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pflA

Victor ID 2627
Gene Name pflA
Sequence Strain (Species/Organism) Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
NCBI Gene ID 1252488
NCBI Protein GI 161353606
Locus Tag STM0970
Protein Accession NP_459945.2
Taxonomy ID 99287
Gene Starting Position 1052687
Gene Ending Position 1053484
Gene Strand (Orientation) -
Protein Name pyruvate formate lyase-activating enzyme 1
DNA Sequence 
>gi|16763390:1052687-1053484 Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 chromosome, complete genome
ATTAATACATCACTTTATGACCATACTGCTCAAGAATACCCTTTACACGCTCCATGGTCTCTTTTTTAGG
CGGCTTCACGCCATCCAGTTTATATTCTTCGCCCATTGCCACCCATTTATGTTTGCCCAGCTCATGATAG
GGCAACAGTTCGATTTTTTCGACATTACCCATATCGCGGGTAAACTCGCCCAGGCGATGCGCGGAATCAT
CGTCGTCAGACCAGCCGGGAACGACAACGTAACGGATCCAGACCTTCACATTTTTCTTTGATAAATACTG
CGCGAATTCCAGCGTCCGGTGATTAGAGACACCGACCAGATTCTGGTGGATCTCATCATTCATCTGCTTG
AGATCGAGCATCACCAGATCGGTAACGTCCAACAGTTCATCAATCACCGGGTCATAACGGCGCACAAAGC
CGTTGGTGTCGAGACAGGTGTGGATACCTTCTTTTTTACAGGCGCGAAACCAGTCGCGTACAAATTCTGC
CTGCAAAATGGCCTCGCCGCCGGATGCCGTCACGCCGCCGCCAGAAGCATTCATAAAATGCCGATAGGTC
ACCACCTCTTTCATTAAGTCTTCAACGGTGATTTCTTTACCGCCATGCGTATCCCATGTGTCGCGGTTAT
GGCAATACAGGCAGCGCATCAGGCAGCCTTGAAAAAAGGTAATAAAGCGGATGCCTGGGCCATCAACGGT
GCCACAGGACTCAAAGGAGTGAATGCGACCAATAACCGGCTTTTTATCAGCAGTTACTGCAACACTTTCA
TTTGTAATACAATTGGTTAAGTTACTCA
Protein Sequence 
>gi|161353606|ref|NP_459945.2| pyruvate formate lyase-activating enzyme 1 [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] MSNLTNCITNESVAVTADKKPVIGRIHSFESCGTVDGPGIRFITFFQGCLMRCLYCHNRDTWDTHGGKEITVEDLMKEVVTYRHFMNASGGGVTASGGEAILQAEFVRDWFRACKKEGIHTCLDTNGFVRRYDPVIDELLDVTDLVMLDLKQMNDEIHQNLVGVSNHRTLEFAQYLSKKNVKVWIRYVVVPGWSDDDDSAHRLGEFTRDMGNVEKIELLPYHELGKHKWVAMGEEYKLDGVKPPKKETMERVKGILEQYGHKVMY
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: pflA mutant is attenuated in pigs (Carnell et al., 2007).
COG COG1180O, under O: Posttranslational modification, protein turnover, chaperones
References
Carnell et al., 2007: Carnell SC, Bowen A, Morgan E, Maskell DJ, Wallis TS, Stevens MP. Role in virulence and protective efficacy in pigs of Salmonella enterica serovar Typhimurium secreted components identified by signature-tagged mutagenesis. Microbiology (Reading, England). 2007; 153(Pt 6); 1940-1952. [PubMed: 17526851].