAACAGGGCCTCTTGGATGATTTTCTTCTTTATCCTGAAGATGGGTCAGGGCATGTACAACT
TCATGAATAAATGAACGTTTTGTGTCAAAAAGTTGTCTTCCTTCGTTACTTTCATAATGTTCGGTATATG
AATCATCAGAATCGTCCAGATTGAGACAAATAACTTTCCTGCCTTCTGAAAGTTTGAAGTGTTCCTGAGC
CACGGTAGTTTCAAAGGCTTCGCCTGCCCCCAGTAGCCAGCGCTGCTCCACATCATGTAGTTCTTTTTCA
TATGCGTAATTCATCAGTCTGCGGAATGTTTCGCTTTGGGTATACGCATTTTGAAGTACGGAGGATAGTT
CATCGTAGCATTCGTCATAAGTGTCGTCATCAATTTCTGTATCAGGGTCTATTCCACCCGCGCCTGAGAT
AAGGTACTCCACCACACACTCTGGCTCCAGACGGAATTCACTGTTTATGGCAAGGCTGTCATGAGCAAGG
CGTAGCCGTGAGGGGTTTGGTGCATGTTCGGGAATATCGGGGAAAACAGGTGTATCTGCGGTATTTAATC
TATATGTGGATACTCCGCTTTGAGGTATTAATCTGTAGGTGACCGGAAGCA
Protein Sequence 
>gi|16764445|ref|NP_460060.1| pathogenicity island-encoded protein A [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] MLPVTYRLIPQSGVSTYRLNTADTPVFPDIPEHAPNPSRLRLAHDSLAINSEFRLEPECVVEYLISGAGGIDPDTEIDDDTYDECYDELSSVLQNAYTQSETFRRLMNYAYEKELHDVEQRWLLGAGEAFETTVAQEHFKLSEGRKVICLNLDDSDDSYTEHYESNEGRQLFDTKRSFIHEVVHALTHLQDKEENHPRGPVVEYTNIILKEMGHPSPPRMVYIFNK
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: pipA mutants have reduced epithelial cell invasion and reduced transepithelial migration of PMN compared to the wild type (Tenor et al., 2004).
References
Tenor et al., 2004: Tenor JL, McCormick BA, Ausubel FM, Aballay A. Caenorhabditis elegans-based screen identifies Salmonella virulence factors required for conserved host-pathogen interactions. Current biology : CB. 2004; 14(11); 1018-1024. [PubMed: 15182677].