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leuO from Salmonella enterica subsp. enterica serovar Typhimurium str. LT2

Victor ID 2591
Gene Name leuO from Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
Sequence Strain (Species/Organism) Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
NCBI Gene ID 1251633
NCBI Protein GI 16763505
Locus Tag STM0115
Protein Accession NP_459120.1
Other Database IDs UniProtKB-ID: LEUO_SALTY
UniRef100: UniRef100_P46924
UniRef90: UniRef90_P46924
UniRef50: UniRef50_P46924
UniParc: UPI000012E5AD
EMBL: AE006468
EMBL: M12892
EMBL-CDS: AAL19079.1
EMBL-CDS: AAB02429.1
RefSeq_NT: NC_003197.1
GenomeReviews: AE006468_GR
KEGG: stm:STM0115
HOGENOM: HBG682110
OMA: APNIHLV
ProtClustDB: PRK09508
BioCyc: STYP99287:STM0115-MONOMER
Taxonomy ID 99287
Gene Starting Position 134568
Gene Ending Position 135512
Gene Strand (Orientation) +
Protein Name leucine transcriptional activator
DNA Sequence 
>gi|16763390:134568-135512 Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 chromosome, complete genome
TATGCCAGAGGTCAAAACCGAAAAGCCGCATCTTTTAGATATGGGCAAACCACAGCTTCGCATGGTTGAT
TTGAACCTATTGACCGTGTTCGATGCGGTAATGCAAGAGCAGAATATTACGCGCGCCGCCCACACGCTGG
GAATGTCGCAGCCTGCGGTCAGTAACGCCGTAGCGCGTCTGAAGGTTATGTTTAATGACGAACTTTTTGT
TCGATATGGACGAGGAATTCAGCCGACTGCCCGTGCATTTCAGTTATTTGGTTCAGTCCGTCAGGCGTTG
CAATTGGTGCAAAATGAATTGCCGGGATCGGGGTTTGAGCCGACCAGCAGCGAACGTGTATTCAATCTTT
GCGTGTGCAGTCCGCTGGATAATATCCTGACGTCACAGATTTATAATCGTGTAGAAAAAATTGCGCCAAA
TATTCATGTCGTTTTTAAAGCGTCGTTGAATCAGAATACTGAGCATCAGTTACGCTATCAGGAAACCGAG
TTCGTTATTAGTTATGAAGAATTCCGTCGTCCTGAGTTTACCAGCGTACCGCTATTTAAAGATGAAATGG
TTTTAGTCGCCAGCCGAAAACACCCGCGTATTAGCGGCCCGCTACTGGAAGGCGATGTTTATAATGAACA
ACATGCGGTTGTTTCCCTCGATCGTTATGCGTCATTTAGTCAGCCGTGGTATGACACGCCGGATAAACAG
TCGAGCGTGGCTTATCAGGGCATGGCGCTTATCAGCGTTCTGAACGTGGTTTCGCAGACGCATTTGGTCG
CTATTGCCCCGCGCTGGCTGGCGGAAGAGTTTGCGGAATCGCTGGATCTGCAAATATTGCCGTTGCCTTT
AAAACTGAATAGCCGGACATGCTACCTTTCCTGGCATGAAGCGGCTGGGCGTGATAAAGGGCATCAATGG
ATGGAAGATTTATTAGTCTCTGTTTGTAAGCGATA
Protein Sequence 
>gi|16763505|ref|NP_459120.1| HTH-type transcriptional regulator LeuO [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] MPEVKTEKPHLLDMGKPQLRMVDLNLLTVFDAVMQEQNITRAAHTLGMSQPAVSNAVARLKVMFNDELFVRYGRGIQPTARAFQLFGSVRQALQLVQNELPGSGFEPTSSERVFNLCVCSPLDNILTSQIYNRVEKIAPNIHVVFKASLNQNTEHQLRYQETEFVISYEEFRRPEFTSVPLFKDEMVLVASRKHPRISGPLLEGDVYNEQHAVVSLDRYASFSQPWYDTPDKQSSVAYQGMALISVLNVVSQTHLVAIAPRWLAEEFAESLDLQILPLPLKLNSRTCYLSWHEAAGRDKGHQWMEDLLVSVCKR
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: leuO mutant exhibited wild-type levels of epithelial invasion but highly reduced transepithelial migration of PMN (Tenor et al., 2004).
COG COG0583K, under K: Transcription
References
Tenor et al., 2004: Tenor JL, McCormick BA, Ausubel FM, Aballay A. Caenorhabditis elegans-based screen identifies Salmonella virulence factors required for conserved host-pathogen interactions. Current biology : CB. 2004; 14(11); 1018-1024. [PubMed: 15182677].