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spa47 from Shigella flexneri 5a

Victor ID 26
Gene Name spa47 from Shigella flexneri 5a
Sequence Strain (Species/Organism) Shigella flexneri 5a
NCBI Gene ID 876429
NCBI Protein GI 13449096
Locus Tag pWR501_p157
Protein Accession NP_085312.1
Other Database IDs UniProtKB-ID: SPAL_SHIFL
UniRef100: UniRef100_P0A1C1
UniRef90: UniRef90_P0A1C1
UniRef50: UniRef50_P0A1C0
UniParc: UPI0000135D9A
EMBL: M81458
EMBL: D13663
EMBL: AL391753
EMBL: AF348706
EMBL: AF386526
EMBL-CDS: AAA26541.1
EMBL-CDS: BAA02825.1
EMBL-CDS: CAC05824.1
EMBL-CDS: AAK18468.1
EMBL-CDS: AAL72302.1
RefSeq_NT: NC_002698.1
RefSeq_NT: NC_004851.1
EnsemblGenome: EBESCG00000093227
EnsemblGenome_TRS: EBESCT00000094183
EnsemblGenome_PRO: EBESCP00000090390
GenomeReviews: AF386526_GR
KEGG: sfl:CP0149
Taxonomy ID 623
Plasmid No pWR501
Gene Starting Position 122251
Gene Ending Position 123543
Gene Strand (Orientation) +
Protein Name ATP synthase SpaL
DNA Sequence 
>gi|13448939:122251-123543 Shigella flexneri 5a virulence plasmid pWR501, complete sequence
AATGAGCTATACAAAATTGCTCACTCAATTATCTTTTCCTAATAGAATCTCGGGGCCAATCTTGGAAACA
AGTCTTAGCGATGTTTCGATTGGTGAGATTTGTAACATTCAGGCTGGAATTGAAAGTAATGAAATTGTTG
CAAGAGCTCAGGTTGTAGGATTTCATGATGAAAAAACAATATTAAGCTTGATTGGAAATTCTCGTGGACT
TTCACGGCAAACATTGATTAAGCCCACTGCCCAGTTTCTTCATACGCAAGTCGGCCGTGGATTATTGGGA
GCAGTAGTCAATCCTTTAGGGGAGGTTACTGATAAGTTTGCTGTTACGGATAACAGTGAAATTCTTTATC
GACCTGTAGATAATGCTCCTCCGCTATATAGTGAAAGGGCTGCAATTGAGAAGCCTTTTTTAACAGGTAT
TAAGGTTATTGATTCTTTACTCACGTGTGGTGAAGGACAGCGAATGGGGATTTTTGCGTCAGCTGGTTGT
GGCAAAACTTTTCTCATGAATATGCTCATTGAACATAGTGGTGCTGATATATATGTTATTGGGTTAATTG
GTGAGCGAGGTCGAGAGGTTACTGAAACGGTTGATTATTTGAAAAACTCTGAGAAAAAAAGCAGGTGTGT
TTTAGTATATGCAACTTCGGATTACTCTTCGGTTGATCGTTGTAATGCTGCATATATAGCCACTGCTATA
GCCGAATTTTTTAGGACTGAAGGACATAAAGTAGCGCTTTTTATTGATTCATTAACAAGGTATGCCAGAG
CATTACGTGATGTGGCCTTAGCCGCTGGAGAATCACCTGCCAGAAGAGGCTATCCGGTTTCGGTTTTTGA
TAGCTTACCCAGACTTCTTGAAAGGCCAGGAAAGTTAAAGGCAGGTGGCTCTATTACTGCATTTTACACT
GTTCTTTTGGAGGATGATGATTTTGCTGATCCATTAGCTGAAGAGGTAAGATCCATTTTAGATGGACATA
TATATTTGAGCAGAAATCTAGCCCAAAAAGGACAATTTCCTGCAATTGATTCCTTAAAAAGTATAAGCAG
GGTATTTACACAGGTTGTTGATGAAAAACATCGTATTATGGCCGCTGCATTTCGGGAGCTACTTTCTGAA
ATAGAAGAGCTAAGGACAATTATTGACTTTGGTGAATACAAACCGGGGGAGAATGCCTCTCAGGATAAAA
TCTACAACAAAATATCTGTTGTTGAGAGTTTTCTGAAGCAAGATTATCGACTCGGTTTTACTTATGAGCA
GACAATGGAGCTTATTGGTGAAACAATTAGATA
Protein Sequence 
>gi|13449096|ref|NP_085312.1| invasion protein [Shigella flexneri 5a str. M90T] MSYTKLLTQLSFPNRISGPILETSLSDVSIGEICNIQAGIESNEIVARAQVVGFHDEKTILSLIGNSRGLSRQTLIKPTAQFLHTQVGRGLLGAVVNPLGEVTDKFAVTDNSEILYRPVDNAPPLYSERAAIEKPFLTGIKVIDSLLTCGEGQRMGIFASAGCGKTFLMNMLIEHSGADIYVIGLIGERGREVTETVDYLKNSEKKSRCVLVYATSDYSSVDRCNAAYIATAIAEFFRTEGHKVALFIDSLTRYARALRDVALAAGESPARRGYPVSVFDSLPRLLERPGKLKAGGSITAFYTVLLEDDDFADPLAEEVRSILDGHIYLSRNLAQKGQFPAIDSLKSISRVFTQVVDEKHRIMAAAFRELLSEIEELRTIIDFGEYKPGENASQDKIYNKISVVESFLKQDYRLGFTYEQTMELIGETIR
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: spa47 mutants form needle-less type III structure which is defective, and thus incapable of invasion of host cells (Tamano et al., 2000).
References
Tamano et al., 2000: Tamano K, Aizawa S, Katayama E, Nonaka T, Imajoh-Ohmi S, Kuwae A, Nagai S, Sasakawa C. Supramolecular structure of the Shigella type III secretion machinery: the needle part is changeable in length and essential for delivery of effectors. The EMBO journal. 2000; 19(15); 3876-3887. [PubMed: 10921870].