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plsC

Victor ID 263
Gene Name plsC
Sequence Strain (Species/Organism) Mycobacterium tuberculosis H37Rv
NCBI Gene ID 887744
NCBI Protein GI 15609620
Locus Tag Rv2483c
Protein Accession NP_216999.1
Other Database IDs UniProtKB-ID: O53208_MYCTU
UniRef100: UniRef100_A5U5H9
UniRef90: UniRef90_A5U5H9
UniRef50: UniRef50_B2HNJ1
UniParc: UPI00000D5FDA
EMBL: AE000516
EMBL: BX842580
EMBL-CDS: AAK46860.1
EMBL-CDS: CAA16060.1
RefSeq_NT: NC_000962.2
RefSeq_NT: NC_002755.2
EnsemblGenome: EBMYCG00000000573.
EnsemblGenome_TRS: EBMYCT00000000573
EnsemblGenome_PRO: EBMYCP00000000573
EnsemblGenome: EBMYCG00000073067.
EnsemblGenome_TRS: EBMYCT00000073072
EnsemblGenome_PRO: EBMYCP00000071131
GenomeReviews: AE000516_GR
GenomeRev
Taxonomy ID 83332
Gene Starting Position 2789279
Gene Ending Position 2791021
Gene Strand (Orientation) -
Protein Name POSSIBLE TRANSMEMBRANE PHOSPHOLIPID BIOSYNTHESIS BIFUNCTIONNAL ENZYME PLSC: PUTATIVE L-3-PHOSPHOSERINE PHOSPHATASE (O-PHOSPHOSERINE PHOSPHOHYDROLASE) (PSP) (PSPASE) + 1-ACYL-SN-GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE (1-AGP ACYLTRANSFERASE) (1-AGPAT) (LYSOPH
DNA Sequence 
>gi|57116681:2789279-2791021 Mycobacterium tuberculosis H37Rv, complete genome
GTCACGACCGTCCTTTGGCGCTAGAGCTTGGCGATGCGGAGGCCTCACCATCCTTGCCAGCGATCTTAGA
TTCGCTGGGTTTGGCCTTCGGCGATGCCTTCTTTGTAGCCGCCTTCGTCGCGGCCGCGCCTTTATTGGCG
GCGCTTTTGGCGGGAGCCTTCTTAGCCGGCACCCTTTTCGCGGTGGCCTTGGCGACCTGAGCCCTGGCTT
TTCTGGCGGCCTTCTGCTCGGCGTACAGATCGACCGCGGGCAACCCATCGACCGGCCAGTCCGCCAGCGT
GTCCAGATACAGCTGGCGCACCTCGGCGATACGATCCGGCAGGGCGTCCAGGGTCCAGTCATCGACCGGA
ATCGGCGGAAACACCGCGACGTCGACCGTGCCCGGATTGATCGTGGTGGAGTTGCGCGAGGCGACGATCT
CCGCATTGCGGATCACGATCGGCACGATCGGGATCTTCGCGGCCATGGCGATACGGAAGGGCCCCTTCTT
GAATGACCCGACTTCGGTGGTATCCAACCGGGTACCTTCGGGAGCGATCACGATCGATAGTCCATTGCGG
GCGCGCTCCTCAACCGTGTGCAGTGTCTCCACCGCGGCGACCGGATCATCACGGTCGATGAACACACCGT
CCAGCAACTTCCCCAGCGTGCCCATGATCGGGTCGCTCGCCAGTTCCTTCTTGCCCACCCCAACCCAGTT
GTCGCGCACCAGCGCACCGGCAATGACCGGGTCAACCTGGTTGCGGTGGTTGAAGATAAAGACGGCGGGC
CGCTGGGCGGTCAGATTCTCTTTTCCGATCACATTCAGGTGCACGCCGCTGGTCGCCAGCAGCAGCTGAG
AGAAGGTGGAGGTAAAGAAATTCACGCCGCGGCGCCGGCTACCGGTCAGCACACCGATCCCTACCGCGCC
GGCCGCGACCGGGACGATGGTGCTCAGACCGGCAAGTGTCCGCAACTGCCGCCGGATGCCCACACCGCCG
CGACTGTTGAACTTCAAGATCGGCCAGCCCCGTCGCTTGGCGACCGCGGCCATCTTTCCTTCCGGATTGG
TCGGTCGCGGATTGCCCACCAGATACATCAGGGCGACGTCCTCGTCACCGTCGGCATAGAAGTAACTGTC
TTTGAGATCGATGTCGTGCTCGGCCGCAAAGCGTTGCACCGCAGTGGCTTTGCCCGGACACCACAAAATT
GGCTTCAGCACACCCCCGGTGAGTATCCCGTCCTCGTTGGTCTCGAACTTGTTGGTGAGCATGTTGTTGA
TCCCCAGAAAACGTGCGACTGGGCCAACTTGGATGGTCAGCGCCGACGAGCTGAGGACCACGGTGTGGCC
GCGGGCCACGTGAGCCCGGACCAGTTCCCGCATTTCCGGGTAGATCCGGGACTCGATCCGCTGGGCGAAT
AGCCGCTCGCCGATTTCTTCCAGGTCGGTCAAGAGCCGCCCGGCCAGCGCCGCGGCGGCCTTTCCGATAA
GGTCTTCGAACTCGATTCGCCCGAGCGTGTGATTCAGGCCGGCCTGAACCATACCGAGCAGCTCGCCCAC
GCCCATATCGCGGCGCCGCAGCCTCTCCTGGGTGAGGATGACGGCCGTGAAGCCGGCGACCAGCGTGCCG
TCCAGGTCGAAAAACGCACCGACCTTCGGGCCGGCAGGACTGGCCAGAATCTCGGCTACCGAACCGGGTA
GGCGCAAATCCGGCGCCGACTTCCGCGTCGCCCGCTCTTCCCCCTGCTCGTCAGCGGCGCTCA
Protein Sequence 
>gi|15609620|ref|NP_216999.1| bifunctional L-3-phosphoserine phosphatase/1-acyl-sn-glycerol-3-phosphate acyltransferase [Mycobacterium tuberculosis H37Rv] MSAADEQGEERATRKSAPDLRLPGSVAEILASPAGPKVGAFFDLDGTLVAGFTAVILTQERLRRRDMGVGELLGMVQAGLNHTLGRIEFEDLIGKAAAALAGRLLTDLEEIGERLFAQRIESRIYPEMRELVRAHVARGHTVVLSSSALTIQVGPVARFLGINNMLTNKFETNEDGILTGGVLKPILWCPGKATAVQRFAAEHDIDLKDSYFYADGDEDVALMYLVGNPRPTNPEGKMAAVAKRRGWPILKFNSRGGVGIRRQLRTLAGLSTIVPVAAGAVGIGVLTGSRRRGVNFFTSTFSQLLLATSGVHLNVIGKENLTAQRPAVFIFNHRNQVDPVIAGALVRDNWVGVGKKELASDPIMGTLGKLLDGVFIDRDDPVAAVETLHTVEERARNGLSIVIAPEGTRLDTTEVGSFKKGPFRIAMAAKIPIVPIVIRNAEIVASRNSTTINPGTVDVAVFPPIPVDDWTLDALPDRIAEVRQLYLDTLADWPVDGLPAVDLYAEQKAARKARAQVAKATAKRVPAKKAPAKSAANKGAAATKAATKKASPKAKPSESKIAGKDGEASASPSSSAKGRS
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: attenuated in mice (Sassetti and Rubin, 2003).
COG COG0560E, under E: Amino acid transport and metabolism
References
Sassetti and Rubin, 2003: Sassetti CM, Rubin EJ. Genetic requirements for mycobacterial survival during infection. Proceedings of the National Academy of Sciences of the United States of America. 2003; 100(22); 12989-12994. [PubMed: 14569030].