Search: for Help
About
Introduction
Statistics
Your PHIDIAS
Register or Login
Philert
Submission
Curated Data
Victors
BBP (Brucella)
Phinfo
Phinet
HazARD
Data Analysis
Phigen
Pacodom
BLAST
Help & Documents
Documents
FAQs
Links
Acknowledgements
Disclaimer
Contact Us
UMMS Logo

fimH

Victor ID 2611
Gene Name fimH
Sequence Strain (Species/Organism) Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
NCBI Gene ID 1252067
NCBI Protein GI 16763927
Locus Tag STM0547
Protein Accession NP_459542.1
Other Database IDs UniProtKB-ID: FIMH_SALTY
UniRef100: UniRef100_P37925
UniRef90: UniRef90_P37925
UniRef50: UniRef50_P37925
UniParc: UPI000012A7B6
EMBL: L19338
EMBL: AE006468
EMBL-CDS: AAA75420.1
EMBL-CDS: AAL19501.1
RefSeq_NT: NC_003197.1
GenomeReviews: AE006468_GR
KEGG: stm:STM0547
NMPDR: fig|99287.1.peg.532
HOGENOM: HBG416521
OMA: PPRNYIR
ProtClustDB: CLSK879696
BioCyc: STYP99287:STM0547-MONOMER
Taxonomy ID 99287
Gene Starting Position 608674
Gene Ending Position 609681
Gene Strand (Orientation) +
Protein Name minor fimbrial subunit
DNA Sequence 
>gi|16763390:608674-609681 Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 chromosome, complete genome
GATGAAAATATACTCAGCGCTATTGCTGGCGGGGACCGCGCTCTTTTTCACCCATCCCGCGCTGGCGACG
GTTTGCCGTAATTCAAACGGGACGGCGACCGATATCTTTTACGACCTGTCAGATGTTTTCACCAGCGGCA
ATAATCAGCCGGGACAGGTGGTGACGCTGCCGGAAAAATCAGGTTGGGTCGGCGTAAACGCGACGTGCCC
GGCGGGGACAACGGTGAATTATACCTACCGAAGCTATGTATCAGAATTACCGGTACAAAGTACCGAAGGA
AATTTTAAATACCTCAAGTTGAATGACTACCTTCTGGGCGCGATGAGCATCACCGATAGTGTCGCTGGCG
TATTTTATCCGCCCCGTAACTATATTCTCATGGGCGTCGACTATAACGTGTCGCAGCAAAAGCCGTTTGG
CGTGCAGGACTCAAAGCTGGTTTTTAAATTAAAAGTGATACGGCCTTTTATTAATATGGTGACGATCCCT
CGCCAGACAATGTTTACCGTCTATGTGACGACCTCTACCGGCGACGCGTTGAGCACGCCGGTATATACCA
TTAGCTACAGCGGCAAAGTGGAAGTGCCGCAAAACTGTGAAGTGAATGCCGGACAGGTCGTGGAGTTTGA
TTTCGGCGATATCGGCGCGTCGTTATTTAGTCAGGCGGGGGCGGGTAATCGTCCGCAAGGCGTCACGCCG
CAAACGAAAACCATTGCTATCAAATGTACCAACGTCGCGGCGCAGGCCTATTTATCGATGCGGCTTGAAG
CCGAAAAGGCCTCAGGGCAGGCGATGGTGTCCGATAATCCGGATTTAGGCTTTGTGGTTGCTAATAGCAA
CGGTACGCCGCTTACACCCAATAATTTGTCGAGTAAAATTCCGTTTCATCTTGATGATAACGCCGCCGCT
CGCGTAGGTATTCGCGCCTGGCCAATCAGCGTGACGGGGATTAAACCGGCGGAAGGGCCGTTTACTGCGC
GCGGCTATCTACGAGTCGATTATGATTA
Protein Sequence 
>gi|16763927|ref|NP_459542.1| fimbrial adhesin FimH [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] MKIYSALLLAGTALFFTHPALATVCRNSNGTATDIFYDLSDVFTSGNNQPGQVVTLPEKSGWVGVNATCPAGTTVNYTYRSYVSELPVQSTEGNFKYLKLNDYLLGAMSITDSVAGVFYPPRNYILMGVDYNVSQQKPFGVQDSKLVFKLKVIRPFINMVTIPRQTMFTVYVTTSTGDALSTPVYTISYSGKVEVPQNCEVNAGQVVEFDFGDIGASLFSQAGAGNRPQGVTPQTKTIAIKCTNVAAQAYLSMRLEAEKASGQAMVSDNPDLGFVVANSNGTPLTPNNLSSKIPFHLDDNAAARVGIRAWPISVTGIKPAEGPFTARGYLRVDYD
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: fimH mutants were impaired in binding and internalization of HeLa cells (Guo et al., 2007).
COG COG3539NU, under N: Cell motility; U: Intracellular trafficking, secretion, and vesicular transport
References
Guo et al., 2007: Guo A, Lasaro MA, Sirard JC, Kraehenbühl JP, Schifferli DM. Adhesin-dependent binding and uptake of Salmonella enterica serovar Typhimurium by dendritic cells. Microbiology (Reading, England). 2007; 153(Pt 4); 1059-1069. [PubMed: 17379714].